Factor Seven Activating Protease (FSAP) levels during normal pregnancy and in women using oral contraceptives

Thrombosis Research

Volumn 126, Issue 1, 2010, Pages

  Parahuleva, Mariana S ^a   Hölschermann, Hans ^c   Erdogan, Ali ^a   Langanke, Eva ^a   Prickartz, Isabella ^a   Parviz, Behnoush ^a   Weiskirchen, Ralf ^b   Tillmanns, Harald ^a   Kanse, Sandip M ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c Krankenhaus Bad Homburg   (Germany)

Author keywords

Estrogen; Fibrinolysis; Monocytes; Remodelling; Thrombosis

Indexed keywords

DESOGESTREL; ESTRADIOL; FACTOR SEVEN ACTIVATING PROTEASE; FULVESTRANT; LEVONORGESTREL; MESSENGER RNA; MIFEPRISTONE; PROGESTERONE; SERINE PROTEINASE; UNCLASSIFIED DRUG; ORAL CONTRACEPTIVE AGENT;

ADULT; ANTIGEN EXPRESSION; ANTIGENICITY; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CELL CULTURE; CELL ISOLATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIVERY; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; MONOCYTE; MONONUCLEAR CELL; NORMAL HUMAN; ORAL CONTRACEPTION; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUERPERIUM; TREATMENT DURATION; ADOLESCENT; BLOOD CLOTTING; CONTRACEPTION; DRUG EFFECT; HEMOSTASIS;

ADOLESCENT; ADULT; BLOOD COAGULATION; CONTRACEPTION; CONTRACEPTIVES, ORAL; ESTRADIOL; FEMALE; HEMOSTASIS; HUMANS; PREGNANCY; PROSPECTIVE STUDIES; SERINE PROTEASES; YOUNG ADULT;

EID: 77953231343     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.03.003     Document Type: Article

References (25)

1. Holmes V.A., and Wallace J.M. Haemostasis in normal pregnancy: a balancing act?. Biochem Soc Trans 33 (2005) 428-432
2. O'Riordan M.N., and Higgins J.R. Haemostasis in normal and abnormal pregnancy. Best Pract Res Clin Obstet Gynaecol 17 (2003) 385-396
3. Sandset P.M., Hoibraaten E., Eilertsen A.L., and Dahm A. Mechanisms of thrombosis related to hormone therapy. Thromb Res 123 (2009) S70-S73
4. Davis P.H. Use of oral ontraceptives and postmenopausal hormone replacement: evidence on risk of stroke. Curr Treat Options Neurol 10 (2008) 468-474
5. Brenner B. Haemostatic changes in pregnancy. Thromb Res 114 (2004) 409-414
6. Marchi R., López Ramirez Y., Nagaswami C., Masova L., Pulido A., López Mora J., et al. Haemostatic changes related to fibrin formation and fibrinolysis during the first trimester in normal pregnancy and in recurrent miscarriage. Thromb Haemost 97 (2007) 552-557
7. Römisch J., Feussner A., Vermöhlen S., and Stöhr H.A. A protease isolated from human plasma activating Factor VII independent of tissue factor. Blood Coagul Fibrinolysis 10 (1999) 471-479
8. Römisch J., Vermöhlen S., Feussner A., and Stöhr H.A. The FVII Activating Protease Cleaves Single-Chain Plasminogen Activators. Haemostasis 29 (1999) 292-299
9. Roemisch J., Feussner A., Nerlich C., Stoehr H.A., and Weimer T. The frequent Marburg I polymorphism impairs the pro-urokinase activating potency of the factor VII activating protease (FSAP). Blood Coagul Fibrinolysis 13 (2002) 433-441
10. Parahuleva M.S., Kanse S.M., Parviz B., Barth A., Tillmanns H., Bohle R.M., et al. Factor Seven Activating Protease (FSAP) expression in human monocytes and accumulation in unstable coronary atherosclerotic plaques. Atherosclerosis 196 (2008) 164-171
11. Willeit J., Kiechl S., Weimer T., Mair A., Santer P., Wiedermann C.J., et al. polymorphism of factor VII.activating protease: a prominent risk predictor of carotid stenosis. Circulation 107 (2003) 667-670
12. Hoppe B., Tolou F., Radtke H., Kiesewtter H., Dörner T., and Salama A. Marburg I polymorphism of factor VII-activating protease is associated with idiopathic venous thromboembolism. Blood 105 (2005) 1549-1551
13. Sidelmann J.J., Vitzthum F., Funding E., Münster A.M., Gram J., and Jespersen J. Factor VII-activating protease in patients with acute deep venous thrombosis. Thromb Res 122 (2008) 848-853
14. Ireland H., Miller G.J., Webb K.E., Cooper J.A., and Humphries S.E. The factor VII-activating protease G511E (Marburg) variant and cardiovascular risk. Thromb Haemost 92 (2004) 986-992
15. Reiner A.P., Lange L.A., Smith N.L., Zakai N.A., Cushman M., and Folsom A.R. Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study. J Thromb Haemost 7 (2009) 1499-1505
16. Stephan S., Schwarz H., Borchert A., Bussfeld D., Quak E., Simshaeuser-Knaub B., et al. Tests for the measurement of factor VII-activating protease (FSAP) activity and antigen levels in citrated plasma, their correlation to PCR testing, and utility for the detection of the Marburg I-polymorphism of FSAP. Clin Chem Lab Med 46 (2008) 1109-1116
17. Tag C.G., Mengsteab S., Weiskirchen R., and Kanse S.M. Rapid genotyping of the G534E polymorphism (Marburg I) of the gene encoding the factor VII-activating protease (FSAP) by LightCycler PCR. Clin Biochem 40 (2007) 1063-1064
18. Gressner O.A., Lahme B., Demirci I., Gressner A.M., and Weiskirchen R. Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes. J Hepatol 47 (2007) 699-710
19. Hölschermann H., Dürfeld F., Maus U., Bierhaus A., Heidinger K., Lohmeyer J., et al. Cyclosporine a inhibits tissue factor expression in monocytes/macrophages. Blood 88 (1996) 3837-3845
20. Hölschermann H., Terhalle H.M., Zakel U., Maus U., Parviz B., Tillmanns H., et al. Monocyte tissue factor expression is enhanced in women who smoke and use oral contraceptives. Thromb Haemost 82 (1999) 1614-1620
21. Franchini M. Haemostasis and pregnancy. Thromb Haemost 95 (2006) 401-413
22. Sattar N., Greer I.A., Rumley A., Stewart G., Shepherd J., Packard C.J., et al. A longitudinal study of the relationships between haemostatic, lipid, and oestradiol changes during normal human pregnancy. Thromb Haemost 81 (1999) 71-75
23. Sidelmann J.J., Skouby S.O., Kluft C., Winkler U., Vitzthum F., Schwarz H., et al. The effect of monophasic oral contraceptive regimens on factor VII-activating protease - a randomised multicentre study. J Thromb Haemost 7 (2009) 137
24. Roemisch J., Feussner A., and Stoehr H.A. Quantitation of the factor VII- and single-chain plasminogen activator-activating protease in plasmas of healthy subjects. Blood Coagul Fibrinolysis 12 (2001) 375-383
25. Meyer M.R., and Barton M. ERalpha, ERbeta, and gpER: novel aspects of oestrogen receptor signalling in atherosclerosis. Cardiovasc Res 83 (2009) 605-610