Preparation and evaluation of carnauba wax microspheres loaded with aceclofenac for controlled release

Indian Journal of Pharmaceutical Education and Research

Volumn 42, Issue 4, 2008, Pages 329-336

  Gowda, D V ^a   Girish, B ^a   Shivakumar, H G ^a   Moin, Afrasin ^a  

^a JSS COLLEGE OF PHARMACY   (India)

Author keywords

Aceclofenac; Controlled release; Release kinetics; Wax microsphere

Indexed keywords

ACECLOFENAC; ALTRAFLAM SR; CARNAUBA WAX MICROSPHERE; MICROSPHERE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; COOLING; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG DOSAGE FORM COMPARISON; DRUG RELEASE; EMULSION; IN VITRO STUDY; INFRARED SPECTROSCOPY; SCANNING ELECTRON MICROSCOPY;

EID: 77953350083     PISSN: 00195464     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Burkhard Heinz, Thomas Rau, Daniel Werner. Aceclofenac spares cyclooxygenase - 1 as a result of limited but sustained biotransformation to diclofenac. Clin Pharmcol Ther 2003; 74: 22-27.
2. Jeaehwi Lee, Yoonjin Lee, Jongseok Kim, Mikyeong, Young Wook Choi. Formulation of Micro emulsion Systems for transdermal delivery of aceclofenac. Arch Pharm Res 2005; 28(9): 1097-102.
3. James Swarbrick, James C Boylan. Microsphere technology and applications. Encyclopedia of Pharmaceutical Technology. New York: Marcel Dekker; 1994.
4. Joseph R Robinson, Vincent HL Lee. Controlled drug delivery. Fundamentals and Applications. New York: Marcel Dekker; 1987.
5. Tomlinson E, Burger JJ, McVie JG, Hoefnagel K. Recent Advances in drug delivery systems. New York: Plenum; 1984.
6. Patrick B Deasy. Microencapsulation and related drug processes. NewYork: Marcel Dekker; 1984.
7. Luigi Tessari, Luciano Ceciliani, Albert Belluti. Aceclofenac cream versus piroxicam cream in the treatment of patients with minor traumas and phlogistic inffections of soft tissues: A doubleblind study. Currrent Ther Res. 1995; 66(7): 702-12.
8. Schawartz JB, Simonelli AP, Higuchi WI. Drug release from wax matrices: Analysis of data with first order kinetics and with the diffusion controlled model. J Pharma Sci. 1968; 57: 274-77.
9. Kibbe AH. Handbook of Pharmaceutical Excipents. 3rd ed. London: Association Of Pharmaceutical society of Great Britain; 2000.
10. Bennet H. Industrial waxes, natural and synthetic waxes. 4th ed. NewYork: Chemical Publishing Company; 1975.
11. Presser Lima PV, Fontanella V. Analgesic efficacy of aceclofenac after surgical extraction of impacted lower third molars. Int J Oral Maxillofac Surg 2006; 302: 78-83.
12. Chul Soon Yong A, Yu Kyoung Ohb, Kyung Hee Lee C. Trials of clear aceclofenac-loaded soft capsules with accelerated oral absorption in human subjects. Int J Pharm 2005; 302: 78-83.
13. Giannola LI, De Caro V, Rizzo MC. Preparation of white beeswax microspheres loaded with valproic acid and kinetic study of drug release. Drug Dev Ind Pharm. 1995; 21 (7):793-07.
14. Giannola L I, De Caro V, Severino. Carnauba wax microspheres loaded with with valproic acid: preparation and evaluation of drug release. Drug Dev Ind Pharm. 1995; 21: 1563-72.
15. Sah H. Micro encapsulation techniques using ethyl acetate as dispersed solvent effect its extraction rate on the characterstic of PLGA microspheres. J Controlled R, 1997; 7: 223-38.
16. Gowda DV. Shivakumar HG. Encapsulation of griseofulvin in waxes/fat microspheres: preparation, characterization and release kineticsof microspheres. Indian drugs. 2005; 42 (7): 453-60.
17. Gowda D V. Shivakumar HG. Preparation and evaluation of waxes/fat microspheres loaded with lithium carbonate for controlled release. Indian J Pharm Sci. 2007; 69(2):251-56.
18. Muthalik, Naha A, Anusha, Rajith AK, Musmade P. preparation, in vitro pre clinical evaluation of once daily sustained release tablets of Aceclofenac. Arch Pharm Res.2007; 30 (2): 222-34.
19. Dahiya P, Pathak K.Influence of amorphous cyclodextrin derivative on Aceclofenac release from directly compressible tablets. Pharmazie 2007; 62 (4):278-83.