Chromatin structure and the formation of chromosomal alterations

Chromosomal Alterations: Methods, Results and Importance in Human Health

Volumn 9783540714149, Issue , 2007, Pages 201-209

  Kreth, Gregor ^a   Cremer, Christoph ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77953292204     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-540-71414-9_12     Document Type: Chapter

References (13)

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2. Bolzer A, Kreth G, Solovei I, Koehler D, Saracoglu K, Fauth C, Müller S, Eils R, Cremer C, Speicher M, Cremer T (2005) Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol 3:e157
3. Boyle S, Gilchrist S, Bridger JM, Mahy NL, Ellis JA, Bickmore WA (2001) The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum Mol Genet 10:211-219
4. Branco MR, Pombo A (2006) Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLOS Biol 4:e138
5. Cornforth MN, Greulich-Bode KM, Loucas BD, Arsuaga J, Vazquez M, Sachs RK, Bruckner M, Molls M, Hahnfeldt P, Hlatky L, Brenner DJ (2002) Chromosomes are predominantly located randomly with respect to each other in interphase human cells. J Cell Biol 159:237-244
6. Cremer M, von Hase J, Volm T, Brero A, Kreth G, Walter J, Fischer C, Solovei I, Cremer C, Cremer T (2001) Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res 9:541-567
7. Eils R, Dietzel S, Bertin E, Granzow M, Schröck E, Speicher MR, Volm T, Ried T, Robert-Nicoud M, Cremer C, Cremer T (1996) Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X-chromosome territories have similar volumes but differ in shape and surface structure. J Cell Biol 135:1427-1440
8. Kreth G, Münkel C, Langowski J, Cremer T, Cremer C (1998) Chromatin structure and chromosome aberrations: modeling of damage induced by isotropic and localized irradiation. Mutat Res 404:77-88
9. Kreth G, Edelmann P, Münkel C, Langowski J, Cremer C (2002) Translocation frequencies for X and Y chromosomes predicted by computer simulations of nuclear structure. In: Sobti RC, Obe G, Athwal RS (eds) Some aspects of chromosome structure and functions. Narosa, New Delhi, pp 57-71
10. Kreth G, Finsterle J, Cremer C (2004) Virtual radiation biophysics: implications of nuclear structure. Cytogenet Genome Res 104:157-161
11. Kreth G, Pazhanisamy SK, Hausmann M, Cremer C (2007) Cell type specific quantitative predictions of radiation-induced chromosome aberrations: a computer mode approach. Radiat Res (in press)
12. Tanabe H, Müller S, Neusser M, von Hase J, Calcagno E, Cremer M, Solovei I, Cremer C, Cremer T (2002) Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc Natl Acad Sci USA 99:4424-4429
13. Tanaka K, Kamada N, Ohkita T, Kuramoto A (1983) Nonrandom distribution of chromosome breaks in lymphocytes of atomic bomb survivors. J Radiat Res 24:291-304