Dissolution profilling of nimesulide solid dispersions with polyethylene glycol, talc and their combinations as dispersion carriers

International Journal of PharmTech Research

Volumn 2, Issue 1, 2010, Pages 480-484

  Dhanaraju, M D ^a   Thirumurugan, G ^a  

^a GIET School of Pharmacy   (India)

Author keywords

Nimesulide; Polyethylene glycol 6000; Talc

Indexed keywords

MACROGOL 6000; NIMESULIDE; SOLVENT; TALC;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; MELTING POINT; SOLID;

EID: 77953395908     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Chiou WL, Riegelman S. 1971. Pharmaceutical applications of solid dispersion systems. J Pharm Sci; Sep; 60(9):1281-302.
2. Damian F, Blaton N, Naesens L 2000. Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14. Eur J Pharm Sci; 10:311Y322.
3. Ford JL. 1986. The current status of solid dispersions. Pharm Acta Helv; 61:69Y88.
4. Craig DQM. 2002. The mechanisms of drug release from solid dispersion in water-soluble polymers. Int J Pharm; 231:131Y144.
5. Abdul-Fattah AM, Bhargava HN. 2002. Preparation and in vitro evaluation of solid dispersions of halofantrine. Int J Pharm; 235:17Y33.
6. Sethia S, Squillante E. 2004. Solid dispersion of carbamazepine in PV K30 by conventional solvent evaporation and supercritical methods. Int J Pharm; 272:1Y10.
7. Pharmacopoeia of India 1996; Vol: 353.
8. Dhanaraju M.D, Enose A. 2001. Study of solid dispersion of Griseofulvin with Ployethylene glycol 6000: polysorbate 80 mixture. Indian Drugs; 38(12).