Purifying a recalcitrant therapeutic recombinant protein with a mixed-mode chromatography sorbent

BioProcess International

Volumn 7, Issue 2, 2009, Pages 42-48

  Lees, Andrew ^a   Topping, Andrew ^b   Razzaq, Azzam ^b   Reiter, Karine ^c   Acosta, Alberto Lopez ^c  

^a Fina Biosolutions LLC   (United States)

^b Avecia Biologics Ltd   (United Kingdom)

^c Biosynexus Incorporated   (United States)

Author keywords

Chromatography; HCIC; HIC; IEX; IMAC; Mixed mode; Scale up; Sorbents

Indexed keywords

ANTIBODY; COBALT; COPPER; DNA; ENDOTOXIN; ENZYME; ESCHERICHIA COLI PROTEIN; NICKEL; POLYETHYLENEIMINE; RECOMBINANT PROTEIN; SORBENT; UNCLASSIFIED DRUG; ZINC; ZINC METALLOENZYME;

ACIDITY; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CHROMATOGRAPHY; CONTROLLED STUDY; DESORPTION; ELUTION; ENZYME ACTIVITY; HYDROPHILICITY; HYDROPHOBICITY; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IONIC STRENGTH; ISOELECTRIC POINT; MIXED MODE CHROMATOGRAPHY; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PURIFICATION; PROTEIN TARGETING;

EID: 77953377146     PISSN: 15426319     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (10)

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