Enhancement of dissolution rate of aceclofenac by solid dispersion technique

International Journal of PharmTech Research

Volumn 1, Issue 4, 2009, Pages 1198-1204

  Patil, Sachin R ^a   Kumar, Ravi ^a   Patil, M B ^a   Paschapur, Mahesh S ^a   Rao, V S N Malleswara ^b  

^a Karnatak Lingayat Education Society   (India)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

Aceclofenac; Lactose; Mannitol; Solid dispersion; Urea

Indexed keywords

ACECLOFENAC; LACTOSE; MANNITOL; POLYMER; UREA;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG DETERMINATION; DRUG PURITY; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHILICITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; STRUCTURE ANALYSIS; WETTABILITY;

EID: 77953430441     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Chiou W L and Riegelman S. "Pharmaceutical applications of solid dispersion systems", J Pharm Sci., 1971; 60:1281-1302.
2. nd Edition, Vol.1, Marcel Dekker, New York. 2002, 641-647.
3. Leunner C and Dressman J. "Improving drug solubility for oral delivery using solid dispersions", Eur J Pharm Biopharm., 2000; 50:47-60. (Pubitemid 30326688)
4. Brahmankar BM and Jaiswal SB. Biopharmaceutics and Pharmacokinetics. Vallabh publications, New Delhi.171-172.
5. Lugar P, Daneck K, Engel W, Trummlitz G and Wagner K. "Structure and physiological properties of aceclofenac, a new NSAIDs", Eur J Pharm Sci., 1996;4:175-187. (Pubitemid 26174671)
6. Aceclofenac [Online][Cited 2007 Apr 23]; Available from URL: http://www.rxlist.com/cgi/generic/mobic cp.htm.
7. Aceclofenac B.P [Online][Cited 2007] Available from URL: http://www.technodrugs.com/aceclofenac.htm.
8. Aceclofenac [online] [Cited 2007 Apr 22]; Available from URL: http://www.medicinenet.com/aceclofenac/article.htm.
9. Hinz B, Auge D, Rau T, Rietbrock S, Brune K, Werner U. "Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography", Biomed Chromatogr., 2003;17:268-275 (Pubitemid 36818149)
10. Legrand E. "Aceclofenac in the management of inflammatory pain", Exp Opin Pharmacother., 2004;5:1347-1357
11. Babu P S, Ramu A, Sasidhar and Vidyadhara S. "Enhancement of dissolution rate of glimepride using newer carriers", Indian pharmacist., 2008; 69:65-68.
12. Dua K, Ramana M V, Sara U V S, Himaja M, Garg V and Agrawal A. "Dissolution enhancement of aceclofenac through solid dispersions", Indian pharmacist., 2006: 70-72.
13. Costa P and Lobo J M S. "Modelling and comparison of dissolution profiles", Eur J Pharm Sci., 2001; 13:123-133