Meiotic recombination provokes functional activation of the p53 regulatory network

Science

Volumn 328, Issue 5983, 2010, Pages 1278-1281

  Lu, Wan Jin ^a   Chapo, Joseph ^a   Roig, Ignasi ^b   Abrams, John M ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; GREEN FLUORESCENT PROTEIN; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN;

BIOCHEMISTRY; CYTOLOGY; DISEASE CONTROL; DNA; ENZYME ACTIVITY; FLY; PHYSIOLOGY; PROTEIN; TUMOR;

ARTICLE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DROSOPHILA; GENETIC RECOMBINATION; GENOTYPE; GERM LINE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MEIOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

MUS;

EID: 77953236291     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1185640     Document Type: Article

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32. We thank S. Keeney for helpful discussions and reading of the manuscript and A. Ali, A. D'Brot, and A. Olivo for assisting experiments. We also thank the following individuals, laboratories, or facilities for helpful discussions, access to instruments, or providing reagents: S. Barolo, M. Buszczak, D. Castrillon, O. Cleaver, K. Hamra, J. Maines, D. McKearin, T. Schupbach, Y. Rong, J. Shelton, T. Wilkie, R. Bachoo, T. Mashimo, B. Thaden, Live Cell Imaging Facility (Univ. of Texas Southwestern), Bloomington Stock Center (Indiana Univ.), Developmental Studies Hybridoma Bank (Univ. of Iowa). This work was supported by the National Institute of General Medical Sciences (grant R01GM072124) and the National Institute on Alcohol Abuse and Alcoholism (grant R01AA017328).