Possible molecular basis of cardioprotective effects of green tea

Mediterranean Journal of Nutrition and Metabolism

Volumn 2, Issue 1, 2009, Pages 15-19

  Pasini, E ^a   Stephanou, A ^b   Scarabelli, C C ^c   Corsetti, G ^d   Aquilani, R ^a   Scarabelli, T M ^e  

^a IRCCS   (Italy)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF BRESCIA   (Italy)

^e WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Green tea; Heart; Ischaemia; Reperfusion

Indexed keywords

EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; OXYGEN RADICAL; STAT1 PROTEIN; STAT3 PROTEIN;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DRUG MECHANISM; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; RISK REDUCTION; SPRAGUE DAWLEY RAT; TEA; TREATMENT DURATION;

RATTUS;

EID: 77953384525     PISSN: 1973798X     EISSN: 19737998     Source Type: Journal    
DOI: 10.1007/s12349-009-0036-8     Document Type: Article

References (13)

1. J.V. Higton B. Frei 2003 Tea catechins and polyphenols: health effects, metabolism, and antioxidant function Crit Rev Food Sci Nutr 43 89 143 10.1080/10408690390826464 (Pubitemid 38552312)
2. M. Menegazzi E. Tedeschi D. Dussin, et al. 2001 Anti-interferon gamma action of epigallocatechin-3-gallate mediated by specific inhibition of STAT1 activation FASEB J 15 1309 1311 1:CAS:528:DC%2BD3MXlvVOrt74%3D
3. T.M. Scarabelli A. Stephanou E. Pasini, et al. 2002 Different signalling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischaemia/reperfusion injury Circ Res 90 745 748 10.1161/01.RES.0000015224. 07870.9A 1:CAS:528:DC%2BD38XjtF2gu78%3D (Pubitemid 34640895)
4. R. Ferrari A. Cargnoni P. Bernocchi, et al. 1996 Metabolic adaptation during a sequence of no-flow and low-flow ischemia: a possible trigger for hibernation Circulation 94 2587 2596 1:STN:280:DyaK2s%2FotVClsg%3D%3D
5. A. Stephanou B.K. Brar T. Scarabelli, et al. 2000 Ischaemia-induced STAT-1 expression and activation plays a critical role in cardiac myocyte apoptosis J Biol Chem 275 10002 10008 10.1074/jbc.275.14.10002 1:CAS:528:DC%2BD3cXisFWjsr4%3D (Pubitemid 30202047)
6. A. Stephanou D.S. Latchman 2005 Opposing actions of STAT-1 and STAT-3 Growth Factor 23 177 182 10.1080/08977190500178745 1:CAS:528:DC%2BD2MXhtFCjtrnO (Pubitemid 43203048)
7. A. Stephanou B.K. Brar R.A. Knight D.S. Latchman 2000 Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters Cell Death Differentiation 7 329 330 10.1038/sj.cdd.4400656 1:CAS:528:DC%2BD3cXis1Clsro%3D
8. A. Stephanou T. Scarabelli P.A. Townsend, et al. 2002 The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischaemia/reperfusion-induced apoptosis in cardiac myocytes FASEB J 16 1841 1843 1:CAS:528:DC%2BD38XoslOgt7Y%3D
9. A. Stephanou 2002 Activated STAT-1 pathway in the myocardium as a novel therapeutic target in ischaemia/reperfusion injury European Cytokine Network 13 387 390
10. A. Stephanou T. Scarabelli B.K. Brar, et al. 2001 Induction of apoptosis and Fas/FasL expression by ischaemia/reperfusion in cardiac myocytes requires serine 727 of the STAT1 but not tyrosine 701 J Biol Chem 276 28340 28347 10.1074/jbc.M101177200 1:CAS:528:DC%2BD3MXls1Srtrc%3D
11. M. Menegazzi E. Tedeschi D. Dussin, et al. 2001 Anti-interferon gamma action of epigallocatechin-3-gallate mediated by specific inhibition of STAT1 activation FASEB J 15 1309 1311 1:CAS:528:DC%2BD3MXlvVOrt74%3D
12. P.A. Townsend T.M. Scarabelli E. Pasini, et al. 2004 Epigallocatechin-3- gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis FASEB J 18 1621 1623 1:CAS:528: DC%2BD2cXotFGhsr0%3D
13. E. Roth 1998 The impact of L-arginine-nitric oxide metabolism on ischaemia/reperfusion injury Curr Opin Clin Nutr Metab Care 1 97 99 10.1097/00075197-199801000-00016 1:CAS:528:DyaK1MXht1WqtLs%3D