Enzymatic quantification of cholesterol and cholesterol esters from silicone hydrogel contact lenses

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 6, 2010, Pages 2949-2954

  Pucker, Andrew D ^a   Thangavelu, Mirunalni ^a   Nichols, Jason J ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROFORM; CHOLESTEROL; CHOLESTEROL ESTER; CHOLESTEROL OLEATE; GALYFILCON A; LOTRAFILCON B; METHANOL; SILICON; UNCLASSIFIED DRUG; SILICONE DERIVATIVE;

ADULT; ARTICLE; CALIBRATION; CONTACT LENS; CONTROLLED STUDY; ENZYME MECHANISM; EX VIVO STUDY; EXTRACTION; FEMALE; HUMAN; HUMAN EXPERIMENT; HYDROGEL; IN VITRO STUDY; LIPID ANALYSIS; MALE; NORMAL HUMAN; PRIORITY JOURNAL; CHEMISTRY; ENZYME ASSAY; HYDROPHILIC CONTACT LENS; PROSPECTIVE STUDY;

ADULT; CHOLESTEROL; CHOLESTEROL ESTERS; CONTACT LENSES, HYDROPHILIC; ENZYME ASSAYS; FEMALE; HUMANS; HYDROGELS; MALE; PROSPECTIVE STUDIES; SILICONES;

EID: 77953265569     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-3368     Document Type: Article

References (38)

1. McCulley JP, Shine W. A compositional based model for the tear film lipid layer. Trans Am Ophthalmol Soc. 1997;95:79-88, discussion 88-93.
2. Butovich IA. Cholesteryl esters as a depot for very long chain fatty acids in human meibum. J Lipid Res. 2009;50:501-513.
3. Ham BM, Jacob JT, Keese MM, Cole RB. Identification, quantification and comparison of major non-polar lipids in normal and dry eye tear lipidomes by electrospray tandem mass spectrometry. J Mass Spectrom. 2004;39:1321-1336.
4. Shine WE, McCulley JP. Polar lipids in human meibomian gland secretions. Curr Eye Res. 2003;26:89-94.
5. Tiffany JM. The lipid secretion of the meibomian glands. Adv Lipid Res. 1987;22:1-62.
6. Nichols KK, Ham BM, Nichols JJ, Ziegler C, Green-Church KB. Identification of fatty acids and fatty acid amides in human meibomian gland secretions. Invest Ophthalmol Vis Sci. 2007;48:34-39.
7. Iwata S, Lemp MA, Holly FJ, Dohlman CH. Evaporation rate of water from the precorneal tear film and cornea in the rabbit. Invest Ophthalmol. 1969;8:613-619.
8. Craig JP, Tomlinson A. Importance of the lipid layer in human tear film stability and evaporation. Optom Vis Sci. 1997;74:8-13.
9. Mathers WD, Lane JA. Meibomian gland lipids, evaporation, and tear film stability. Adv Exp Med Biol. 1998;438:349-360.
10. King-Smith PE, Fink BA, Nichols JJ, Nichols KK, Braun RJ, McFadden GB. The contribution of lipid layer movement to tear film thinning and breakup. Invest Ophthalmol Vis Sci. 2009;50:2747-2756.
11. King-Smith PE, Nichols JJ, Nichols KK, Fink BA, Braun RJ. Contributions of evaporation and other mechanisms to tear film thinning and break-up. Optom Vis Sci. 2008;85:623-630.
12. Andrews JS. Human tear film lipids. I. Composition of the principal non-polar component. Exp Eye Res. 1970;10:223-227.
13. Andrews JS. The Meibomian secretion. Int Ophthalmol Clin. 1973; 13:23-28.
14. van Haeringen NJ, Glasius E. Cholesterol in human tear fluid. Exp Eye Res. 1975;20:271-274.
15. Tiffany JM. Individual variations in human meibomian lipid composition. Exp Eye Res. 1978;27:289-300.
16. Tiffany JM. The meibomian lipids of the rabbit. I. Overall composition. Exp Eye Res. 1979;29:195-202.
17. Nicolaides N, Kaitaranta JK, Rawdah TN, Macy JI, Boswell FM 3rd, Smith RE. Meibomian gland studies: comparison of steer and human lipids. Invest Ophthalmol Vis Sci. 1981;20:522-536.
18. Nicolaides N, Ruth EC. Unusual fatty acids in the lipids of steer and human meibomian gland excreta. Curr Eye Res. 1982;2:93-98.
19. Tiffany JM, Marsden RG. The meibomian lipids of the rabbit. II. Detailed composition of the principal esters. Exp Eye Res. 1982; 34:601-608.
20. Harvey DJ, Tiffany JM, Duerden JM, Pandher KS, Mengher LS. Identification by combined gas chromatography-mass spectrometry of constituent long-chain fatty acids and alcohols from the meibomian glands of the rat and a comparison with human meibomian lipids. J Chromatogr. 1987;414:253-263.
21. Nicolaides N, Santos EC, Smith RE, Jester JV. Meibomian gland dysfunction. III. Meibomian gland lipids. Invest Ophthalmol Vis Sci. 1989;30:946-951.
22. Wollensak G, Mur E, Mayr A, Baier G, Gottinger W, Stoffler G. Effective methods for the investigation of human tear film proteins and lipids. Graefes Arch Clin Exp Ophthalmol. 1990;228:78-82.
23. Greiner JV, Glonek T, Korb DR, Booth R, Leahy CD. Phospholipids in meibomian gland secretion. Ophthalmic Res. 1996;28:44-49.
24. Prager MD, Quintana RP. Radiochemical studies on contact lens soilation. II. Lens uptake of cholesteryl oleate and dioleoyl phosphatidylcholine. J Biomed Mater Res. 1997;37:207-211.
25. Shine WE, McCulley JP. Keratoconjunctivitis sicca associated with meibomian secretion polar lipid abnormality. Arch Ophthalmol. 1998;116:849-852.
26. Shine WE, McCulley JP. Association of meibum oleic acid with meibomian seborrhea. Cornea. 2000;19:72-74.
27. Sullivan BD, Evans JE, Dana MR, Sullivan DA. Impact of androgen deficiency on the lipid profiles in human meibomian gland secretions. Adv Exp Med Biol. 2002;506:449-458.
28. Shine WE, McCulley JP. Meibomianitis: polar lipid abnormalities. Cornea. 2004;23:781-783.
29. Ham BM, Jacob JT, Cole RB. MALDI-TOF MS of phosphorylated lipids in biological fluids using immobilized metal affinity chromatography and a solid ionic crystal matrix. Anal Chem. 2005;77: 4439-4447.
30. Butovich IA, Uchiyama E, Di Pascuale MA, McCulley JP. Liquid chromatography-mass spectrometric analysis of lipids present in human meibomian gland secretions. Lipids. 2007;42:765-776.
31. Butovich IA, Uchiyama E, McCulley JP. Lipids of human meibum: mass-spectrometric analysis and structural elucidation. J Lipid Res. 2007;48:2220-2235.
32. Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20: 470-475.
33. Moshides JS. Enzymic determination of the free cholesterol fraction of high-density lipoprotein in plasma with use of 2,4,6-tribromo-3-hydroxybenzoic acid. Clin Chem. 1988;34:1799-1804.
34. Jones L, Senchyna M, Glasier MA et al. Lysozyme and lipid deposition on silicone hydrogel contact lens materials. Eye Contact Lens. 2003;29:S75-S79; discussion S83-S84, S192-S194.
35. Maziarz EP, Stachowski MJ, Liu XM et al. Lipid deposition on silicone hydrogel lenses, part I: quantification of oleic acid, oleic acid methyl ester, and cholesterol. Eye Contact Lens. 2006;32: 300-307.
36. Glasson M, Stapleton F, Willcox M. Lipid, lipase and lipocalin differences between tolerant and intolerant contact lens wearers. Curr Eye Res. 2002;25:227-235.
37. Carney FP, Nash WL, Sentell KB. The adsorption of major tear film lipids in vitro to various silicone hydrogels over time. Invest Ophthalmol Vis Sci. 2008;49:120-124.
38. Iwata M, Ohno S, Kawai T, Ichijima H, Cavanagh HD. In vitro evaluation of lipids adsorbed on silicone hydrogel contact lenses using a new gas chromatography/mass spectrometry analytical method. Eye Contact Lens. 2008;34:272-280.