Stress degradation studies on ezetimibe and development of a validated stability-indicating HPLC assay

Journal of Pharmaceutical and Biomedical Analysis

Volumn 41, Issue 3, 2006, Pages 1037-1040

  Singh, Saranjit ^a   Singh, Baljinder ^a   Bahuguna, Rakesh ^b   Wadhwa, Lalit ^b   Saxena, Rahul ^b  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b Ind Swift Laboratories Limited   (India)

Author keywords

Assay; Degradation; Ezetimibe; Stability indicating; Stress testing; Validation

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; AMMONIUM HYDROXIDE; BUFFER; EZETIMIBE;

ACCURACY; ALKALINITY; ARTICLE; DRUG DEGRADATION; DRUG DETERMINATION; DRUG HYDROLYSIS; DRUG STABILITY; HEAT STRESS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; OXIDATIVE STRESS; PH; PHOTODEGRADATION; PHOTOLYSIS; PHYSICAL STRESS; PRIORITY JOURNAL; STRESS; THERMOSTABILITY; VALIDATION STUDY; VALIDITY;

AZETIDINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; OXIDATIVE STRESS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 33646395668     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.01.030     Document Type: Article

References (7)

1. ICH, Stability Testing of New Drug Substances and Products Q1A (R2), International Conference on Harmonization, IFPMA, Geneva, 2003.
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3. Bakshi M., and Singh S. J. Pharm. Biomed. Anal. 28 (2002) 1011-1040
4. http://www.rxlist.com/cgi/generic/ezetimibe.htm, 2005 (accessed on 15.12.2005).
5. Ezzet F., Krishna G., Wexler D.B., Statkevich P., Kosoglou T., and Batra V.K. Clin. Ther. 23 (2001) 871-885
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7. G.Y.S.K. Swamy, K. Ravikumar, L. K. Wadhwa, R. Saxena, S. Singh, Acta Cryst. Section E, 61 (2005) o3608-o3610.