Detection of glypican 3 in serum and its clinical significance on the diagnosis of hepatocellular carcinoma

Tumor

Volumn 27, Issue 9, 2007, Pages 679-682

  Zhou, Wei ^a   Guo, Xia ^a   Cao, Zhi Gang ^a   Zhao, Xin Tai ^a   Tu, Hong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Carcinoma, hepatocellular; Diagnostic techniques procedures; Engyme linked immunosorbent assay; Glypican 3

Indexed keywords

ALPHA FETOPROTEIN; GLYPICAN 3;

ARTICLE; CHRONIC HEPATITIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; LIVER CELL CARCINOMA; NORMAL VALUE; PROTEIN BLOOD LEVEL; RADIOIMMUNOASSAY; SENSITIVITY AND SPECIFICITY;

EID: 77953373162     PISSN: 10007431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. LOPEZ LJ, MARRERO J A. Hepatocellular carcinoma [J]. Curr Opin Gastroenterol, 2004,20(3):248-253.
2. Chinese source.
3. Chinese source.
4. ZHANG Z, COOMANS C, DAVID G, et al. Membrane heparan sulfate proteoglycan supported FGF2-FGFR signaling: evidence in support of the "cooperative and strutures" model [J]. J Biol Chem, 2001, 276(45):41921-41929.
5. HSU H C, CHENG W, LAI P L. Cloning and expression of a developmentally regulated transcript MXR7 in hepatocellular carcinoma: biological significance and temporospatial distribution [J]. Cancer Res, 1997,57(22):5179-5184.
6. GONZALEZ A D, KAYA M, SHI W, et al. OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner [J]. J Cell Biol, 1998,141:1407-1414.
7. SUNG Y K, HWANG S Y, PARK M K, et al. Glypican-3 is over-expressed in human hepatocellular carcinoma [J]. Cancer Sci, 2003,94(3): 259-262.
8. LLOVET JM, CHEN Y, WURMBACH E, et al. A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis[J]. Gastroenterology, 2006,131 (6): 1758-1767.
9. CAPURRO M, WANLESS I R, SHERMAN M, et al. Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma [J]. Gastroenterology, 2003, 125 (1): 89-97.
10. NAKATsURA T, YOSHITAKE, Y, SENJU S, et al. Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker[J]. Biochem Biophys Res Commun, 2003, 306(1):16-25.
11. HIPPO Y, WATANABE K, WATANABE AT, et al. Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma[J]. Cancer Res, 2004,64(7):2418-2423.
12. GEBO KA, CHANDER G, JENCKES MW, et al. Screening tests for hepatocellular carcinoma in patients with chronic hepatitis C: a systematic review[J]. Hepatology, 2002,36(5 Suppl):S84-92.
13. GUPTA S, BENT S, KOHLWES J. Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis c: a systematic review and critical analysis[J]. Ann Intern Med, 2003,139(1):46-50.
14. LIBBRECHT L, SEVERI T, CASSIMAN D, et al. Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules [J]. Am J Surg Pathol, 2006,30(11):1405-1411.