Novel process for the synthesis of Zaleplon

International Journal of ChemTech Research

Volumn 2, Issue 1, 2010, Pages 1-3

  Naik, Anil M ^a   Sawant, Shrikant D ^a   Kavishwar, Girish A ^a   Kavishwar, Smita G ^a  

^a Centaur Chemicals Pvt Ltd   (India)

Author keywords

3 amino 4 cyano pyrazole; N 3 (3 cyano pyrazolo 1, 5 a pyrimidin 7 yl) phenyl n ethyl acetamide; N 3 3 (dimethyl amino) 1 oxo 2 propenyl phenyl acetamide; N 3 3 (p chlorophenylamino) 1 oxo 2 propenyl phenyl n ethyl acetamide; Zaleplon

Indexed keywords

4 CHLOROANILINE; ACETAMIDE DERIVATIVE; BROMINE DERIVATIVE; HYDROCHLORIC ACID; N,N DIMETHYLFORMAMIDE; PYRAZOLE DERIVATIVE; SODIUM HYDROXIDE; TETRABUTYLAMMONIUM; ZALEPLON;

ARTICLE; CHEMICAL REACTION; DRUG QUALITY; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION TIME;

EID: 77953370981     PISSN: None     EISSN: 09744290     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Elie R; Rüther E, Farr I, Emilien G, Salinas E (Aug 1999). "Sleep latency is shortened during 4 weeks of treatment with zaleplon, a novel nonbenzodiazepine hypnotic. Zaleplon Clinical Study Group". J Clin Psychiatry: 536-44.
2. Menzin J, Lang KM, Levy P, Levy E (January 2001). "A general model of the effects of sleep medications on the risk and cost of motor vehicle accidents and its application to France". Pharmacoeconomics 19 (1): 69-78.
3. Vermeeren A, Riedel WJ, van Boxtel MP, Darwish M, Paty I, Patat A (March 2002). "Differential residual effects of zaleplon and zopiclone on actual driving: a comparison with a low dose of alcohol". Sleep 25 (2): 224-31.
4. Walsh JK; Pollak CP, Scharf MB, Schweitzer PK, Vogel GW (Jan-Feb 2000). "Lack of residual sedation following middle-of-the-night zaleplon administration in sleep maintenance insomnia". Clin Neuropharmacol 23: 17-21.
5. Walsh JK; Pollak CP, Scharf MB, Schweitzer PK, Vogel GW (Jan-Feb 2000). "Lack of residual sedation following middle-of-the-night zaleplon administration in sleep maintenance insomnia". Clin Neuropharmacol 23: 17-21.
6. Verster JC, Veldhuijzen DS, Volkerts ER (August 2004). "Residual effects of sleep medication on driving ability". Sleep Med Rev 8 (4): 309-25.
7. Barbera J, Shapiro C (2005). "Benefit-risk assessment of zaleplon in the treatment of insomnia". Drug Saf 28 (4): 301-18.