메뉴 건너뛰기




Volumn 63, Issue 1, 2010, Pages 52-62

Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne

Author keywords

acne vulgaris; benzoyl peroxide; clindamycin; combination benzoyl peroxide clindamycin; meta analysis; salicylic acid

Indexed keywords

BENZOYL PEROXIDE; CLINDAMYCIN; PLACEBO; SALICYLIC ACID;

EID: 77953287828     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2009.07.052     Document Type: Article
Times cited : (61)

References (28)
  • 1
  • 2
    • 44249099060 scopus 로고    scopus 로고
    • Practical considerations in acne treatment and the clinical impact of topical combination therapy
    • Krakowski A., Stendardo S., and Eichenfield L. Practical considerations in acne treatment and the clinical impact of topical combination therapy. Pediatr Dermatol 25 Suppl (2008) 1-14
    • (2008) Pediatr Dermatol , vol.25 , Issue.SUPPL , pp. 1-14
    • Krakowski, A.1    Stendardo, S.2    Eichenfield, L.3
  • 3
    • 51149087253 scopus 로고    scopus 로고
    • Antibiotic use in acne vulgaris and rosacea: clinical considerations and resistance issues of significance to dermatologists
    • Del Rosso J.Q., Leyden J.J., Thiboutot D., and Webster G.F. Antibiotic use in acne vulgaris and rosacea: clinical considerations and resistance issues of significance to dermatologists. Cutis 82 Suppl (2008) 5-12
    • (2008) Cutis , vol.82 , Issue.SUPPL , pp. 5-12
    • Del Rosso, J.Q.1    Leyden, J.J.2    Thiboutot, D.3    Webster, G.F.4
  • 4
    • 43149085296 scopus 로고    scopus 로고
    • Emerging topical antimicrobial options for mild-to-moderate acne: a review of the clinical evidence
    • Del Rosso J. Emerging topical antimicrobial options for mild-to-moderate acne: a review of the clinical evidence. J Drugs Dermatol 7 Suppl (2008) S2-S7
    • (2008) J Drugs Dermatol , vol.7 , Issue.SUPPL
    • Del Rosso, J.1
  • 5
    • 0035051738 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of a combination topical gel formulation of benzoyl peroxide and clindamycin with benzoyl peroxide, clindamycin and vehicle gel in the treatments of acne vulgaris
    • Leyden J.J., Berger R.S., Dunlap F.E., Ellis C.N., Connolly M.A., and Levy S.F. Comparison of the efficacy and safety of a combination topical gel formulation of benzoyl peroxide and clindamycin with benzoyl peroxide, clindamycin and vehicle gel in the treatments of acne vulgaris. Am J Clin Dermatol 2 (2001) 33-39
    • (2001) Am J Clin Dermatol , vol.2 , pp. 33-39
    • Leyden, J.J.1    Berger, R.S.2    Dunlap, F.E.3    Ellis, C.N.4    Connolly, M.A.5    Levy, S.F.6
  • 6
    • 0030874150 scopus 로고    scopus 로고
    • Treatment of acne with a combination clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel: combined results of two double-blind investigations
    • Lookingbill D.P., Chalker D.K., Lindholm J.S., Katz H.I., Kempers S.E., Huerter C.J., et al. Treatment of acne with a combination clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel: combined results of two double-blind investigations. J Am Acad Dermatol 37 (1997) 590-595
    • (1997) J Am Acad Dermatol , vol.37 , pp. 590-595
    • Lookingbill, D.P.1    Chalker, D.K.2    Lindholm, J.S.3    Katz, H.I.4    Kempers, S.E.5    Huerter, C.J.6
  • 7
    • 53349103001 scopus 로고    scopus 로고
    • An aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for the once-daily treatment of moderate to severe acne vulgaris: assessment of efficacy and safety in 2813 patients
    • Thiboutot D., Zaenglein A., Weiss J., Webster G., Calvarese B., and Chen D. An aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for the once-daily treatment of moderate to severe acne vulgaris: assessment of efficacy and safety in 2813 patients. J Am Acad Dermatol 59 (2008) 792-800
    • (2008) J Am Acad Dermatol , vol.59 , pp. 792-800
    • Thiboutot, D.1    Zaenglein, A.2    Weiss, J.3    Webster, G.4    Calvarese, B.5    Chen, D.6
  • 8
    • 35648951759 scopus 로고    scopus 로고
    • Topical clindamycin in the management of acne vulgaris
    • Guay D.R. Topical clindamycin in the management of acne vulgaris. Expert Opin Pharmacother 8 (2007) 2625-2664
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 2625-2664
    • Guay, D.R.1
  • 9
    • 77953294013 scopus 로고    scopus 로고
    • A comparison of a novel benzoyl peroxide system with a combination benzoyl peroxide and clindamycin product: A 2-week split-face study of effectiveness and tolerability
    • Poster presented at: February 2-6, Washington, DC
    • Wilson DC, Meadows KP, Ramirez J. A comparison of a novel benzoyl peroxide system with a combination benzoyl peroxide and clindamycin product: a 2-week split-face study of effectiveness and tolerability. Poster presented at: 65th Annual Meeting of the American Academy of Dermatology; February 2-6, 2007; Washington, DC.
    • (2007) 65th Annual Meeting of the American Academy of Dermatology
    • Wilson, D.C.1    Meadows, K.P.2    Ramirez, J.3
  • 10
    • 70349312543 scopus 로고    scopus 로고
    • A 3-step acne system containing solubilized benzoyl peroxide versus clindamycin-benzoyl peroxide
    • Thiboutot D., Eichenfield L., Shalita A., Del Rosso J.Q., Swinyer L., Tanghetti E., et al. A 3-step acne system containing solubilized benzoyl peroxide versus clindamycin-benzoyl peroxide. Cutis 84 (2009) 48-55
    • (2009) Cutis , vol.84 , pp. 48-55
    • Thiboutot, D.1    Eichenfield, L.2    Shalita, A.3    Del Rosso, J.Q.4    Swinyer, L.5    Tanghetti, E.6
  • 11
    • 47249131549 scopus 로고    scopus 로고
    • Solubilized benzoyl peroxide versus benzoyl peroxide/clindamycin in the treatment of moderate acne
    • Tanghetti E., Kircik L., Wilson D., and Dhawan S. Solubilized benzoyl peroxide versus benzoyl peroxide/clindamycin in the treatment of moderate acne. J Drugs Dermatol 7 (2008) 534-538
    • (2008) J Drugs Dermatol , vol.7 , pp. 534-538
    • Tanghetti, E.1    Kircik, L.2    Wilson, D.3    Dhawan, S.4
  • 12
    • 70349327580 scopus 로고    scopus 로고
    • Comparing a novel solubilized benzoyl peroxide gel with benzoyl peroxide/clindamycin: final data from a multicenter, investigator-blind, randomized study
    • Kircik L., Green L., Thiboutot D., Tanghetti E., Wilson D., Dhawan S., and Parr L. Comparing a novel solubilized benzoyl peroxide gel with benzoyl peroxide/clindamycin: final data from a multicenter, investigator-blind, randomized study. J Drugs Dermatol 8 (2009) 812-818
    • (2009) J Drugs Dermatol , vol.8 , pp. 812-818
    • Kircik, L.1    Green, L.2    Thiboutot, D.3    Tanghetti, E.4    Wilson, D.5    Dhawan, S.6    Parr, L.7
  • 13
    • 77953293033 scopus 로고    scopus 로고
    • Evaluation of a novel acne treatment system (CLENZIderm MD) designed to enhance the efficacy of benzoyl peroxide treatment: An investigator-blind, randomized study
    • Poster presented at: March 3-9, Maui, HI
    • Wilson DC. Evaluation of a novel acne treatment system (CLENZIderm MD) designed to enhance the efficacy of benzoyl peroxide treatment: an investigator-blind, randomized study. Poster presented at: 31st Hawaii Dermatology Seminar; March 3-9, 2007; Maui, HI.
    • (2007) 31st Hawaii Dermatology Seminar
    • Wilson, D.C.1
  • 14
    • 0035260887 scopus 로고    scopus 로고
    • A combination benzoyl peroxide and clindamycin topical gel compared with benzoyl peroxide, clindamycin phosphate, and vehicle in the treatment of acne vulgaris
    • Tschen E.H., Katz H.I., Jones T.M., Monroe E.W., Kraus S.J., Connolly M.A., et al. A combination benzoyl peroxide and clindamycin topical gel compared with benzoyl peroxide, clindamycin phosphate, and vehicle in the treatment of acne vulgaris. Cutis 67 (2001) 165-169
    • (2001) Cutis , vol.67 , pp. 165-169
    • Tschen, E.H.1    Katz, H.I.2    Jones, T.M.3    Monroe, E.W.4    Kraus, S.J.5    Connolly, M.A.6
  • 15
    • 0034954923 scopus 로고    scopus 로고
    • The efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product
    • Leyden J.J., Hickman J.G., Jarratt M.T., Stewart D.M., and Levy S.F. The efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product. J Cutan Med Surg 5 (2001) 37-42
    • (2001) J Cutan Med Surg , vol.5 , pp. 37-42
    • Leyden, J.J.1    Hickman, J.G.2    Jarratt, M.T.3    Stewart, D.M.4    Levy, S.F.5
  • 16
    • 77953290447 scopus 로고    scopus 로고
    • FDA, Center for Drug Evaluation and Research. Medical Review of NDA 50-741. Study 152.
    • FDA, Center for Drug Evaluation and Research. Medical Review of NDA 50-741. Study 152.
  • 17
    • 77953288577 scopus 로고    scopus 로고
    • FDA, Center for Drug Evaluation and Research. Medical Review of NDA 50-741. Study 156.
    • FDA, Center for Drug Evaluation and Research. Medical Review of NDA 50-741. Study 156.
  • 18
    • 0141750409 scopus 로고    scopus 로고
    • New therapy update-A unique combination formulation in the treatment of inflammatory acne
    • Fagundes D.S., Fraser J.M., and Klauda H.C. New therapy update-A unique combination formulation in the treatment of inflammatory acne. Cutis 72 suppl (2003) 16-19
    • (2003) Cutis , vol.72 , Issue.SUPPL , pp. 16-19
    • Fagundes, D.S.1    Fraser, J.M.2    Klauda, H.C.3
  • 19
    • 36849046694 scopus 로고    scopus 로고
    • A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide and adapalene in the treatment of mild to moderate facial acne vulgaris
    • Langner A., Chu A., Goulden V., and Ambroziak M. A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide and adapalene in the treatment of mild to moderate facial acne vulgaris. Br J Dermatol 158 (2008) 122-129
    • (2008) Br J Dermatol , vol.158 , pp. 122-129
    • Langner, A.1    Chu, A.2    Goulden, V.3    Ambroziak, M.4
  • 20
    • 33846959462 scopus 로고    scopus 로고
    • A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide (Duac) and erythromycin + zinc acetate (Zineryt) in the treatment of mild to moderate facial acne vulgaris
    • Langner A., Sheehan-Dare R., and Layton A. A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide (Duac) and erythromycin + zinc acetate (Zineryt) in the treatment of mild to moderate facial acne vulgaris. J Eur Acad Dermatol Venereol 21 (2007) 311-319
    • (2007) J Eur Acad Dermatol Venereol , vol.21 , pp. 311-319
    • Langner, A.1    Sheehan-Dare, R.2    Layton, A.3
  • 21
    • 27144433558 scopus 로고    scopus 로고
    • Comparison of clindamycin/benzoyl peroxide, tretinoin plus clindamycin, and the combination of clindamycin/benzoyl peroxide and tretinoin plus clindamycin in the treatment of acne vulgaris: a randomized, blinded study
    • Bowman S., Gold M., Nasir A., and Vamvakias G. Comparison of clindamycin/benzoyl peroxide, tretinoin plus clindamycin, and the combination of clindamycin/benzoyl peroxide and tretinoin plus clindamycin in the treatment of acne vulgaris: a randomized, blinded study. J Drugs Dermatol 4 (2005) 611-618
    • (2005) J Drugs Dermatol , vol.4 , pp. 611-618
    • Bowman, S.1    Gold, M.2    Nasir, A.3    Vamvakias, G.4
  • 22
    • 0025977791 scopus 로고
    • A comparison of the effectiveness of topical tetracycline, benzoyl-peroxide gel and oral oxytetracycline in the treatment of acne
    • Norris J.F., Hughes B.R., Basey A.J., and Cunliffe W.J. A comparison of the effectiveness of topical tetracycline, benzoyl-peroxide gel and oral oxytetracycline in the treatment of acne. Clin Exp Dermatol 16 (1991) 31-33
    • (1991) Clin Exp Dermatol , vol.16 , pp. 31-33
    • Norris, J.F.1    Hughes, B.R.2    Basey, A.J.3    Cunliffe, W.J.4
  • 23
    • 0023760387 scopus 로고
    • A comparative study of benzoyl peroxide and clindamycin phosphate for treating acne vulgaris
    • Swinyer L.J., Baker M.D., Swinyer T.A., and Mills Jr. O.H. A comparative study of benzoyl peroxide and clindamycin phosphate for treating acne vulgaris. Br J Dermatol 119 (1988) 615-622
    • (1988) Br J Dermatol , vol.119 , pp. 615-622
    • Swinyer, L.J.1    Baker, M.D.2    Swinyer, T.A.3    Mills Jr., O.H.4
  • 24
    • 29244481461 scopus 로고    scopus 로고
    • Two randomized, double-blind, controlled trials of 2219 subjects to compare the combination clindamycin/tretinoin hydrogel with each agent alone and vehicle for the treatment of acne vulgaris
    • Leyden J.J., Krochmal L., and Yaroshinsky A. Two randomized, double-blind, controlled trials of 2219 subjects to compare the combination clindamycin/tretinoin hydrogel with each agent alone and vehicle for the treatment of acne vulgaris. J Am Acad Dermatol 54 (2006) 73-81
    • (2006) J Am Acad Dermatol , vol.54 , pp. 73-81
    • Leyden, J.J.1    Krochmal, L.2    Yaroshinsky, A.3
  • 25
    • 0041326627 scopus 로고    scopus 로고
    • Efficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clindamycin: a multicenter, randomized, investigator-blinded study
    • Wolf Jr. J.E., Kaplan D., Kraus S.J., Loven K.H., Rist T., Swinyer L.J., et al. Efficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clindamycin: a multicenter, randomized, investigator-blinded study. J Am Acad Dermatol 49 suppl (2003) S211-S217
    • (2003) J Am Acad Dermatol , vol.49 , Issue.SUPPL
    • Wolf Jr., J.E.1    Kaplan, D.2    Kraus, S.J.3    Loven, K.H.4    Rist, T.5    Swinyer, L.J.6
  • 26
    • 0033806179 scopus 로고    scopus 로고
    • A multicentre, single-blind, randomized comparison of a fixed clindamycin phosphate/tretinoin gel formulation (Velac) applied once daily and a clindamycin lotion formulation (Dalacin T) applied twice daily in the topical treatment of acne vulgaris
    • Zouboulis C.C., Derumeaux L., Decroix J., Maciejewska-Udziela B., Cambazard F., and Stuhlert A. A multicentre, single-blind, randomized comparison of a fixed clindamycin phosphate/tretinoin gel formulation (Velac) applied once daily and a clindamycin lotion formulation (Dalacin T) applied twice daily in the topical treatment of acne vulgaris. Br J Dermatol 143 (2000) 498-505
    • (2000) Br J Dermatol , vol.143 , pp. 498-505
    • Zouboulis, C.C.1    Derumeaux, L.2    Decroix, J.3    Maciejewska-Udziela, B.4    Cambazard, F.5    Stuhlert, A.6
  • 27
    • 10644287732 scopus 로고    scopus 로고
    • A successful maintenance approach in inflammatory acne with adapalene gel 0.1% after an initial treatment in combination with clindamycin topical solution 1% or after monotherapy with clindamycin topical solution 1%
    • Zhang J.Z., Li L.F., Tu Y.T., and Zheng J. A successful maintenance approach in inflammatory acne with adapalene gel 0.1% after an initial treatment in combination with clindamycin topical solution 1% or after monotherapy with clindamycin topical solution 1%. J Dermatolog Treat 15 (2004) 372-378
    • (2004) J Dermatolog Treat , vol.15 , pp. 372-378
    • Zhang, J.Z.1    Li, L.F.2    Tu, Y.T.3    Zheng, J.4
  • 28
    • 17544362634 scopus 로고    scopus 로고
    • The safety and efficacy of clindamycin phosphate foam 1% versus clindamycin phosphate topical gel 1% for the treatment of acne vulgaris
    • Clindamycin Foam Study Group
    • Shalita A.R., Myers J.A., Krochmal L., Yaroshinsky A., and Clindamycin Foam Study Group. The safety and efficacy of clindamycin phosphate foam 1% versus clindamycin phosphate topical gel 1% for the treatment of acne vulgaris. J Drugs Dermatol 4 (2005) 48-56
    • (2005) J Drugs Dermatol , vol.4 , pp. 48-56
    • Shalita, A.R.1    Myers, J.A.2    Krochmal, L.3    Yaroshinsky, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.