Simultaneous estimation of Rosuvastatin and Ezetimibe by ratio spectra derivative spectrophotometry method in their fixed dosage forms

International Journal of PharmTech Research

Volumn 2, Issue 1, 2010, Pages 404-410

  Gajjar, Anuradha K ^a   Shah, Vishal D ^a  

^a NIRMA UNIVERSITY   (India)

Author keywords

Ezetimibe; Ratio spectra derivative spectrophotometry; Rosuvastatin

Indexed keywords

EZETIMIBE; METHANOL; ROSUVASTATIN;

ABSORPTION SPECTROSCOPY; ACCURACY; ARTICLE; DRUG COMBINATION; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG STRUCTURE; RATIOSPECTRA DERIVATIVE SPECTROPHOTOMETRY; SPECTROPHOTOMETRY; TABLET FORMULATION; VALIDATION STUDY;

EID: 77953387720     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Lennernas H. and Fager G., Pharmacodynamic and pharmacokinetics of the HMG-Co-A reductase inhibitors, Clin. Pharmacokinet., 1997, 32, 403-425. 2. Leitersdorf E., Selective cholesterol absorption inhibition: a novel strategy in lipid-lowering management, Int. J. Clin. Pract., 2002, 56, 116-119.
2. Heek M.V., Farley C., Compton D., Hoos L. and Davis H.R., Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function, Br. J. Phamacol., 2001, 134(2), 409-417.
3. Kumar T.R., Shitut N.R., Kumar P.K., Vinu M.C., Kumar V.V. and Mullangi R., Determination of Rosuvastatin in rat plasma by HPLC: Validation and its application to pharmacokinetic studies, Biomed. Chromatogr., 2006, 20, 881-887.
4. Vittal S., Kumar T.R., Shitut N.R., Vinu M.C., Kumar V.V. and Mullangi R., Simultaneous quantitation of Rosuvastatin and Gemfibrozil in human plasma by high-performance liquid chromatography and its application to a pharmacokinetic study, Biomed. Chromatogr., 2006, 20, 1252-1259.
5. Mehta T.N., Patel A.K., Kulkarni G.M. and Suubbaiah G., Determination of Rosuvastatin in the presence of its degradation products by a stability-indicating LC method, J. AOAC Int., 2005, 88(4), 1142-1147.
6. Suslu I., Celebier M. and Altinoz S., Determination of Rosuvastatin in Pharmaceutical Formulations by Capillary Zone Electrophoresis, Chromatographia, 2007, 66, 65-72.
7. Uyar B., Celebier M. and Altinoz S., Spectrophotometric determination of Rosuvastatin calcium in tablets, Pharmazie, 2007, 62, 411-413.
8. Sane R.T., Kamat S.S., Menon S.N., Inamdar S.R. and Mote M.R., Determination of Rosuvastatin calcium in its bulk drug and pharmaceutical preparations by high-performance thin-layer chromatography, J. Planar Chromatogr., 2007, 18, 194-198.
9. Sistla R., Tata V.S., Kashyap Y.V., Chandrasekar D. and Diwan P.V., Development and validation of a reversed-phase HPLC method for the determination of Ezetimibe in pharmaceutical dosage forms, J. Pharm. Biomed. Anal., 2005, 39, 517-522.
10. Akmar S.K., Kothapalli L., Thomas A., Jangam S. and Deshpande A.D., Reverse Phase HPLC method for the estimation of Ezetimibe in bulk and pharmaceutical formulations, Indian J. Pharm. Sci., 2007, 69(5), 695-697.
11. Singh S., Singh B., Bahuguna R., Wadhwa L. and Saxena R., Stress degradation studies on Ezetimibe and development of a validated stability-indicating HPLC assay, J. Pharm. Biomed. Anal., 2006, 41, 1037-1040.
12. Doshi A.S., Kachhadia P.K. and Joshi H., Validation of a stability-indicating LC method for assay of Ezetimibe in tablets and for determination of content uniformity, Chromatographia 2008, 67, 137-142.
13. Oswald S., Scheuch E., Cascorbi I. and Siegmund W., A LC-MS/MS method to quantify the novel cholesterol lowering drug Ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2006, 830, 143-150.
14. Li S., Liu G., Jia J., Li X. and Yu C.J., Liquid chromatography-negative ion electrospray tandem mass spectrometry method for the quantification of Ezetimibe in human plasma, J. Pharm. Biomed. Anal., 2006, 40(4), 987-992.
15. Jain N., Jain R., Swami H., Pandey S. and Jain D.K., Spectrophotometric method for simultaneous estimation of Simvastatin and Ezetimibe in bulk drug and its combined dosage form, Int. J. Pharm. Pharm. Sci., 2009, 1(1), 170-175.
16. Chaudhari B.G., Patel M.N., Shah P.B., Patel L.J. and Patel V.P., Stability-indicating reversed-phase liquid chromatography method for simultaneous determination of Atrovastatin and Ezetimibe from their combination drug products, J. AOAC Int., 2007, 90(6), 1539-1546.
17. Chaudhari B.G., Patel N.M. and Shah P.B., Stability-indicating reversed-phase liquid chromatographic method for simultaneous determination of Simvastatin and Ezetimibe from their combination drug products, J. AOAC Int., 2007, 90(5), 1242-49.
18. Salinas F., Nevado J.J. and Espinosa M.A., A new spectrophotometric method for quantitative multicomponent analysis resolution of mixtures of Salicylic and Salicyluric acids, Talanta, 1990, 37(3), 347-351.
19. Nevado J.J., Guiberteau C.C. and Salinas F., Spectrophotometric resolution of ternary mixtures of salicylaldehyde, 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde by the derivative ratio spectrum-zero crossing method, Talanta, 1992, 39(5), 547-553.
20. El-Gindy A., Ahmed A., Laila A.F. and Shabana M.M., Spectrophotometric determination of benazepril hydrochloride and hydrochlorothiazide in binary mixture using second derivative, second derivative of the ratio spectra and chemometric methods, J. Pharm. Biomed. Anal., 2001, 25(2), 299-307.
21. 2B, Geneva, Switzerland, 1996.