Adjuvant chemotherapy in elderly patients with colorectal cancer. A retrospective analysis of the implementation of tumor board recommendations in a single institution

Critical Reviews in Oncology/Hematology

Volumn 74, Issue 3, 2010, Pages 211-217

  Kurtz, Jean Emmanuel ^a   Heitz, Damien ^a   Serra, Sebastian ^a   Brigand, Cécile ^a   Juif, Vanessa ^a   Podelski, Valérie ^a   Meyer, Pierre ^b   Litique, Valère ^a   Bergerat, Jean Pierre ^a   Rohr, Serge ^a   Dufour, Patrick ^c  

^a UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c CENTRE PAUL STRAUSS   (France)

Author keywords

Adjuvant chemotherapy; Colorectal cancer; Elderly

Indexed keywords

CAPECITABINE; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN;

AGED; BLOOD TOXICITY; CANCER ADJUVANT THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; COLORECTAL CANCER; COMORBIDITY; CONTINUOUS INFUSION; DRUG TOLERABILITY; DRUG WITHDRAWAL; EMERGENCY SURGERY; FEBRILE NEUTROPENIA; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; PERIPHERAL NEUROPATHY; PROGRESSION FREE SURVIVAL; REVIEW; TUMOR LOCALIZATION;

AGED; ANTINEOPLASTIC AGENTS; CHEMOTHERAPY, ADJUVANT; COLORECTAL NEOPLASMS; COMBINED MODALITY THERAPY; HUMANS; RETROSPECTIVE STUDIES;

EID: 77953359926     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2009.05.003     Document Type: Review

References (19)

1. Ciccolallo L., Capocaccia R., Coleman M.P., et al. Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis and surgery. Gut 2005, 54:268-273.
2. Martijn H., Voogd A.C., van de Poll-Franse L.V., et al. Improved survival of patients with rectal cancer since 1980: a population-based study. Eur J Cancer 2003, 39:2073-2079.
3. Kurtz J.E., Andrès E., Natarajan-Amé S., Noel E., Dufour P. Oral chemotherapy in colorectal cancer treatment: review of the literature. Eur J Intern Med 2003, 14:18-25.
4. Sargent D., Sobrero A., Grothey A., et al. Evidence for cure by adjuvant therapy in colon cancer: observations based on individual patient data from 20,898 patients on 18 randomized trials. J Clin Oncol 2009, 27:872-877.
5. Monnet E., Faivre J., Raymond L., Garau I. Influence of stage at diagnosis on survival differences for rectal cancer in three European populations. Br J Cancer 1999, 81:463-468.
6. Aparicio T., Navazesh A., Boutron I., et al. Half of elderly patients routinely treated for colorectal cancer receive a sub-standard treatment. Crit Rev Oncol Hematol 2009, [Epub ahead of print].
7. Schrag D., Cramer L.D., Bach P.B., Begg C.B. Age and adjuvant chemotherapy use after surgery for stage III colon cancer. J Natl Cancer Inst 2001, 93:850-857.
8. Rougier P., Mitry E., Aranda E., Daniele B., Labianca R., Carrato A. Elderly colorectal cancer patients are undertreated. Eur J Cancer 2004, 2:8-13.
9. Sargent D.J., Goldberg R.M., Jacobson S.D., et al. A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med 2001, 345:1091-1097.
10. Van Cutsem E.D.J., Oliveira J. Colon cancer: ESMO clinical recommendations for diagnosis, adjuvant treatment and follow-up. Ann Oncol 2008, 19(Suppl. 2):ii29-ii30.
11. Bouvier AM. Epidémiologie descriptive du cancer colorectal en France. Accessed April 3, 2009. http://www.invs.sante.fr/beh/2009/02_03/beh_02_03_2009.pdf.
12. Golfinopoulos V., Pentheroudakis G., Pavlidis N. Treatment of colorectal cancer in the elderly: a review of the literature. Cancer Treat Rev 2006, 32:1-8.
13. André T., Boni C., Mounedji-Boudiaf L., et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004, 350:2343-2351.
14. Zeber J.E., Copeland L.A., Hosek B.J., Karnad A.B., Lawrence V.A., Sanchez-Reilly S.E. Cancer rates, medical comorbidities, and treatment modalities in the oldest patients. Crit Rev Oncol Hematol 2008, 67:237-242.
15. Kurtz J.E., Heitz D., Enderlin P., et al. Geriatric oncology, general practitioners and specialists. Current opinions and unmet needs. Crit Rev Oncol Hematol 2009, 10.1016/j.critrevonc.2009.03.002.
16. Neugut A.I., Matasar M., Wang X., et al. Duration of adjuvant chemotherapy for colon cancer and survival among the elderly. J Clin Oncol 2006, 24:2368-2375.
17. Scheithauer W., McKendrick J., Begbie S., et al. Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial. Ann Oncol 2003, 14:1735-1743.
18. Papamichael D., Audisio R., Horiot J.C., et al. Treatment of the elderly colorectal cancer patients: SIOG expert recommendations. Ann Oncol 2009, 20:5-16.
19. Gross C.P., MacAvay G.J., Guo Z., Tinetti M.E. The impact of chronic illness on the uses and effectiveness of adjuvant chemotherapy for colon cancer. Cancer 2007, 109:2410-2419.