Tanghinigenin from seeds of Cerbera manghas L. induces apoptosis in human promyelocytic leukemia HL-60 cells

Environmental Toxicology and Pharmacology

Volumn 30, Issue 1, 2010, Pages 31-36

  Wang, Guo Fei ^a   Guo, Yue Wei ^b   Feng, Bo ^a   Li, Liang ^b   Huang, Cai Guo ^a   Jiao, Bing Hua ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Apoptosis; Caspase; Fas; FasL; HL 60; Tanghinigenin

Indexed keywords

CARDIAC GLYCOSIDE; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS LIGAND; TANGHINIGENIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CERBERA MANGHAS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEDICINAL PLANT; PLANT SEED; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

CERBERA MANGHAS;

EID: 77953363633     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2010.03.012     Document Type: Article

References (24)

1. Friesen C., Herr I., Krammer P.H., Debatin K.M. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat. Med. 1996, 2:574-577.
2. Fulda S., Sieverts H., Friesen C., Herr I., Debatin K.M. The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res. 1997, 57:3823-3829.
3. Gratas C., Tohma Y., Barnas C., Taniere P., Hainaut P., Ohgaki H. Up-regulation of Fas (APO-1/CD95) ligand and downregulation of Fas expression in human esophageal cancer. Cancer Res. 1998, 58:2057-2062.
4. Hamad E., Mather P.J., Srinivasan S., Rubin S., Whellan D.J., Feldman A.M. Pharmacologic therapy of chronic heart failure. Am. J. Cardiovasc. Drugs 2007, 7:235-248.
5. Itoh N., Yonehara S., Ishii A., Yonehara M., Mizushima S., Sameshima M., Hase A., Seto Y., Nagata S. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991, 66:233-243.
6. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997, 91:479-489.
7. Li J., Zelenin S., Aperia A., Aizman O. Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-κB. JASN 2006, 17:1848-1857.
8. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays. J. Immunol. Methods 1983, 65:55-63.
9. Muller M., Strand S., Hug H., Heinemann E.M., Walczak H., Hofmann W.J., Stremmel W., Krammer P.H., Galle P.R. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wildtype p53. J. Clin. Invest. 1997, 99:403-413.
10. Muzio M., Stockwell B.R., Stennicke H.R., Salvesen G.S., Dixit V.M. An induced proximity model for caspase-8 activation. J. Biol. Chem. 1998, 273:2926-2930.
11. Nelson A., Juan C.D., Olga S., Harvey B.P. Heart failure drug digitoxin induces calcium uptake into cells by forming transmembrane calcium channels. PNAS 2008, 105:2610-2615.
12. Pitrak D.L., Tsai H.C., Mullane K.M., Sutton S.H., Stevens P. Accelerated neutrophil apoptosis in the acquired immunodeficiency syndrome. J. Clin. Invest. 1996, 98:2714-2719.
13. Robert A., Newman, Yang P.Y., Alison D., Pawlus, Keith I., BlocK Cardiac glycosides as novel cancer therapeutic agents. Mol. Interv. 2008, 8:36-49.
14. Salvesen G.S., Dixit V.M. Caspases: intracellular signaling by proteolysis. Cell 1997, 91443-91446.
15. Salvesen G.S., Dixit V.M. Caspase activation: the induced-proximity model. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:10964-10967.
16. Scaffidi C., Fulda S., Srinivasan A., Friesen C., Li F., Tomaselli K.J., Debatin K.M., Krammer P.H., Peter M.E. Two CD95 (Apo-1/Fas) signaling pathways. EMBO J. 1998, 17(6):1675-1687.
17. Schempp C.M., Simon-Haarhaus B., Termeer C.C., Simon J.C. Hypericin photo-induced apoptosis involves the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and activation of caspase-8. FEBS Lett. 2001, 493:26-30.
18. Schulze-Osthoff K., Ferrari D., Los M., Wesselborg S., Peter M.E. Apoptosis signaling by death receptors. Eur. J. Biochem. 1998, 254:439-459.
19. Stenkvist B. Cardenolides and cancer. Anticancer Drugs 2001, 12:635-636.
20. Tillman D.M., Petak I., Houghton J.A. A fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells. Clin. Cancer Res. 1999, 5:425-430.
21. Trauth B.C., Klas C., Peters A.M., Matzku S., Moller P., Falk W., Debatin K.M., Krammer P.H. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989, 245:301-305.
22. Trevisi L., Visentin B., Cusinato F., Pighin I., Luciani S. Antiapoptotic effect of ouabain in human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun. 2004, 321:716-721.
23. Wilhelm S., Georgios S.B. Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth. AJP-Cell Physiol. 2007, 293:C509-C536.
24. Yamauchi T., Abe F., Wan A.S.C. Studies on cerbera V minor glycosides of 17-alpha digitoxigenin from the stems of genus Cerbera. Chem. Pharm. Bull. 1987, 35:4993-4995.