메뉴 건너뛰기




Volumn 10, Issue 7, 2010, Pages 751-759

Comparative study of structurally related peptidoglycan monomer and muramyl dipeptide on humoral IgG immune response to ovalbumin in mouse

Author keywords

Adjuvant activity; Muramyl dipeptide; Ovalbumin; Peptidoglycan monomer

Indexed keywords

FREUND ADJUVANT; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; MURAMYL DIPEPTIDE; OVALBUMIN; PEPTIDOGLYCAN MONOMER; UNCLASSIFIED DRUG;

EID: 77953231697     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.04.005     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 0031042884 scopus 로고    scopus 로고
    • Adjuvants - a classification and review of their modes of action
    • Cox J.C., and Coulter A.R. Adjuvants - a classification and review of their modes of action. Vaccine 15 3 (1997) 248-256
    • (1997) Vaccine , vol.15 , Issue.3 , pp. 248-256
    • Cox, J.C.1    Coulter, A.R.2
  • 2
    • 0034125081 scopus 로고    scopus 로고
    • Immunological concepts of vaccine adjuvant activity
    • Schijns E.J.C.V. Immunological concepts of vaccine adjuvant activity. Curr Opin Immunol 12 (2000) 456-463
    • (2000) Curr Opin Immunol , vol.12 , pp. 456-463
    • Schijns, E.J.C.V.1
  • 3
    • 34247169514 scopus 로고    scopus 로고
    • Vaccine adjuvants revisited
    • Aguilar J.C., and Rodriguez E.G. Vaccine adjuvants revisited. Vaccine 25 (2007) 3752-3762
    • (2007) Vaccine , vol.25 , pp. 3752-3762
    • Aguilar, J.C.1    Rodriguez, E.G.2
  • 4
    • 0016200846 scopus 로고
    • Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives
    • Ellouz F., Adam A., Ciobaru R., and Lederer E. Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem Biophys Res Commun 59 (1974) 1317-1325
    • (1974) Biochem Biophys Res Commun , vol.59 , pp. 1317-1325
    • Ellouz, F.1    Adam, A.2    Ciobaru, R.3    Lederer, E.4
  • 5
    • 17044422474 scopus 로고    scopus 로고
    • Immunomodulatory activity of analog of muramyl dipeptide and their use as adjunct to chemotherapy of Leishmania donovani in hamster
    • Puri A., Sahai R., Haq W., Zaidi A., Guru P.Y., Tripathi L.M., et al. Immunomodulatory activity of analog of muramyl dipeptide and their use as adjunct to chemotherapy of Leishmania donovani in hamster. Int Immunopharmacol 5 (2005) 937-946
    • (2005) Int Immunopharmacol , vol.5 , pp. 937-946
    • Puri, A.1    Sahai, R.2    Haq, W.3    Zaidi, A.4    Guru, P.Y.5    Tripathi, L.M.6
  • 6
    • 0028815098 scopus 로고
    • Effects of muramyl dipeptide derivates as adjuvants on the induction of antibody response to recombinant hepatitis B surface antigen
    • Tamura M., Yoo Y.C., Yoshimatsu K., Yoshida R., Oka T., Ohkuma K., et al. Effects of muramyl dipeptide derivates as adjuvants on the induction of antibody response to recombinant hepatitis B surface antigen. Vaccine 13 1 (1995) 77-82
    • (1995) Vaccine , vol.13 , Issue.1 , pp. 77-82
    • Tamura, M.1    Yoo, Y.C.2    Yoshimatsu, K.3    Yoshida, R.4    Oka, T.5    Ohkuma, K.6
  • 7
    • 0026564321 scopus 로고
    • Synthetic immunoadjuvants: application to non-specific host stimulation and potentiation of vaccine immunogenicity
    • Azuma I. Synthetic immunoadjuvants: application to non-specific host stimulation and potentiation of vaccine immunogenicity. Vaccine 10 14 (1992) 1000-1006
    • (1992) Vaccine , vol.10 , Issue.14 , pp. 1000-1006
    • Azuma, I.1
  • 8
    • 0031986108 scopus 로고    scopus 로고
    • Adjuvant activity of muramyl dipeptide derivatives to enhance immunogenicity of a hantavirus-inactivated vaccine
    • Yoo Y.C., Yoshimatsu K., Koike Y., Hatsuse R., Yamanishi K., Tanishita O., et al. Adjuvant activity of muramyl dipeptide derivatives to enhance immunogenicity of a hantavirus-inactivated vaccine. Vaccine 16 (1998) 216-224
    • (1998) Vaccine , vol.16 , pp. 216-224
    • Yoo, Y.C.1    Yoshimatsu, K.2    Koike, Y.3    Hatsuse, R.4    Yamanishi, K.5    Tanishita, O.6
  • 9
    • 0030981761 scopus 로고    scopus 로고
    • Study of the adjuvant activity of new MDP derivatives and purified saponins and their influence on HIV-1 replication in vitro
    • Krivorutchenko Y.L., Andronovskaja I.B., Hinkula J., Krivoshein Y.S., Ljungdahl-Ståhle E., Pertel S.S., et al. Study of the adjuvant activity of new MDP derivatives and purified saponins and their influence on HIV-1 replication in vitro. Vaccine 15 12-13 (1997) 1479-1486
    • (1997) Vaccine , vol.15 , Issue.12-13 , pp. 1479-1486
    • Krivorutchenko, Y.L.1    Andronovskaja, I.B.2    Hinkula, J.3    Krivoshein, Y.S.4    Ljungdahl-Ståhle, E.5    Pertel, S.S.6
  • 10
    • 33646914384 scopus 로고    scopus 로고
    • MDP and other muropeptides - direct and synergistic effects on the immune system
    • Traub S., von Aulock S., Hartung T., and Hermann C. MDP and other muropeptides - direct and synergistic effects on the immune system. J Endotoxin Res 12 2 (2006) 69-85
    • (2006) J Endotoxin Res , vol.12 , Issue.2 , pp. 69-85
    • Traub, S.1    von Aulock, S.2    Hartung, T.3    Hermann, C.4
  • 11
    • 0034886905 scopus 로고    scopus 로고
    • Enhanced maturation and functional capacity of monocyte-derived immature dendritic cells by the synthetic immunomodulator Murabutide
    • Vidal V., Dewulf J., and Bahr G.M. Enhanced maturation and functional capacity of monocyte-derived immature dendritic cells by the synthetic immunomodulator Murabutide. Immunology 103 (2001) 479-487
    • (2001) Immunology , vol.103 , pp. 479-487
    • Vidal, V.1    Dewulf, J.2    Bahr, G.M.3
  • 12
    • 33747037585 scopus 로고    scopus 로고
    • Immunomodulatory properties of new conjugates of muramyl dipeptide and nor-muramyl dipeptide with retro-tuftsin (Arg-Pro-Lys-Thr-OMe)
    • Wardowska A., Dzierzbicka K., Trzonkowski P., and Mysliwski A. Immunomodulatory properties of new conjugates of muramyl dipeptide and nor-muramyl dipeptide with retro-tuftsin (Arg-Pro-Lys-Thr-OMe). Int Immunopharmacol 6 (2006) 1560-1568
    • (2006) Int Immunopharmacol , vol.6 , pp. 1560-1568
    • Wardowska, A.1    Dzierzbicka, K.2    Trzonkowski, P.3    Mysliwski, A.4
  • 13
    • 33750557881 scopus 로고    scopus 로고
    • Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling
    • Takada H., and Uehara A. Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling. Curr Pharm Design 12 (2006) 4163-4172
    • (2006) Curr Pharm Design , vol.12 , pp. 4163-4172
    • Takada, H.1    Uehara, A.2
  • 14
    • 0018359872 scopus 로고
    • Isolation procedure and properties of monomer unit from lysozyme digest of peptidoglycan complex excreted into the medium by penicillin-treated Brevibacterium divaricatum mutant
    • Keglević D., Ladešić B., Tomašić J., Valinger Z., and Naumski R. Isolation procedure and properties of monomer unit from lysozyme digest of peptidoglycan complex excreted into the medium by penicillin-treated Brevibacterium divaricatum mutant. Biochim Biophys Acta 585 (1979) 273-281
    • (1979) Biochim Biophys Acta , vol.585 , pp. 273-281
    • Keglević, D.1    Ladešić, B.2    Tomašić, J.3    Valinger, Z.4    Naumski, R.5
  • 15
    • 0024296686 scopus 로고
    • Comparative susceptibility of a peptidoglycan monomer from Brevibacterium divaricatum and its anhydromuramyl analogue to hydrolysis with N-acetylmuramyl-l-alanine amidase
    • Tomašić J., Sesartić L.J., Martin S.A., Valinger Z., and Ladešić B. Comparative susceptibility of a peptidoglycan monomer from Brevibacterium divaricatum and its anhydromuramyl analogue to hydrolysis with N-acetylmuramyl-l-alanine amidase. J Chromatogr 440 (1988) 405-414
    • (1988) J Chromatogr , vol.440 , pp. 405-414
    • Tomašić, J.1    Sesartić, L.J.2    Martin, S.A.3    Valinger, Z.4    Ladešić, B.5
  • 16
    • 0005137072 scopus 로고
    • Peptidoglycan monomer originating from Brevibacterium divaricatum - its metabolism and biological activities in the host
    • Schrinner E., Richmond M.H., Seibert G., and Schwarz U. (Eds), VCH, Weinheim
    • Tomašić J., and Hršak I. Peptidoglycan monomer originating from Brevibacterium divaricatum - its metabolism and biological activities in the host. In: Schrinner E., Richmond M.H., Seibert G., and Schwarz U. (Eds). Surface Structures of Microorganisms and Their Interactions with the Mammalian Host (1987), VCH, Weinheim 113-121
    • (1987) Surface Structures of Microorganisms and Their Interactions with the Mammalian Host , pp. 113-121
    • Tomašić, J.1    Hršak, I.2
  • 17
    • 0037803776 scopus 로고    scopus 로고
    • Comparative study of the effects of peptidoglycan monomer and structurally related adamantyltripeptides on humoral immune response to ovalbumin in the mouse
    • Tomašić J., Hanzl-Dujmović I., Špoljar B., Vranešić B., Šantak M., and Jovičić A. Comparative study of the effects of peptidoglycan monomer and structurally related adamantyltripeptides on humoral immune response to ovalbumin in the mouse. Vaccine 18 (2000) 1236-1243
    • (2000) Vaccine , vol.18 , pp. 1236-1243
    • Tomašić, J.1    Hanzl-Dujmović, I.2    Špoljar, B.3    Vranešić, B.4    Šantak, M.5    Jovičić, A.6
  • 19
    • 0037435980 scopus 로고    scopus 로고
    • Adjuvant activity of peptidoglycan monomer and its metabolic products
    • Halassy B., Krstanović M., Frkanec R., and Tomašić J. Adjuvant activity of peptidoglycan monomer and its metabolic products. Vaccine 21 (2003) 971-976
    • (2003) Vaccine , vol.21 , pp. 971-976
    • Halassy, B.1    Krstanović, M.2    Frkanec, R.3    Tomašić, J.4
  • 20
    • 0021216617 scopus 로고
    • Changes in rabbit febrile responses to muramyl dipeptide (MDP) after coupling to a synthetic carrier
    • Riveau G., Parant M., and Chedid L. Changes in rabbit febrile responses to muramyl dipeptide (MDP) after coupling to a synthetic carrier. J Leukoc Biol 36 (1984) 111-122
    • (1984) J Leukoc Biol , vol.36 , pp. 111-122
    • Riveau, G.1    Parant, M.2    Chedid, L.3
  • 22
    • 0023141528 scopus 로고
    • Bacterial peptidoglycans as modulators of sleep. I. Anhydro forms of muramyl peptides enhance somnogenic potency
    • Krueger J.M., Rosenthal R.S., Martin S.A., Walter J., Davenne D., Shoham S., et al. Bacterial peptidoglycans as modulators of sleep. I. Anhydro forms of muramyl peptides enhance somnogenic potency. Brain Res 403 (1987) 249-257
    • (1987) Brain Res , vol.403 , pp. 249-257
    • Krueger, J.M.1    Rosenthal, R.S.2    Martin, S.A.3    Walter, J.4    Davenne, D.5    Shoham, S.6
  • 23
    • 0021747018 scopus 로고
    • Peptidoglycans as promoters of slow-wave sleep. I. Structure of the sleep-promoting factor isolated from human urine
    • Martin S.A., Karnovsky M.L., Krueger J.M., Pappenheimer J.R., and Biemann K. Peptidoglycans as promoters of slow-wave sleep. I. Structure of the sleep-promoting factor isolated from human urine. J Biol Chem 259 (1984) 12652-12658
    • (1984) J Biol Chem , vol.259 , pp. 12652-12658
    • Martin, S.A.1    Karnovsky, M.L.2    Krueger, J.M.3    Pappenheimer, J.R.4    Biemann, K.5
  • 24
    • 0021679371 scopus 로고
    • Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination
    • Krueger J.M., Karnovsky M.L., Martin S.A., Pappenheimer J.R., Walter J., and Biemann K. Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination. J Biol Chem 259 (1984) 12659-12662
    • (1984) J Biol Chem , vol.259 , pp. 12659-12662
    • Krueger, J.M.1    Karnovsky, M.L.2    Martin, S.A.3    Pappenheimer, J.R.4    Walter, J.5    Biemann, K.6
  • 25
    • 0001802682 scopus 로고
    • The assessment and use of adjuvants
    • Gregoriadis G., et al. (Ed), Plenum press, New York
    • Stewart-Tull D.E.S. The assessment and use of adjuvants. In: Gregoriadis G., et al. (Ed). Vaccines (1991), Plenum press, New York 85-92
    • (1991) Vaccines , pp. 85-92
    • Stewart-Tull, D.E.S.1
  • 26
    • 0001522148 scopus 로고
    • Recommendations for the assessment of adjuvants (immunopotentiators)
    • Gregoriadis G., Allison A.C., and Poste G. (Eds), Plenum Publishing Corporation, New York
    • Stewart-Tull D.E.S. Recommendations for the assessment of adjuvants (immunopotentiators). In: Gregoriadis G., Allison A.C., and Poste G. (Eds). Immunological Adjuvants and Vaccines (1991), Plenum Publishing Corporation, New York 213-226
    • (1991) Immunological Adjuvants and Vaccines , pp. 213-226
    • Stewart-Tull, D.E.S.1
  • 27
    • 0019771196 scopus 로고
    • Muramyl peptides. Chemical structure, biological activity and mechanisms of action
    • Adam A., Petit J.F., Lefrancier P., and Lederer E. Muramyl peptides. Chemical structure, biological activity and mechanisms of action. Mol Cell Biochem 41 (1981) 27-47
    • (1981) Mol Cell Biochem , vol.41 , pp. 27-47
    • Adam, A.1    Petit, J.F.2    Lefrancier, P.3    Lederer, E.4
  • 28
    • 0037172929 scopus 로고    scopus 로고
    • Reversed-phase high-performance liquid chromatographic method for the determination of peptidoglycan monomers and structurally related peptides and adamantyltripeptides
    • Krstanović M., Frkanec R., Vranešić B., Ljevaković D{stroke}., Šporec V., and Tomašić J. Reversed-phase high-performance liquid chromatographic method for the determination of peptidoglycan monomers and structurally related peptides and adamantyltripeptides. J Chromatogr B 773 (2002) 167-174
    • (2002) J Chromatogr B , vol.773 , pp. 167-174
    • Krstanović, M.1    Frkanec, R.2    Vranešić, B.3    Ljevaković, D.4    Šporec, V.5    Tomašić, J.6
  • 29
    • 33645338707 scopus 로고    scopus 로고
    • Effect of liposomal formulations and immunostimulating peptidoglycan monomer (PGM) on the immune reaction to ovalbumin in mice
    • Habjanec L., Frkanec R., Halassy B., and Tomašić J. Effect of liposomal formulations and immunostimulating peptidoglycan monomer (PGM) on the immune reaction to ovalbumin in mice. J Liposome Res 16 (2006) 1-16
    • (2006) J Liposome Res , vol.16 , pp. 1-16
    • Habjanec, L.1    Frkanec, R.2    Halassy, B.3    Tomašić, J.4
  • 30
    • 41349084148 scopus 로고    scopus 로고
    • Immunomodulatory activity of novel adjuvant formulations based on Montanide ISA oil-based adjuvants and peptidoglycan monomer
    • Habjanec L., Halassy B., and Tomašić J. Immunomodulatory activity of novel adjuvant formulations based on Montanide ISA oil-based adjuvants and peptidoglycan monomer. Int Immunopharmacol 8 (2008) 717-724
    • (2008) Int Immunopharmacol , vol.8 , pp. 717-724
    • Habjanec, L.1    Halassy, B.2    Tomašić, J.3
  • 31
    • 0344915162 scopus 로고    scopus 로고
    • Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response
    • Yip H.C., Karulin A.Y., Tary-Lehmann M., Hesse M.D., Radeke H., Heeger P.S., et al. Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response. J Immunol 162 (1999) 3942-3949
    • (1999) J Immunol , vol.162 , pp. 3942-3949
    • Yip, H.C.1    Karulin, A.Y.2    Tary-Lehmann, M.3    Hesse, M.D.4    Radeke, H.5    Heeger, P.S.6
  • 32
    • 0037159625 scopus 로고    scopus 로고
    • CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune response to a herpesvirus glycoprotein
    • Ioannou X.P., Gomis S.M., Karvonen B., Hecker R., Babiuk L.A., and van Drunen Littel-van den Hurk S. CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune response to a herpesvirus glycoprotein. Vaccine 21 (2002) 127-137
    • (2002) Vaccine , vol.21 , pp. 127-137
    • Ioannou, X.P.1    Gomis, S.M.2    Karvonen, B.3    Hecker, R.4    Babiuk, L.A.5    van Drunen Littel-van den Hurk, S.6
  • 36
    • 32044443144 scopus 로고    scopus 로고
    • Modulating the adjuvanticity of alum by co-administration of muramyl di-peptide (MDP) or Quil-A
    • Moschos S.A., Bramwell V.W., Somavarapu S., and Alpar O. Modulating the adjuvanticity of alum by co-administration of muramyl di-peptide (MDP) or Quil-A. Vaccine 24 (2006) 1081-1086
    • (2006) Vaccine , vol.24 , pp. 1081-1086
    • Moschos, S.A.1    Bramwell, V.W.2    Somavarapu, S.3    Alpar, O.4
  • 37
    • 14244264350 scopus 로고    scopus 로고
    • Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation
    • Moschos S.A., Bramwell V.W., Somavarapu S., and Alpar O. Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation. Vaccine 23 (2005) 1923-1930
    • (2005) Vaccine , vol.23 , pp. 1923-1930
    • Moschos, S.A.1    Bramwell, V.W.2    Somavarapu, S.3    Alpar, O.4
  • 38
    • 0012722659 scopus 로고    scopus 로고
    • Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
    • Girardin S.E., Boneca I.G., Viala J., Chamaillard M., Labigne A., Thomas G., et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278 11 (2003) 8869-8872
    • (2003) J Biol Chem , vol.278 , Issue.11 , pp. 8869-8872
    • Girardin, S.E.1    Boneca, I.G.2    Viala, J.3    Chamaillard, M.4    Labigne, A.5    Thomas, G.6
  • 40
    • 7944232105 scopus 로고    scopus 로고
    • Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
    • Martinon F., Agostini L., Meylan E., and Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol 14 (2004) 1929-1934
    • (2004) Curr Biol , vol.14 , pp. 1929-1934
    • Martinon, F.1    Agostini, L.2    Meylan, E.3    Tschopp, J.4
  • 41
    • 0032191916 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger P. An innate sense of danger. Semin Immunol 10 (1998) 399-415
    • (1998) Semin Immunol , vol.10 , pp. 399-415
    • Matzinger, P.1
  • 42
    • 51849103168 scopus 로고    scopus 로고
    • The microbial and danger signals that activate Nod-like receptors
    • Benko S., Philpott D.J., and Girardin S.E. The microbial and danger signals that activate Nod-like receptors. Cytokine 43 3 (2008) 368-373
    • (2008) Cytokine , vol.43 , Issue.3 , pp. 368-373
    • Benko, S.1    Philpott, D.J.2    Girardin, S.E.3
  • 43
    • 0030049937 scopus 로고    scopus 로고
    • Structural characteristics of peptidoglycan fragments required to prime mice for induction of anaphylactoid reactions to lipopolysaccharides
    • Takada H., Kawabata Y., Kawata S., and Kusumoto S. Structural characteristics of peptidoglycan fragments required to prime mice for induction of anaphylactoid reactions to lipopolysaccharides. Infect Immun 64 (1996) 657-659
    • (1996) Infect Immun , vol.64 , pp. 657-659
    • Takada, H.1    Kawabata, Y.2    Kawata, S.3    Kusumoto, S.4
  • 44
    • 0023190098 scopus 로고
    • Structural requirements of muramylpeptides for induction of necrosis at sites primed with Mycobacterium tuberculosis in guinea pigs
    • Nagao S., Takada H., Yagawa K., Kutsukake H., Shiba T., Kusumoto S., et al. Structural requirements of muramylpeptides for induction of necrosis at sites primed with Mycobacterium tuberculosis in guinea pigs. Infect Immun 55 (1987) 1279-1288
    • (1987) Infect Immun , vol.55 , pp. 1279-1288
    • Nagao, S.1    Takada, H.2    Yagawa, K.3    Kutsukake, H.4    Shiba, T.5    Kusumoto, S.6
  • 45
    • 23644455974 scopus 로고    scopus 로고
    • Revisiting Freund's incomplete adjuvant for vaccines in the developing world
    • Miller L.H., Saul A., and Mahanty S. Revisiting Freund's incomplete adjuvant for vaccines in the developing world. Trends Parasitol 21 9 (2005) 412-414
    • (2005) Trends Parasitol , vol.21 , Issue.9 , pp. 412-414
    • Miller, L.H.1    Saul, A.2    Mahanty, S.3
  • 46
    • 53449085985 scopus 로고    scopus 로고
    • Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2
    • Moreira L.O., Smith A.M., DeFreitas A.A., Qualls J.E., El Kasmi K.C., and Murray P.J. Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2. Vaccine 26 (2008) 5808-5813
    • (2008) Vaccine , vol.26 , pp. 5808-5813
    • Moreira, L.O.1    Smith, A.M.2    DeFreitas, A.A.3    Qualls, J.E.4    El Kasmi, K.C.5    Murray, P.J.6
  • 48
    • 38749096634 scopus 로고    scopus 로고
    • Comparison of mouse and rabbit model for the assessment of strong PGM-containing oil-based adjuvants
    • Habjanec L., Halassy B., Vdović V., Lang Balija M., and Tomašić J. Comparison of mouse and rabbit model for the assessment of strong PGM-containing oil-based adjuvants. Vet Immunol Immunopathol 121 (2008) 232-240
    • (2008) Vet Immunol Immunopathol , vol.121 , pp. 232-240
    • Habjanec, L.1    Halassy, B.2    Vdović, V.3    Lang Balija, M.4    Tomašić, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.