Role of leukotriene B4 in 5-lipoxygenase metabolite-and allergy-induced itch-associated responses in mice

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 6, 2010, Pages 1050-1053

  Tsuji, Fumio ^a,b   Aono, Hiroyuki ^a   Tsuboi, Takashi ^a   Murakami, Tadahiro ^a   Enomoto, Hiroshi ^a   Mizutani, Keiko ^a   Inagaki, Naoki ^b,c  

^a SANTEN PHARMACEUTICAL CO LTD   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Hydrolase; Leukotriene a4; Leukotriene B4; Passive cutaneous anaphylaxis; SA6541; Scratching behavior

Indexed keywords

4 DIMETHYLAMINOBENZYL N (3 MERCAPTO 2 METHYLPROPIONYL)CYSTEINE; 5 HYDROPEROXY 6,8,11,14 ICOSATETRAENOIC ACID; HYDROLASE INHIBITOR; KETOTIFEN FUMARATE; LEUKOTRIENE B4; SA 6541; UNCLASSIFIED DRUG; ARACHIDONIC ACID; EPOXIDE HYDROLASE; HISTAMINE H1 RECEPTOR ANTAGONIST; KETOTIFEN; LEUKOTRIENE A4 HYDROLASE; LIPOXYGENASE; PROTEINASE INHIBITOR;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG SPECIFICITY; DRUG TARGETING; MALE; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRURITUS; SCRATCHING; SKIN ALLERGY; ANIMAL; ANIMAL BEHAVIOR; CAPILLARY PERMEABILITY; DRUG ANTAGONISM; DRUG EFFECT; HYPERSENSITIVITY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PHYSIOLOGY; SKIN;

ANIMALS; ARACHIDONIC ACID; BEHAVIOR, ANIMAL; CAPILLARY PERMEABILITY; EPOXIDE HYDROLASES; HISTAMINE H1 ANTAGONISTS; HYPERSENSITIVITY; KETOTIFEN; LEUKOTRIENE B4; LIPOXYGENASE; MALE; MICE; MICE, INBRED ICR; PASSIVE CUTANEOUS ANAPHYLAXIS; PROTEASE INHIBITORS; PRURITUS; SKIN;

EID: 77953377219     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.1050     Document Type: Article

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