Anticonvulsant activity of Abutilon indicum leaf

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 2, Issue 1, 2010, Pages 66-70

  Golwala, Dharmesh K ^a   Patel, Laxman D ^b   Vaidya, Santosh K ^a   Bothara, Sunil B ^a   Mani, Munesh ^c   Patel, Piyush ^d  

^a C U SHAH UNIVERSITY   (India)

^b DHARMSINH DESAI UNIVERSITY   (India)

^c IFTM   (India)

^d Shri B M Shah College of Pharmacy Modasa   (India)

Author keywords

Abutilon indicum; Anticonvulsant; MES; PTZ

Indexed keywords

ABUTILON INDICUM EXTRACT; ALKALOID; AMINO ACID; CARBOHYDRATE; DIAZEPAM; FLAVONOID; GLYCOSIDE; PENTETRAZOLE; PHENOL DERIVATIVE; PHENYTOIN; PLANT EXTRACT; PROTEIN; SAPONIN; STEROID; TANNIN; TERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CONVULSION; ELECTRIC SHOCK; EXTRACTION; FEMALE; MALE; MEDICINAL PLANT; MORTALITY; MUCILAGE; NONHUMAN; RAT; REFERENCE VALUE; TIME OF DEATH; TONIC SEIZURE; WISTAR RAT;

EID: 77953389433     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants, Vol. II, New Delhi: Council of Science and Industrial Research; 1992.
2. Gaind KN, Chopra KS. Phytochemical investigation of Abutilon indicum. Planta Medica 1976;30: 174-185.
3. Baxi AJ, Parikh AR. Isolation of some non saponifiable principles from the leaves of Abutilon indicum (Linn.) Sweet. Ethnobotany Res 1980;1(4): 534-537.
4. Baxi AJ, Parikh AR. Free amino acids and sugar contents in the leaves of Abutilon indicum (Linn.) Sweet and Abutilon glaucum. J. Inst Chem 1981;53(3): 106-112.
5. Sharma PV, ZA Ahmed. Two sesquiterpene lactones from Abutilon indicum (Linn.) Sweet. Phytochemistry 1989;28(12): 35-25.
6. Sharma PV, Ahmed ZA, Sharma VV. Analgesic constituent of Abutilon indicum. Indian Drugs 1989;26(7): 333-337.
7. Matlawska I, Silkorska M. Flavonoid Compounds in the flowers of Abutilon indicum (Linn.) Sweet. Acta Pol Pharm 2002;59(3): 227-229.
8. Sammia Yasmin, Muhammad Akram Kashmiri, Iftikhar Ahmad, Ahmad Adnan, Mushtaq Ahmad. Biological Activity of Extracts in Relationship to Structure of Pure Isolates of Abutilon indicum. Pharmaceutical Biology 2008;46(10 & 11): 673-676.
9. rd ed. Vol. 1, Dehradun: International Book Publisher; 1983.
10. Yoganarasimhan SW. Medicinal Plants of India, Vol. II, Bangalore: Cyber Media; 2000.
11. Porchezhian E, Ansari SH. Effect of liquid extract from fresh Abutilon indicum leaves and Allium cepa bulbs on paracetamol and carbon tetrachloride induced hepatotoxicity. Pharmazie 2000;55: 702-705.
12. Porchezhian E, Ansari SH. Hepatoprotective activity of Abutilon indicum on Experimental liver damage in rats. Phytomedicine 2005;12:62-64
13. Kalyani GA. A preliminary pharmacological of Abutilon indicum analgesic activity. Fitoterapia 1985;56(3): 169-171.
14. Ahmed M, Amin S, Islam M, Takahashi M, Okuyama E. Analgesic principal from Abutilon indicum. Pharmazie 2000;55(4): 314-316.
15. Roshan S, Ali Sadath, Saleem MA, Patel MJ, Ali Asgar. Effect of Abutilon indicum on carbon tetrachloride induced hepatic damage in albino rats. J Pharma Res 2004;3(4): 61-62.
16. Seetharam G, Halageri, Setty SR, Bheemachar. Hypoglycemic activity of Abutilon indicum leaf extract in rats. Fitoterapia 2000:73(2): 156-159.
17. Roshan S, Sadath Ali, Abdullah Khan, Tazneem B, Purohit MG. Wound Healing activity of Abutilon indicum. Phcog Mag 2008; 4(15, Supp l): 85-88.
18. Adisakwattana S, Pudhom K, Yibchok-anun S. Influence of the methanolic extract from Abutilon indicum leaves in normal and streptozotocin-induced diabetic rats. African J of Biotechnology,: 2009;8(10): 2011-2015.
19. Chandrashekhar VM, Nagappa AN, Channesh TS, Habbu PV, Rao KP. Anti-diarrhoeal activity of Abutilon indicum Linn leaf extracts. J of Natural Remedies 2000;4: 12-16.
20. Rangari V. Pharmacognosy and Phytochemistry. Vol. I, Nashik: Career Publication; 2002.
21. Harbone JR. Phytochemical Methods: A guide to modern techniques of plant analysis. London: Chapman and Hall Ltd; 1984.
22. Khandelwal KR. Practical Pharmacognosy? Techniques and Experiments. Pune: Nirali Prakashan; 2002.
23. Turner RA: Anticonvulsants. In: Screening methods in Pharmacology. RA Turner Ed. Vol. I , New York and London: Academic Press, 1965. p. 64-65.
24. Khosla P, Pandhi P. Anticonvulsant effect of nimodipine alone and in combination with diazepam on PTZ induced convulsions. Ind J Pharmacol 2001;33: 208-211.
25. Swinyard EA. Electrically induced convulsions. In: Pupura DP, Penry JK, Tower D, Wodbury DM, Walter R. (Eds). Experimental Models of Epilepsy-A Manual for the Laboratory worker. New York: Raven Press; 1972. p. 433-58.
26. Loscher W, Schimidt D. Which animal model should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res 1988;2: 145-181.
27. Swinyard EA, Brown WC, Goodman LS. Comparitive assays of antiepileptic drugs in mice and rats. J Pharmacol Exp Thpr 1952;106: 319-330.
28. Yehuda S, Carrasso RL, Mostofsky DI. Essential fatty acid preparation (SR-3) raises threshhold in rats. Eur J of Pharmacol 1994;254: 193-198.
29. Voskuyl RA, Vreugndenhil M, Kang JX, Leaf A. Anticonvulsant effect of polyunsaturated fatty acids in rats, using cortical stimulation models. Eur J of Pharmacol 1998;341: 145-152.
30. Kavvadias D, Sand P, Youdim KA, Qaiser MZ, Rice-Evans C, Baur R et al. The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses blood brain barrier and exhibits anticonvulsive effect. Br J Pharmacol 2004;142: 811-820.
31. Du XM, Sun NY, Takizawa N, Guo YT, Shoyama Y. Sedative and anticonvulsant activity of goodyerin, a flavonol glycoside from Goodyera schlechtendaliana. Phytotheraputic Res 2002;16: 261-263.
32. Griebel G, Perrault G, Tan S, Shoemaker H, Sanger D. Pharmacological studies on synthetic flavonoids: comparision with diazepam. Neuropharmacology 1999;38: 965-977.