Platelet proinflammatory activity in clinically stable patients with CF starts in early childhood

Journal of Cystic Fibrosis

Volumn 9, Issue 3, 2010, Pages 179-186

  Sturm, Alexander ^a   Hebestreit, Helge ^a   Koenig, Corinne ^a   Walter, Ulrich ^b   Grossmann, Ralf ^b  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CD40 LIGAND; FIBRINOGEN RECEPTOR; L SELECTIN; PROCOAGULANT; CYTOKINE; PADGEM PROTEIN;

ADOLESCENT; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL COLONIZATION; BLOOD CLOTTING; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DOWN REGULATION; EXOCYTOSIS; HUMAN; INFLAMMATION; LEUKOCYTE AGGREGATION; MONOCYTE; NEUTROPHIL COUNT; PROTEIN BLOOD LEVEL; PSEUDOMONAS AERUGINOSA; SCHOOL CHILD; STAPHYLOCOCCUS AUREUS; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; ADULT; AGE; BLOOD; CASE CONTROL STUDY; IMMUNOLOGY; LEUKOCYTE; METABOLISM; PATHOPHYSIOLOGY; PRESCHOOL CHILD; THROMBOCYTE; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; BLOOD PLATELETS; CASE-CONTROL STUDIES; CD40 LIGAND; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; CYTOKINES; HUMANS; INFLAMMATION; LEUKOCYTES; P-SELECTIN; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; YOUNG ADULT;

EID: 77953359393     PISSN: 15691993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcf.2009.12.004     Document Type: Article

References (29)

1. Gibson R.L., Bruns J.L., Ramsey B.W. Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 2003, 168:918-915.
2. Armstrong D.S., Grimwood K., Carlin J.B., et al. Lower airway inflammation in infants and young children with cystic fibrosis. Am J Respir Crit Care Med 1997, 156:1197-1204.
3. Konstan M.W., Berger M. Current understanding of the inflammatory process in cystic fibrosis: onset and etiology. Pediatr Pulmonol 1997, 24:137-142.
4. Gawaz M., Langer H., May E. Platelets in inflammation and atherogenesis. J Clin Invest 2005, 115:3378-3384.
5. O'Sullivan B.P., Linden M.D., Frelinger A.L., et al. Platelet activation in cystic fibrosis. Blood 2005, 105:4635-4641.
6. Da Costa Martins P., Zwaginga J.J. Leukocyte-platelet aggregates: new particles reflecting and effecting cardiovascular disease. Thromb Haemost 2005, 94:1120-1121.
7. Pitchford S.C., Yano H., Lever R., et al. Platelets are essential for leukocyte recruitment in allergic inflammation. J Allergy Clin Immunol 2003, 112:109-118.
8. Smith C., Marlin S., Rothlein R., Toman C., Anderson D.C. Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J Clin Invest 1989, 83:2008-2017.
9. Evangelista V., Manarini S., Sideri R., et al. Platelet/polymorphonuclear leukocyte interaction: P-selectin triggers protein-tyrosine phosphorylation-dependent CD11b/CD18 adhesion: role of PSGL-1 as a signalling molecule. Blood 1999, 93:876-885.
10. Irving P.M., Macey M.G., Shah U., Webb L., Lanmead L., Rampton D.S. Formation of platelet-leukocyte aggregates in inflammatory bowel disease. Inflamm Bowel Dis 2004, 10:361-372.
11. Falco A., Romano M., Iapichino L., Collura M., Davi G. Increased soluble CD40 ligand levels in cystic fibrosis. J Thromb Haemost 2004, 2:557-560.
12. O'Sullivan B.P., Michelson A.D. The inflammatory role of platelets in cystic fibrosis. Am J Respir Crit Care Med 2006, 173:483-490.
13. Hodson M.E., Morris L., Batten J.C. Serum immunoglobulins and immunoglobulin G subclasses in cystic fibrosis related to the clinical state of the patient. Eur Respir J 1988, 1:701-705.
14. Wheeler W.B., Williams M., Matthews W.J., Colten H.R. Progression of cystic fibrosis lung disease as a function of serum immunoglobulin G levels: a 5-year longitudinal study. J Pediatr 1984, 104:696-699.
15. Watkin S.L., Elborn J.S., Cordon S.M., Hiller E.J., Shale D.J. C-reactive protein is not a useful indicator of intermittent bacterial colonization in early lung disease of patients with cystic fibrosis. Pediatr Pulmonol 1994, 17:6-10.
16. Woollard K.J., Kling D., Kulkarni S., Dart A.M., Jackson S., Chin-Dusting J. Raised plasma soluble P-selectin in peripheral arterial occlusive disease enhances leukocyte adhesion. Circ Res 2006, 98:149-156.
17. Henn V., Slupsky J.R., Gräfe M., et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature 1998, 391:591-594.
18. McEver R.P. Selectins. Curr Opin Immunol 1994, 6:75-84.
19. Nagasawa M., Zhu Y., Isoda T., et al. Analysis of serum soluble CD40 ligand (sCD40L) in the patients undergoing allogenic stem cell transplantation: platelet is a major source of serum sCD40L. Eur J Haematol 2005, 74:54-60.
20. Gurbel P.A., Kereiakes D.J., Serebruany V.L. Soluble P-selectin is not a surrogate marker for platelet P-selectin: evidence from a multicenter chest pain study group. J Thromb Thrombolysis 2000, 10:15-22.
21. Michelson A.D., Barnard M.R., Hechtman H.B., et al. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci 1996, 93:11877-11882.
22. Furman M.I., Benoit S.E., Barnard M.R., et al. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol 1998, 31:352-358.
23. 2, in coronary stenting. Thromb Res 2003, 111:171-177.
24. Konig B., Jaeger K., Sage A., Vasil M., Konig W. Role of Pseudomonas aeruginose lipase in inflammatory mediator release from human inflammatory effector cells (platelets, granulocytes, and monocytes). Infect Immun 1996, 64:3252-3285.
25. Yaguchi A., Lobo F.L., Vincent J.L., Pradier O. Platelet function in sepsis. J Thromb Haemost 2004, 2:2096-2102.
26. Holthe M.R., Staff A.C., Berge L.N., Lyberg T. Different levels of platelet activation in preeclamptic, normotensive pregnant, and nonpregnant women. Am J Obst Gynecol 2004, 190:1128-1134.
27. Konstan M.W., Byard P.J., Hoppel C.L., Davis P.B. Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med 1995, 332:848-854.
28. Davi G., Iapichino L., Balsamo V., et al. Thromboxane biosynthesis and pulmonary function in cystic fibrosis. Adv Prostaglandin Thromboxane Leukot Res 1995, 23:369-371.
29. Ciabattoni G., Davi G., Collura M., et al. In vivo peroxidation and platelet activation in cystic fibrosis. Am J Respir Crit Care Med 2000, 162:1195-1201.