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Volumn 57, Issue 2-3, 2010, Pages 146-156

Human health risk assessment of pharmaceuticals in water: An uncertainty analysis for meprobamate, carbamazepine, and phenytoin

Author keywords

Human health; Pharmaceuticals; Risk assessment; Toxicity; Uncertainty

Indexed keywords

CARBAMAZEPINE; DRINKING WATER; MEPROBAMATE; PHENYTOIN;

EID: 77953356803     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2010.02.002     Document Type: Article
Times cited : (85)

References (50)
  • 3
    • 41949098620 scopus 로고    scopus 로고
    • Human health risk assessments for three neuropharmaceutical compounds in surface waters
    • Bercu J.P., Parke N.J., Fiori J.M., Meyerhoff R.D. Human health risk assessments for three neuropharmaceutical compounds in surface waters. Regul. Toxicol. Pharmacol. 2008, 50:420-427.
    • (2008) Regul. Toxicol. Pharmacol. , vol.50 , pp. 420-427
    • Bercu, J.P.1    Parke, N.J.2    Fiori, J.M.3    Meyerhoff, R.D.4
  • 4
    • 61349186332 scopus 로고    scopus 로고
    • Uncertainty characterization approaches for risk assessment of DBPs in drinking water: a review
    • Chowdhury S., Champagne, Mc.Lellan P.J. Uncertainty characterization approaches for risk assessment of DBPs in drinking water: a review. J. Environ. Mgmt. 2009, 90:1680-1691.
    • (2009) J. Environ. Mgmt. , vol.90 , pp. 1680-1691
    • Chowdhury, S.1    Champagne2    Mc.Lellan, P.J.3
  • 5
    • 0032459770 scopus 로고    scopus 로고
    • Pharmaceuticals in the environment - a human risk?
    • Christensen F.M. Pharmaceuticals in the environment - a human risk?. Regul. Toxicol. Pharmacol. 1998, 28:212-221.
    • (1998) Regul. Toxicol. Pharmacol. , vol.28 , pp. 212-221
    • Christensen, F.M.1
  • 6
    • 1642393941 scopus 로고    scopus 로고
    • Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid
    • Cleuvers M. Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid. Ecotoxicol. Environ. Saf. 2004, 59:309-315.
    • (2004) Ecotoxicol. Environ. Saf. , vol.59 , pp. 309-315
    • Cleuvers, M.1
  • 7
    • 43849096292 scopus 로고    scopus 로고
    • Preliminary risk assessment database and risk ranking of pharmaceuticals in the environment
    • Cooper E.R., Siewicki T.C., Phillips K. Preliminary risk assessment database and risk ranking of pharmaceuticals in the environment. Sci. Tot. Environ. 2008, 398(1-3):26-33.
    • (2008) Sci. Tot. Environ. , vol.398 , Issue.1-3 , pp. 26-33
    • Cooper, E.R.1    Siewicki, T.C.2    Phillips, K.3
  • 8
    • 58749109763 scopus 로고    scopus 로고
    • Human health risk assessment from the presence of human pharmaceuticals in the aquatic environment
    • Cunningham V.L., Binks S.P., Olson M.J. Human health risk assessment from the presence of human pharmaceuticals in the aquatic environment. Regul. Toxicol. Pharmacol. 2009, 53:39-45.
    • (2009) Regul. Toxicol. Pharmacol. , vol.53 , pp. 39-45
    • Cunningham, V.L.1    Binks, S.P.2    Olson, M.J.3
  • 9
    • 39649114776 scopus 로고    scopus 로고
    • Risk of gastrointestinal disease associated with exposure to pathogens in the water of the Lower Passaic River
    • Donovan E., Unice K., Roberts J.D., Harris M., Finley B. Risk of gastrointestinal disease associated with exposure to pathogens in the water of the Lower Passaic River. Appl. Environ. Microbiol. 2008, 74(4):994-1003.
    • (2008) Appl. Environ. Microbiol. , vol.74 , Issue.4 , pp. 994-1003
    • Donovan, E.1    Unice, K.2    Roberts, J.D.3    Harris, M.4    Finley, B.5
  • 10
    • 33845421594 scopus 로고    scopus 로고
    • Water ingestion during swimming activities in a pool: a pilot study
    • Dufour A.P., Evans O., Behymer T.D., Cantu R. Water ingestion during swimming activities in a pool: a pilot study. J. Water Health 2006, 4:425-430.
    • (2006) J. Water Health , vol.4 , pp. 425-430
    • Dufour, A.P.1    Evans, O.2    Behymer, T.D.3    Cantu, R.4
  • 13
    • 77953358713 scopus 로고    scopus 로고
    • Hazardous substance data bank (HSDB). Available from: . Accessed December.
    • Hazardous substance data bank (HSDB), 2009. Available from: Accessed December 1, 2009. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB.
    • (2009) , vol.1
  • 14
    • 0034735832 scopus 로고    scopus 로고
    • Folic acid antagonists during pregnancy and the risk of birth defects
    • Hernandez-Diaz S., Werler M.M., Walker A.M., Mitchell Folic acid antagonists during pregnancy and the risk of birth defects. N. Engl. J. Med. 2000, 343(22):1608-1614.
    • (2000) N. Engl. J. Med. , vol.343 , Issue.22 , pp. 1608-1614
    • Hernandez-Diaz, S.1    Werler, M.M.2    Walker, A.M.3    Mitchell4
  • 15
    • 0035873403 scopus 로고    scopus 로고
    • Neutral tube defects in relation to use of folic acid antagonists during pregnancy
    • Hernandez-Diaz S., Werler M.M., Walker A.M., Mitchell Neutral tube defects in relation to use of folic acid antagonists during pregnancy. Am. J. Epidemiol. 2001, 153(10):961-968.
    • (2001) Am. J. Epidemiol. , vol.153 , Issue.10 , pp. 961-968
    • Hernandez-Diaz, S.1    Werler, M.M.2    Walker, A.M.3    Mitchell4
  • 16
    • 41649095306 scopus 로고    scopus 로고
    • Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study
    • Johnson A.C., Jurgens M.D., Williams R.J., Kummerer K., Kortenkamp A., Sumpter J.P. Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study. J. Hydrol. 2008, 348:167-175.
    • (2008) J. Hydrol. , vol.348 , pp. 167-175
    • Johnson, A.C.1    Jurgens, M.D.2    Williams, R.J.3    Kummerer, K.4    Kortenkamp, A.5    Sumpter, J.P.6
  • 17
    • 15044359596 scopus 로고    scopus 로고
    • Pharmaceuticals: a threat to drinking water?
    • Jones O.A., Lester J.N., Voulvoulis N. Pharmaceuticals: a threat to drinking water?. Trends Biotechnol. 2005, 23(4):163-167.
    • (2005) Trends Biotechnol. , vol.23 , Issue.4 , pp. 163-167
    • Jones, O.A.1    Lester, J.N.2    Voulvoulis, N.3
  • 18
    • 0037085574 scopus 로고    scopus 로고
    • Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance
    • Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 2002, 36:1202-1211.
    • (2002) Environ. Sci. Technol. , vol.36 , pp. 1202-1211
    • Kolpin, D.W.1    Furlong, E.T.2    Meyer, M.T.3    Thurman, E.M.4    Zaugg, S.D.5    Barber, L.B.6    Buxton, H.T.7
  • 19
    • 77953362254 scopus 로고    scopus 로고
    • Arsenic exposure in U.S. public and domestic drinking water supplies: a comparative risk assessment
    • Kumar A., Adak P., Gurian P.L., Lockwood J.R. Arsenic exposure in U.S. public and domestic drinking water supplies: a comparative risk assessment. J. Expo. Sci. Environ. Epidemiol 2009, 1-10.
    • (2009) J. Expo. Sci. Environ. Epidemiol , pp. 1-10
    • Kumar, A.1    Adak, P.2    Gurian, P.L.3    Lockwood, J.R.4
  • 20
    • 0033037957 scopus 로고    scopus 로고
    • Improve method for estimating bioconcentration/bioaccumulation factor for octanol/water partition coefficient
    • Meylan W.M., Howerd P.H., Boethling R.S., Aronson D., Printup H., Gouchie S. Improve method for estimating bioconcentration/bioaccumulation factor for octanol/water partition coefficient. Environ. Toxicol. Chem. 1999, 18:664-672.
    • (1999) Environ. Toxicol. Chem. , vol.18 , pp. 664-672
    • Meylan, W.M.1    Howerd, P.H.2    Boethling, R.S.3    Aronson, D.4    Printup, H.5    Gouchie, S.6
  • 21
    • 18944375566 scopus 로고    scopus 로고
    • SCRAM: a scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes-resulting chemical scores and ranking
    • Mitchell R.R., Summer C.L., Blonde S.A., Bush D.M., Hurlburt G.K., Snyder E.M., Giesy J.P. SCRAM: a scoring and ranking system for persistent, bioaccumulative, and toxic substances for the North American Great Lakes-resulting chemical scores and ranking. Hum. Ecol. Risk Assess. 2002, 8(3):537-557.
    • (2002) Hum. Ecol. Risk Assess. , vol.8 , Issue.3 , pp. 537-557
    • Mitchell, R.R.1    Summer, C.L.2    Blonde, S.A.3    Bush, D.M.4    Hurlburt, G.K.5    Snyder, E.M.6    Giesy, J.P.7
  • 23
    • 55649113302 scopus 로고    scopus 로고
    • Ranking potential impacts of priority and emerging pollutants in urban wastewater through life cycle impact assessment
    • Munoz I., Gomez M.J., Molina-Diaz A., Huijbregts M.A.J., Fernandez-Alba A.R., Garcia-Calvo E. Ranking potential impacts of priority and emerging pollutants in urban wastewater through life cycle impact assessment. Chemosphere 2008, 74:37-44.
    • (2008) Chemosphere , vol.74 , pp. 37-44
    • Munoz, I.1    Gomez, M.J.2    Molina-Diaz, A.3    Huijbregts, M.A.J.4    Fernandez-Alba, A.R.5    Garcia-Calvo, E.6
  • 24
    • 77953356300 scopus 로고    scopus 로고
    • National Toxicology Program (NTP) 2000. NTP technical report on the toxicity studies of Carisprodol (CAS No.) administered by gavage to f344/N rats and B6CF1 mice. Available from: . Accessed January.
    • National Toxicology Program (NTP) 2000. NTP technical report on the toxicity studies of Carisprodol (CAS No. 78-44-4) administered by gavage to f344/N rats and B6CF1 mice. Available from: . Accessed January 4, 2010. http://ntp.niehs.nih.gov/ntp/htdocs/ST_rpts/tox056.pdf.
    • (2010) , vol.4 , Issue.4 , pp. 78-44
  • 27
    • 39149130698 scopus 로고    scopus 로고
    • Effects and interactions in an environmentally relevant mixture of pharmaceuticals
    • Pomati F., Orlandi C., Clerici M., Luciani F., Zuccato E. Effects and interactions in an environmentally relevant mixture of pharmaceuticals. Toxicol. Sci. 2008, 102(1):129-137.
    • (2008) Toxicol. Sci. , vol.102 , Issue.1 , pp. 129-137
    • Pomati, F.1    Orlandi, C.2    Clerici, M.3    Luciani, F.4    Zuccato, E.5
  • 28
    • 73449147015 scopus 로고    scopus 로고
    • Cytotoxic drugs in drinking water: a prediction and risk assessment exercise for the Thames catchment in the United Kingdom
    • Rowney N.C., Johnson A.C., Williams R.J. Cytotoxic drugs in drinking water: a prediction and risk assessment exercise for the Thames catchment in the United Kingdom. Environ. Toxicol. Chem. 2009, 28(12):2733-2743.
    • (2009) Environ. Toxicol. Chem. , vol.28 , Issue.12 , pp. 2733-2743
    • Rowney, N.C.1    Johnson, A.C.2    Williams, R.J.3
  • 29
    • 67349220456 scopus 로고    scopus 로고
    • Runoff of pharmaceuticals and personal care products following application of dewatered municipal biosolids to an agricultural field
    • Sabourin L., Beck A., Duenik P.W., Kleywegt S., Lapen D.R., Li H., Metcalfe C.D., Payne M., Topp E. Runoff of pharmaceuticals and personal care products following application of dewatered municipal biosolids to an agricultural field. Sci. Total. Environ. 2009, 407:4596-4604.
    • (2009) Sci. Total. Environ. , vol.407 , pp. 4596-4604
    • Sabourin, L.1    Beck, A.2    Duenik, P.W.3    Kleywegt, S.4    Lapen, D.R.5    Li, H.6    Metcalfe, C.D.7    Payne, M.8    Topp, E.9
  • 31
    • 0032747235 scopus 로고    scopus 로고
    • Antiepileptic drug regimens and major congenital abnormalities in the offspring
    • Samren E.B., van Duijn C.M., Christiaens G.C., Hofman A., Lindhout D. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann. Neurol. 1999, 46(5):739-746.
    • (1999) Ann. Neurol. , vol.46 , Issue.5 , pp. 739-746
    • Samren, E.B.1    van Duijn, C.M.2    Christiaens, G.C.3    Hofman, A.4    Lindhout, D.5
  • 35
    • 77953361164 scopus 로고    scopus 로고
    • SCR PhysProp Database. Interactive physProp database demo. Available from: . Accessed July.
    • SCR PhysProp Database., 2009. Interactive physProp database demo. Available from: . Accessed July 26, 2009. http://www.srcinc.com/what-we-do/databaseforms.aspx?id=386.
    • (2009) , vol.26
  • 36
    • 0037090577 scopus 로고    scopus 로고
    • Something from " Nothing" - Eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects
    • Silva E., Rajapakse N., Kortenkamp A. Something from " Nothing" - Eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects. Environ. Sci. Technol. 2002, 36:1751-1756.
    • (2002) Environ. Sci. Technol. , vol.36 , pp. 1751-1756
    • Silva, E.1    Rajapakse, N.2    Kortenkamp, A.3
  • 38
    • 40349090187 scopus 로고    scopus 로고
    • Occurrence, treatment, and toxicological relevance of EDCs and pharmaceuticals in water
    • Snyder S.A. Occurrence, treatment, and toxicological relevance of EDCs and pharmaceuticals in water. Ozone: Sci. Eng. 2008, 30:65-69.
    • (2008) Ozone: Sci. Eng. , vol.30 , pp. 65-69
    • Snyder, S.A.1
  • 41
    • 3242680822 scopus 로고    scopus 로고
    • Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant
    • Stackelberg P.E., Furlong E.T., Myer M.T., Zuagg S.D., Henderon A.K., Reissman D.B. Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant. Sci. Tot. Environ. 2004, 329:99-113.
    • (2004) Sci. Tot. Environ. , vol.329 , pp. 99-113
    • Stackelberg, P.E.1    Furlong, E.T.2    Myer, M.T.3    Zuagg, S.D.4    Henderon, A.K.5    Reissman, D.B.6
  • 42
    • 34247472979 scopus 로고    scopus 로고
    • Efficiency of conventional drinking-water-treatment processes in removal of pharmaceuticals and other organic compounds
    • Stackelberg P.E., Gibs J., Furlong E.T., Meyer M.T., Zaugg S.D., Lippincott R.L. Efficiency of conventional drinking-water-treatment processes in removal of pharmaceuticals and other organic compounds. Sci. Total. Environ. 2007, 377:255-272.
    • (2007) Sci. Total. Environ. , vol.377 , pp. 255-272
    • Stackelberg, P.E.1    Gibs, J.2    Furlong, E.T.3    Meyer, M.T.4    Zaugg, S.D.5    Lippincott, R.L.6
  • 43
    • 77953355994 scopus 로고    scopus 로고
    • United States Environmental Protection Agency (U.S. EPA). Exposure factors handbook. EPA/600/P-95/002Fa.
    • United States Environmental Protection Agency (U.S. EPA), 1997. Exposure factors handbook. EPA/600/P-95/002Fa.
    • (1997)
  • 44
    • 77953358143 scopus 로고    scopus 로고
    • US EPA. Setting standards for safe drinking water. Available from: . Accessed December 2009.
    • US EPA, 2006. Setting standards for safe drinking water. Available from: . Accessed December 2, 2009. http://www.epa.gov/ogwdw/standard/setting.html.
    • (2006) , vol.2
  • 45
    • 77953360418 scopus 로고    scopus 로고
    • US EPA. Available from: . Accessed February.
    • US EPA, 2009. Available from: . Accessed February 26, 2009. http://www.epa.gov/risk/health-risk.htm.
    • (2009) , Issue.26
  • 46
    • 57349196516 scopus 로고    scopus 로고
    • Ranking of pharmaceuticals detected in the environment: aggregation and weighting procedures
    • Voigt K., Bruggemann R. Ranking of pharmaceuticals detected in the environment: aggregation and weighting procedures. Comb. Chem. High Throughput Screen. 2008, 11:770-782.
    • (2008) Comb. Chem. High Throughput Screen. , vol.11 , pp. 770-782
    • Voigt, K.1    Bruggemann, R.2
  • 47
    • 0037447750 scopus 로고    scopus 로고
    • Indirect human exposure to pharmaceuticals via drinking water
    • Webb S., Ternes T., Gibert M., Olejniczak K. Indirect human exposure to pharmaceuticals via drinking water. Toxicol. Lett. 2003, 142:157-167.
    • (2003) Toxicol. Lett. , vol.142 , pp. 157-167
    • Webb, S.1    Ternes, T.2    Gibert, M.3    Olejniczak, K.4
  • 48
    • 24644507816 scopus 로고    scopus 로고
    • Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes
    • Westerhoff P., Yoon Y., Shane S., Wert E. Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes. Environ. Sci. Technol. 2005, 39:6649-6663.
    • (2005) Environ. Sci. Technol. , vol.39 , pp. 6649-6663
    • Westerhoff, P.1    Yoon, Y.2    Shane, S.3    Wert, E.4
  • 49
    • 60849133978 scopus 로고    scopus 로고
    • Evaluation of public health risks at recreational beaches in Lake Michigan via detection of enteric viruses and a human-specific bacteriological marker
    • Wong M., Kumar L., Jenkins T.M., Xagoraraki, Phanikumar M.S., Rose J.B. Evaluation of public health risks at recreational beaches in Lake Michigan via detection of enteric viruses and a human-specific bacteriological marker. Water Res. 2009, 43:1137-1149.
    • (2009) Water Res. , vol.43 , pp. 1137-1149
    • Wong, M.1    Kumar, L.2    Jenkins, T.M.3    Xagoraraki4    Phanikumar, M.S.5    Rose, J.B.6
  • 50
    • 77953360597 scopus 로고    scopus 로고
    • Water pollution: emerging contaminants associated with drinking water
    • Academic Press, San Diego, K. Heggenhougen, S. Quah (Eds.)
    • Xagoraraki I., Kuo D. Water pollution: emerging contaminants associated with drinking water. International Encyclopedia of Public Health 2008, 539-550. Academic Press, San Diego. K. Heggenhougen, S. Quah (Eds.).
    • (2008) International Encyclopedia of Public Health , pp. 539-550
    • Xagoraraki, I.1    Kuo, D.2


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