Metabolic adaptation during a sequence of no-flow and low-flow ischemia: A possible trigger for hibernation

Circulation

Volumn 94, Issue 10, 1996, Pages 2587-2596

  Ferrari, R ^a,e   Cargnoni, A ^b   Bernocchi, P ^b   Pasini, E ^b   Curello, S ^a   Ceconi, C ^a   Ruigrok, T J C ^c,d  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Ctr of Cardiovasc Pathophysiology   (Italy)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^e SPEDALI CIVILI   (Italy)

Author keywords

ischemia; metabolism; myocardial hibernation; preconditioning

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE KINASE; CREATINE PHOSPHATE; GLUTATHIONE; GLUTATHIONE DISULFIDE; LACTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ADAPTATION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DIASTOLIC BLOOD PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE METABOLISM; HEART MUSCLE PERFUSION; HEART MUSCLE REPERFUSION; HEART PERFORMANCE; ISOLATED HEART; MALE; NONHUMAN; OXIDATIVE STRESS; PH; PRIORITY JOURNAL; RABBIT;

EID: 0029828495     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.10.2587     Document Type: Article

References (41)

1. Rahimtoola SH. A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina. Circulation. 1985;72(suppl V):V-123-V-135.
2. Rahimtoola SH. The hibernating myocardium. Am Heart J. 1989; 117:211-221.
3. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124-1136.
4. Braunwald E, Rutherford JD. Reversible ischemic left ventricular dysfunction: evidence for the 'hibernating myocardium.' J Am Coll Cardiol. 1986;8:1467-1470.
5. La Canna G, Alfieri O, Giubbini R, Gargano M, Ferrari R, Visioli O. Echocardiography during infusion of dobutamine for identification of reversible dysfunction in patients with chronic coronary artery disease. J Am Coll Cardiol. 1994;23:617-626.
6. Ferrari R, La Canna G, Giubbini R, Ceconi C, Pardini A, Coletti G, Berra P, Alfieri O. Hibernating myocardium. In: Yacoub M, Pepper J, eds. Annual of Cardiac Surgery. London, UK: Current Science Ltd; 1994:28-32.
7. Ferrari R, Curello S, Ceconi C, Cargnoni A, Pasini E, Visioli O, Cardioprotection by nisoldipine: role of timing of administration. Eur Heart J. 1993;14:1258-1272.
8. Cobbe SM, Poole-Wilson PA. Catheter tip pH electrode for use in man. J Physiol. 1979;289:3P-4P.
9. Oliver TA. A spectrophotometric method for the determination of creatine phosphokinase and myokinase. Biochem J. 1955;61: 116-122.
10. Hohrost HJ, Krentz FH, Bucher T. Metabolitgehalte und Metabolitkonzentration in der Labor der Ratte. Biochem Zeitschr. 1959; 932:18-22.
11. Ferrari R, Pedersini P, Bongrazio M, Gaia G, Bernocchi P, Di Lisa F, Visioli O. Mitochondrial energy production and cation control in myocardial ischemia and reperfusion. Basic Res Cardiol. 1993;88: 495-512.
12. Sordhal LA, McCollum WB, Wodd WG, Schwartz A. Mitochondria and sarcoplasmic reticulum function in cardiac hypertrophy and failure. Am J Physiol. 1973;244:497-502.
13. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle for protein binding. Anal Biochem. 1978;72:248-254.
14. Bernocchi P, Ceconi C, Cargnoni A, Pedersini P, Curello S, Ferrari R. Extraction and assay of creatine phosphate, purine and pyridine in cardiac tissue by reversed-phase high-performance liquid chromatography. Anal Biochem. 1994;222:374-379.
15. Curello S, Ceconi C, Cargnoni A, Cornacchiari A, Ferrari R, Albertini A. Improved procedure for determining glutathione in plasma as an index of myocardial oxidative stress. Clin Chem. 1987;33: 1448-1449.
16. Ferrari R, Alfieri O, Curello S, Ceconi C, Cargnoni A, Marzollo P, Pardini A, Caradonna E, Visioli O. Occurrence of oxidative stress during reperfusion of the human heart. Circulation. 1990; 81:201-211.
17. Sedlack J, Lindsay RH. Estimation of total, protein-bound, and non-protein sulphydryl groups in tissue with Ellman's reagent. Anal Biochem. 1968;25:192-205.
18. Bolukoglu H, Liedtke AJ, Nellis SH, Eggleston AM, Subramanian R, Renstrom B. An animal model of chronic coronary stenosis resulting in hibernating myocardium. Am J Physiol. 1992;263: H20-H29.
19. Bristow JD, Arai AE, Anselone CG, Pantely GA. Response to myocardial ischemia as a regulated process. Circulation. 1991; 84:2580-2587.
20. Ross J. Myocardial perfusion-contraction matching: implications for coronary heart disease and hibernation. Circulation. 1991;83: 1076-1083.
21. Nayler WG, Ferrari R, Poole-Wilson PA, Yepez CE. A protective effect of a mild acidosis on hypoxic heart muscle. J Mol Cell Cardiol. 1979;11:1053-1071.
22. Ito BR. Gradual onset of myocardial ischemia results in reduced myocardial infarction: association with reduced contractile function and metabolic downregulation. Circulation. 1995;91:2058-2070.
23. Schulz R, Post H, Sakka S, Wallbridge DR, Heusch G. Intraischemic preconditioning: increased tolerance to sustained low-flow ischemia by a brief episode of no-flow ischemia without intermittent reperfusion. Circ Res. 1995;76:942-950.
24. 31P NMR study in rat hearts. J Mol Cell Cardiol. In press.
25. Cohen MV, Liu GS, Downey JM. Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits. Circulation. 1991;84:341-349.
26. Yellon DM, Alkhulaifi M, Browne EE, Pugsley WB. Ischemic preconditioning limits infarct size in the rat heart. Cardiovasc Res. 1992;26;983-987.
27. Yellon DM, Pasini E, Cargnoni A, Marber M, Latchman DS, Ferrari R. The protective role of heat stress in the ischaemic and reperfused rabbit myocardium. J Mol Cell Cardiol. 1992;24:895-907.
28. Kloner RA, Shook T, Przyklenk K, Davis VG, Junio L, Matthews RV, Burstein S, Gibson CM, Poole WK, Cannon CP, McCabe CH, Braunwald E. Previous angina alters in-hospital outcome in TIMI 4: a clinical correlate to preconditioning. Circulation. 1995;91:37-47.
29. Koning MMG, Simonis LAJ, deZeeuw S, Nieukoop S, Post S, Verdouw PD. Ischaemic preconditioning by partial occlusion without intermittent reperfusion. Cardiovase Res. 1994;28:1146-1151.
30. Ovize M, Przyklenk K, Kloner RA. Partial coronary stenosis is sufficient and complete reperfusion is mandatory for preconditioning in the canine heart. Circ-Res. 1992;71:1165-1173.
31. Walsh RS, Borges M, Thornton JD, Cohen MV, Downey JM. Hypoxia preconditions rabbit myocardium by an adenosine receptor-mediated mechanism. Can J Cardiol. In press.
32. 1 adenosine receptors in rabbit heart. Circulation. 1991;84:350-356.
33. Schulz R, Rose J, Heusch G. Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine. Am J Physiol. 1994;267:H1341-H1352.
34. Baxter GF, Yellon DM. Ischaemic preconditioning of myocardium: a new paradigm for clinical cardioprotection? Br J Clin Pharmacol. 1994;38:381-387.
35. Reimer KA, Vander Heide RS, Murry CE, Jennings RB. Role of altered energy metabolism in ischemic preconditioning. In: Przyklenk K, Kloner RA, Yellon DM, eds. Ischemic Preconditioning: The Concept of Endogenous Cardioprotection. Boston, Mass: Kluwer Academic Publishers; 1994:75-103.
36. Marber MS, Latchman DS, Walker JM, Yellon DM. Cardiac stress protein elevation 24 hours following brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation. 1993;88:1264-1272.
37. Schulz R, Guth BD, Pieper K, Martin C, Heusch G, Recruitment of an inotropic reserve in moderately ischemic myocardium at the expense of metabolic recovery: a model of short-term hibernation. Circ Res. 1992;70:1282-1295.
38. Fedele FA, Gewirtz H, Capone RJ, Sharaf B, Most AS. Metabolic response to prolonged reduction of myocardial blood flow distal to a severe coronary artery stenosis. Circulation. 1988;78:729-735.
39. Matsuzaki M, Gallagher KP, Kemper WS, White F, Ross J Jr. Sustained regional dysfunction produced by prolonged stenosis: gradual recovery after reperfusion. Circulation. 1983;68:170-182.
40. Heyndrickx GR, Wijns W, Vogelaers D, Degrieck Y, Bol A, Vandeplassche G, Melin JA. Recovery of regional contractile function and oxidative metabolism in stunned myocardium induced by 1-hour circumflex coronary artery stenosis in chronically instrumented dogs. Circ Res. 1993;72:901-913.
41. Cobbe SM, Poole-Wilson PA. The time course and severity of acidosis in myocardial ischaemia. J Mol Cell Cardiol. 1980;12:754-760.