Improved mechanical properties of hydroxyapatite/poly(ε-caprolactone) scaffolds by surface modification of hydroxyapatite

Applied Surface Science

Volumn 256, Issue 20, 2010, Pages 6107-6112

  Wang, Yan ^a   Dai, Jing ^a   Zhang, Qingchun ^a   Xiao, Yan ^a   Lang, Meidong ^a  

^a East China University of Science and Technology   (China)

Author keywords

Hydroxyapatite; Mechanical property; Poly( caprolactone); Scaffold; Surface grafting

Indexed keywords

FOURIER TRANSFORM INFRARED SPECTROSCOPY; FOURIER TRANSFORMS; GRAFTING (CHEMICAL); GRAVIMETRIC ANALYSIS; HYDROXYAPATITE; MECHANICAL PROPERTIES; NANOPARTICLES; PHASE SEPARATION; SURFACE TREATMENT; THERMOGRAVIMETRIC ANALYSIS; X RAY DIFFRACTION;

CAPROLACTONE; FOURIER TRANSFORMATIONS; HYDROXYAPATITE (HAP); LEACHING TECHNIQUES; POLY (EPSILONCAPROLACTONE); SURFACE GRAFTING; THERMAL GRAVIMETRIC ANALYSES (TGA); THERMALLY INDUCED PHASE SEPARATION;

SCAFFOLDS;

EID: 77953325379     PISSN: 01694332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apsusc.2010.03.127     Document Type: Article

References (40)

1. Karageorgiou V., and Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26 (2005) 5474-5491
2. Ma P.X., Zhang R.Y., Xiao G.Z., and Franceschi R. Engineering new bone tissue in vitro on highly porous poly(α-hydroxyl acids)/hydroxyapatite composite scaffolds. J. Biomed. Mater. Res. 54 (2001) 284-293
3. Jung Y., Kim S.S., Kim Y.H., Kim S.H., Kim B.S., Kim S., Choi C.Y., and Kim S.H. A poly(lactic acid)/calcium metaphosphate composite for bone tissue engineering. Biomaterials 26 (2005) 6314-6322
4. Pattison M.A., Wurster S., Webster T.J., and Haberstroh K.M. Three-dimensional, nano-structured PLGA scaffolds for bladder tissue replacement applications. Biomaterials 26 (2005) 2491-2500
5. Causa F., Netti P.A., Ambrosio L., Ciapetti G., Baldini N., Pagani S., Martini D., and Giunti A. Poly-ε-caprolactone/hydroxyapatite composites for bone regeneration: in vitro characterization and human osteoblast response. J. Biomed. Mater. Res. 76A (2006) 151-162
6. Hao J.Y., Yuan M.L., and Deng X.M. Biodegradable and biocompatible nanocomposites of poly(ε-caprolactone) with hydroxyapatite nanocrystals: thermal and mechanical properties. J. Appl. Polym. Sci. 86 (2002) 676-683
7. Pitt C.G., Chasalow F.I., Hibionada Y.M., Klimas D.M., and Schindler A. Aliphatic polyesters. I. The degradation of poly(ε-caprolactone) in vivo. J. Appl. Polym. Sci. 26 (1981) 3779-3787
8. Ali S.A.M., Zhong S.P., Doherty P.J., and Williams D.F. Mechanisms of polymer degradation in implantable devices. I. Poly(caprolactone). Biomaterials 14 (1993) 648-656
9. Ciapetti G., Ambrosio L., Savarino L., Granchi D., Cenni E., Baldini N., Pagani S., Guizzardi S., Causa F., and Giunti A. Osteoblast growth and function in porous poly ε-caprolactone matrices for bone repair: a preliminary study. Biomaterials 24 (2003) 3815-3824
10. Rizzi S.C., Heath D.J., Coombes A.G.A., Bock N., Textor M., and Downes S. Biodegradable polymer/hydroxyapatite composites: surface analysis and initial attachment of human osteoblasts. J. Biomed. Mater. Res. 55 (2001) 475-486
11. Wei G.B., and Ma P.X. Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for bone tissue engineering. Biomaterials 25 (2004) 4749-4757
12. Yu H.Y., Matthew H.W., Wooley P.H., and Yang S.Y. Effect of porosity and pore size on microstructures and mechanical properties of poly-ε-caprolactone-hydroxyapatite composites. J. Biomed. Mater. Res., Part B: Appl. Biomater. 86B (2008) 541-547
13. Hong Z.K., Reis R.L., and Mano J.F. Preparation and in vitro characterization of scaffolds of poly(l-lactic acid) containing bioactive glass ceramic nanoparticles. Acta Biomater. 4 (2008) 1297-1306
14. Kim S.S., Park M.S., Jeon O., Choi C.Y., and Kim B.S. Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering. Biomaterials 27 (2006) 1399-1409
15. Koh Y.H., Jun I.K., and Kim H.E. Fabrication of poly(ε-caprolactone)/hydroxyapatite scaffold using rapid direct deposition. Mater. Lett. 60 (2006) 1184-1187
16. Zhang R.Y., and Ma P.X. Poly(α-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology. J. Biomed. Mater. Res. 44 (1999) 446-455
17. Xiao X.F., Liu R.F., and Huang Q.Y. Preparation and characterization of nano-hydroxyapatite/polymer composite scaffolds. J. Mater. Sci.: Mater. Med. 19 (2008) 3429-3435
18. Yang Y.F., Zhao J., Zhao Y.H., Wen L., Yuan X.Y., and Fan Y.B. Formation of porous PLGA scaffolds by a combining method of thermally induced phase separation and porogen leaching. J. Appl. Polym. Sci. 109 (2008) 1232-1241
19. Borum-Nicholas L., and Wilson Jr. O.C. Surface modifi{ligature}cation of hydroxyapatite. Part I. Dodecyl alcohol. Biomaterials 24 (2003) 3671-3679
20. Borum L., and Wilson Jr. O.C. Surface modifi{ligature}cation of hydroxyapatite. Part II. Silica. Biomaterials 24 (2003) 3681-3688
21. Tanaka H., Futaoka M., Hino R., Kandori K., and Ishikawa T. Structure of synthetic calcium hydroxyapatite particles modified with pyrophosphoric acid. J. Colloid Interface Sci. 283 (2005) 609-612
22. Matsuda A., Furuzono T., Walsh D., Kishida A., and Tanaka J. Surface modification of a porous hydroxyapatite to promote bonded polymer coatings. J. Mater. Sci.: Mater. Med. 14 (2003) 973-978
23. Qiu X.Y., Hong Z.K., Hu J.L., Chen L., Chen X.S., and Jing X.B. Hydroxyapatite surface modified by l-lactic acid and its subsequent grafting polymerization of l-lactide. Biomacromolecules 6 (2005) 1193-1199
24. Nichols H.L., Zhang N., Zhang J., Shi D.L., Bhaduri S., and Wen X.J. Coating nanothickness degradable fi{ligature}lms on nanocrystalline hydroxyapatite particles to improve the bonding strength between nanohydroxyapatite and degradable polymer matrix. J. Biomed. Mater. Res. 82A (2007) 372-382
25. Rai B., Noohom W., Kithva P.H., Grøndahl L., and Matt Trau. Bionanohydroxyapatite/poly(3-hydroxybutyrate-co-3-hydroxyvalerate) composites with improved particle dispersion and superior mechanical properties. Chem. Mater. 20 (2008) 2802-2808
26. Chen M.F., Tan J.J., Lian Y.Y., and Liu D.B. Preparation of gelatin coated hydroxyapatite nanorods and the stability of its aqueous colloidal. Appl. Surf. Sci. 254 (2008) 2730-2735
27. Li J., Lu X.L., and Zheng Y.F. Effect of surface modifi{ligature}ed hydroxyapatite on the tensile property improvement of HA/PLA composite. Appl. Surf. Sci. 255 (2008) 494-497
28. Lee H.J., Choi H.W., Kim K.J., and Lee S.C. Modification of hydroxyapatite nanosurfaces for enhanced colloidal stability and improved interfacial adhesion in nanocomposites. Chem. Mater. 18 (2006) 5111-5118
29. Gong X.H., Tang C.Y., Hu H.C., Zhou X.P., and Xie X.L. Improved mechanical properties of HIPS/hydroxyapatite composites by surface modification of hydroxyapatite via in-situ polymerization of styrene. J. Mater. Sci.: Mater. Med. 15 (2004) 1141-1146
30. Lee S.C., Choi H.W., Lee H.J., Kim K.J., Chang J.H., Kim S.Y., Choi J., Oh K.S., and Jeong Y.K. In-situ synthesis of reactive hydroxyapatite nano-crystals for a novel approach of surface grafting polymerization. J. Mater. Chem. 17 (2007) 174-180
31. Kothapalli C.R., Shaw M.T., and Wei M. Biodegradable HA-PLA 3-D porous scaffolds: effect of nano-sized filler content on scaffold properties. Acta Biomater. 1 (2005) 653-662
32. Wunderlich B. Macromolecular Physics, Vol. 3, Crystal Melting (1980), Academic Press, New York
33. Kannan S., Lemos A.F., and Ferreira J.M.F. Synthesis and mechanical performance of biological-like hydroxyapatites. Chem. Mater. 18 (2006) 2181-2186
34. Chang M.C., and Tanaka J. FT-IR study for hydroxyapatite/collagen nanocomposite cross-linked by glutaraldehyde. Biomaterials 23 (2002) 4811-4818
35. Hong Z.K., Qiu X.Y., Sun J.R., Deng M.X., Chen X.S., and Jing X.B. Grafting polymerization of l-lactide on the surface of hydroxyapatite nano-crystals. Polymer 45 (2004) 6699-6706
36. Helwig E., Sandner B., Gopp U., Vogt F., Wartewig S., and Henning S. Ring-opening polymerization of lactones in the presence of hydroxyapatite. Biomaterials 22 (2001) 2695-2702
37. Choi H.W., Lee H.J., Kim K.J., Kim H.M., and Lee S.C. Surface modification of hydroxyapatite nanocrystals by grafting polymers containing phosphonic acid groups. J. Colloid Interface Sci. 304 (2006) 277-281
38. Hou Q.P., Grijpma D.W., and Feijen J. Porous polymeric structures for tissue engineering prepared by a coagulation, compression moulding and salt leaching technique. Biomaterials 24 (2003) 1937-1947
39. Liu A.X., Hong Z.K., Zhuang X.L., Chen X.S., Cui Y., Liu Y., and Jing X.B. Surface modification of bioactive glass nanoparticles and the mechanical and biological properties of poly(l-lactide) composites. Acta Biomater. 4 (2008) 1005-1015
40. 2 nanoparticles: synthesis and characterization. Eur. Polym. J. 44 (2008) 2476-2481