Effects of SA6541, a leukotriene A4 hydrolase inhibitor, and indomethacin on carrageenan-induced murine dermatitis

European Journal of Pharmacology

Volumn 346, Issue 1, 1998, Pages 81-85

  Tsuji, Fumio ^a   Miyake, Yurika ^a   Enomoto, Hiroshi ^a   Horiuchi, Masato ^a   Mita, Shiro ^a  

^a SANTEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Dermatitis; Indomethacin; Leukotriene A4 hydrolase inhibitor; Leukotriene B4; SA65411

Indexed keywords

(4 DIMETHYLAMINOBENZYL) N (3 MERCAPTO 2 METHYLPROPIONYL)CYSTEINE; CARRAGEENAN; HYDROLASE INHIBITOR; INDOMETACIN; LEUKOTRIENE A4; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; ARTICLE; DERMATITIS; EDEMA; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANILINE COMPOUNDS; ANIMALS; CARRAGEENAN; CYSTEINE; DERMATITIS, CONTACT; EDEMA; ENZYME INHIBITORS; EPOXIDE HYDROLASES; INDOMETHACIN; LEUKOTRIENE B4; MALE; MICE; MICE, INBRED ICR;

EID: 0032478676     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00127-7     Document Type: Article

References (22)

1. Aked D.M., Foster S.J. The contribution of eicosanoids to the acute inflammatory reaction induced by arachidonic acid in rabbit skin. Br. J. Pharmacol. 92:1987;545-552.
2. Chen X.S., Sheller J.R., Johnson E.N., Funk C.D. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature. 372:1994;179-182.
3. Dozen M., Yamaki K., Oh-ishi S. Captopril uncovers kinin-dependent release of arachidonic acid metabolites in carrageenin-induced rat pleurisy. Jpn. J. Pharmacol. 51:1989;101-105.
4. 4: A potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature. 286:1980;264-265.
5. 4 receptor antagonist, SC-41930. Inflammation. 14:1990;727-739.
6. 4 receptor antagonist, SC-53228. Inflammation. 19:1995;333-346.
7. 4 stimulates polymorphonuclear leukocyte adhesion to cultured vascular endothelial cells. J. Clin. Invest. 74:1984;1552-1555.
8. Lewis R.A., Austen K.F., Soberman R.J. Leukotrienes and other products of the 5-lipoxygenase pathway: Biochemistry and relations to pathobiology in human diseases. New Engl. J. Med. 323:1990;645-655.
9. 4 in the human lung. Recruitment of neutrophils into alveolar spaces without a change in protein permeability. J. Clin. Invest. 84:1989;1609-1619.
10. 4) in the rabbit. Am. J. Pathol. 115:1984;233-244.
11. 4 receptor. J. Lipid Mediators Cell Signal. 10:1994;213-228.
12. 4 antagonists in the mouse ear edema and rat neutropenia models. Inflamm. Res. 44:1995;S141-S142.
13. 2. J. Invest. Dermatol. 88:1987;120-123.
14. 4 towards rabbit neutrophils. J. Immunol. 128:1982;811-816.
15. 4 during experimental inflammation. Biochem. Pharmacol. 32:1983;1353-1354.
16. 4) in human skin. J. Invest. Dermatol. 80:1983;115-119.
17. 4 in murine dermatitis models. Biochem. Pharmacol. 55:1998;297-304.
18. Utsunomiya I., Nagai S., Oh-ishi S. Sequential appearance of IL-1 and IL-6 activities in rat carrageenin-induced pleurisy. J. Immunol. 147:1991;1803-1809.
19. Utsunomiya I., Nagai S., Oh-ishi S. Differential effects of indomethacin and dexamethasone on cytokine production in carrageenin-induced rat pleurisy. Eur. J. Pharmacol. 252:1994;213-218.
20. Utsunomiya I., Ito M., Watanabe K., Tsurufuji S., Matsushima K., Oh-ishi S. Infiltration of neutrophils by intrapleural injection of tumour necrosis factor, interleukin-1, and interleukin-8 in rats, and its modification by actinomycin D. Br. J. Pharmacol. 117:1996;611-614.
21. Wedmore C.V., Williams T.J. Control of vascular permeability by polymorphonuclear leukocytes in inflammation. Nature. 289:1981;646-650.
22. 4. J. Invest. Dermatol. 84:1985;421-423.