Genetic and genomic insights into age at natural menopause

Genome Medicine

Volumn 1, Issue 8, 2009, Pages

  Moron, Francisco Jesus ^a   Ruiz, Agustin R ^a   Galan, Jose Jorge ^a  

^a Neocodex SL Avda ^*  (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; CYTOCHROME P450; CYTOCHROME P450 17A1; CYTOCHROME P450 1B1; ESTROGEN; GONADORELIN; HEXOKINASE; HEXOKINASE 3; UNCLASSIFIED DRUG;

AGE AT NATURAL MENOPAUSE; EARLY MENOPAUSE; FEMALE INFERTILITY; GENE CLUSTER; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MARKER; GENETIC RISK; GENETIC VARIABILITY; GENOMICS; HERITABILITY; HUMAN; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; PATHOGENESIS; PLESIOMORPHY; POSTMENOPAUSE; PRIORITY JOURNAL; SHORT SURVEY; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 77953401766     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/gm76     Document Type: Short Survey

References (13)

1. Kok HS, van Asselt KM, van der Schouw YT, Peeters PH, Wijmenga C: Genetic studies to identify genes underlying meno pausal age. Hum Reprod Update 2005, 11:483-493
2. de Bruin JP, Bovenhuis H, van Noord PA, Pearson PL, van Arendonk JA, te Velde ER, Kuurman WW, Dorland M: The role of genetic factors in age at natural menopause. Hum Reprod 2001, 16:2014-2018.
3. Hanna CW, Bretherick KL, Gair JL, Fluker MR, Stephenson MD, Robinson WP: Telomere length and reproductive aging. Hum Reprod 2009, 24:1206-1211.
4. Snieder H, MacGregor AJ, Spector TD: Genes control the cessation of a woman's reproductive life: a twin study of hysterectomy and age at menopause. J Clin Endocrinol Metab 1998, 83:1875-1880.
5. Weel AE, Uitterlinden AG, Westendorp IC, Burger H, Schuit SC, Hofman A, Helmerhorst TJ, van Leeuwen JP, Pols HA: Estrogen receptor polymorphism predicts the onset of natural and surgical menopause. J Clin Endocrinol Metab 1999, 84:3146-3150.
6. Hefler LA, Grimm C, Heinze G, Schneeberger C, Mueller MW, Muendlein A, Huber JC, Leodolter S, Tempfer CB: Estrogenmetabolizing gene polymorphisms and age at natural menopause in Caucasian women. Hum Reprod 2005, 20: 1422-1427.
7. Long JR, Shu XO, Cai Q, Wen W, Kataoka N, Gao YT, Zheng W: CYP19A1 genetic polymorphisms may be associated with obesity-related phenotypes in Chinese women. Int J Obes (Lond) 2007, 31:418-423.
8. van Disseldorp J, Broekmans FJ, Peeters PH, Fauser BC, van der Schouw YT: The association between vascular functionrelated genes and age at natural menopause. Menopause 2008, 15:511-516.
9. Tempfer CB, Riener EK, Keck C, Grimm C, Heinze G, Huber JC, Gitsch G, Hefler LA: Polymorphisms associated with thrombophilia and vascular homeostasis and the timing of menarche and menopause in 728 white women. Menopause 2005, 12:325-330.
10. van Asselt KM, Kok HS, Putter H, Wijmenga C, Peeters PH, van der Schouw YT, Grobbee DE, te Velde ER, Mosselman S, Pearson PL: Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age. Am J Hum Genet 2004, 74:444-453.
11. Murabito JM, Yang Q, Fox CS, Cupples LA: Genome-wide linkage analysis to age at natural menopause in a community-based sample: the Framingham Heart Study. Fertil Steril 2005, 84:1674-1679.
12. Stolk L, Zhai G, van Meurs JB, Verbiest MM, Visser JA, Estrada K, Rivadeneira F, Williams FM, Cherkas L, Deloukas P, Soranzo N, de Keyzer JJ, Pop VJ, Lips P, Lebrun CE, van der Schouw YT, Grobbee DE, Witteman J, Hofman A, Pols HA, Laven JS, Spector TD, Uitterlinden AG: Loci at chromosomes 13, 19 and 20 influence age at natural menopause. Nat Genet 2009, 41:645-647.
13. He C, Kraft P, Chen C, Buring JE, Paré G, Hankinson SE, Chanock SJ, Ridker PM, Hunter DJ, Chasman DI: Genomewide association studies identify loci associated with age at menarche and age at natural menopause. Nat Genet 2009, 41:724-728.