New Insights into cytokine gene expression in the rat hypothalamus following endotoxin challenge

Neurochemical Research

Volumn 35, Issue 6, 2010, Pages 909-911

  Jessop, David S ^a   Besedovsky, Hugo O ^b   Del Rey, Adriana ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Arthritis; Cytokines; Endotoxin; Hypothalamus; Inflammation; Spleen; Stress

Indexed keywords

CORTICOSTERONE; ENDOTOXIN; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADJUVANT ARTHRITIS; ADRENERGIC SYSTEM; ANTIINFLAMMATORY ACTIVITY; BRAIN REGION; CONFERENCE PAPER; CORTICOSTERONE BLOOD LEVEL; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SPLEEN;

ANIMALS; CYTOKINES; GENE EXPRESSION; HYPOTHALAMUS; LIPOPOLYSACCHARIDES; ORGAN SPECIFICITY; RATS; SPLEEN;

BACTERIA (MICROORGANISMS); RATTUS;

EID: 77953229671     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-0071-0     Document Type: Conference Paper

References (33)

1. MS Harbuz 2002 Neuroendocrinology of autoimmunity Int Rev Neurobiol 52 133 161 10.1016/S0074-7742(02)52008-0 1:CAS:528:DC%2BD3sXhtVyhtrw%3D 12498103
2. YH Zhang J Lu JK Elmquist, et al. 2000 Lipopolysaccharide activates specific populations of hypothalamic and brainstem neurons that project to the spinal cord J Neurosci 20 6578 6586 1:CAS:528:DC%2BD3cXmsVygsrg%3D 10964963
3. HO Besedovsky A del Rey 1996 Immune-neuro-endocrine interactions: facts and hypotheses Endocr Rev 17 64 102 1:CAS:528:DyaK28XhslymtL4%3D 8641224
4. VM Sanders AP Kohm 2002 Sympathetic nervous system interaction with the immune system Int Rev Neurobiol 52 17 41 10.1016/S0074-7742(02)52004-3 1:CAS:528:DC%2BD3sXhtVyhsbo%3D 12498099
5. JI Webster L Tonelli EM Sternberg 2002 Neuroendocrine regulation of immunity Annu Rev Immunol 20 125 163 10.1146/annurev.immunol.20.082401.104914 1:CAS:528:DC%2BD38XjtlWgt7g%3D 11861600 (Pubitemid 34295785)
6. CD Breder C Hazuka T Ghayur, et al. 1994 Regional induction of tumor necrosis factor alpha expression in the mouse brain after systemic lipopolysaccharide administration Proc Natl Acad Sci USA 91 11393 11397 10.1073/pnas.91.24.11393 1:CAS:528:DyaK2MXitlyrs74%3D 7972071 (Pubitemid 24356350)
7. S Laye P Parnet E Goujon 1994 Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice Brain Res Mol Brain Res 27 157 162 10.1016/0169-328X(94) 90197-X 1:CAS:528:DyaK2cXmslyksrk%3D 7877446 (Pubitemid 24324102)
8. F Pitossi A del Rey A Kabiersch 1997 Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice J Neurosci Res 48 287 298 10.1002/(SICI)1097-4547(19970515) 48:4<287:AID-JNR1>3.0.CO;2-7 1:CAS:528:DyaK2sXjs1Cqsb8%3D 9169855
9. ML Wong PB Bongiorno V Rettori, et al. 1997 Interleukin (IL) 1beta, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implications Proc Natl Acad Sci USA 94 227 232 10.1073/pnas.94.1.227 1:CAS:528:DyaK2sXktVClsw%3D%3D 8990190 (Pubitemid 27027191)
10. N Quan M Whiteside M Herkenham 1998 Time course and localization patterns of interleukin-1beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide Neuroscience 83 281 293 10.1016/S0306-4522(97)00350-3 1:CAS:528:DyaK1cXitVOlug%3D%3D 9466417 (Pubitemid 28068057)
11. N Castanon C Medina C Mormede, et al. 2004 Chronic administration of tianeptine balances lipopolysaccharide-induced expression of cytokines in the spleen and hypothalamus of rats Psychoneuroendocrinology 29 778 790 10.1016/S0306-4530(03)00142-2 1:CAS:528:DC%2BD2cXjsVWntbs%3D 15110927 (Pubitemid 38521240)
12. R Chen H Zhou J Beltran, et al. 2005 Differential expression of cytokines in the brain and serum during endotoxin tolerance J Neuroimmunol 163 53 72 10.1016/j.jneuroim.2005.02.012 1:CAS:528:DC%2BD2MXktVGlu70%3D 15885308 (Pubitemid 40692949)
13. M Roche M Diamond JP Kelly, et al. 2006 In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids J Neuroimmunol 181 57 67 10.1016/j.jneuroim.2006.08.001 1:CAS:528:DC%2BD28Xht1Krs7bE 17011047 (Pubitemid 44827290)
14. MS Harbuz LJ Richards AJ Chover-Gonzalez, et al. 2006 Stress in autoimmune disease models Ann N Y Acad Sci 1069 51 61 10.1196/annals.1351.005 1:CAS:528:DC%2BD28XovF2gsrY%3D 16855134 (Pubitemid 43989850)
15. LJ Richards A Chover-Gonzalez MS Harbuz, et al. 2006 Protective effects of endotoxin in a rat model of chronic inflammation are accompanied by suppressed secretion of pro-inflammatory cytokines and biphasic alteration in hypothalamo-pituitary-adrenal axis activity J Neuroendocrinol 18 875 882 10.1111/j.1365-2826.2006.01486.x 1:CAS:528:DC%2BD28XhtF2qsL%2FF 17026537 (Pubitemid 44501991)
16. A del Rey H Furukawa G Monge-Arditi, et al. 1996 Alterations in the pituitary-adrenal axis of adult mice following neonatal exposure to interleukin-1 Brain Behav Immun 10 235 248 10.1006/brbi.1996.0021 1:CAS:528:DyaK2sXisFKnsQ%3D%3D 8954596 (Pubitemid 27007851)
17. N Shanks RJ Windle P Perks 2000 Early life exposure to endotoxin alters hypothalamic-pituitary-adrenal function and predisposition to inflammation Proc Natl Acad Sci USA 97 5645 5650 10.1073/pnas.090571897 1:CAS:528: DC%2BD3cXjsVWmsbg%3D 10779563 (Pubitemid 30313772)
18. I Huitinga ED Schmidt MJ van der Cammen 2000 Priming with interleukin-1beta suppresses experimental allergic encephalomyelitis in the Lewis rat Neuroendocrinology 12 1186 1193 10.1046/j.1365-2826.2000.00574.x 1:CAS:528:DC%2BD3cXos1ejurY%3D
19. DS Jessop LJ Richards MS Harbuz 2004 Effects of stress on inflammatory autoimmune disease: destructive or protective? Stress 7 261 266 10.1080/10253890400025497 1:CAS:528:DC%2BD2MXjvFWqur0%3D 16019592 (Pubitemid 40591427)
20. A del Rey A Randolf J Wildmann, et al. 2009 Re-exposure to endotoxin induces differential cytokine gene expression in the rat hypothalamus and spleen Brain Behav Immun 23 776 783 10.1016/j.bbi.2009.02.009 1:CAS:528: DC%2BD1MXosVGhtLY%3D 19254758
21. Besedovsky HO, del Rey A (2008) Brain cytokines as integrators of the immune-neuroendocrine network. In: Lajtha A (ed) Handbook of neurochemistry and molecular neurobiology. Springer, New York, NY, pp 1-17
22. A del Rey C Wolff J Wildmann, et al. 2008 Disrupted brain-immune system-joint communication during experimental arthritis Arthritis Rheum 58 3090 3099 10.1002/art.23869 1:CAS:528:DC%2BD1cXht12rurzI 18821705
23. J Roth JL McClellan MJ Kluger, et al. 1994 Attenuation of fever and release of cytokines after repeated injections of lipopolysaccharide in guinea-pigs J Physiol 477 177 185 1:CAS:528:DyaK2cXksFGmu7k%3D 8071885
24. R Faggioni G Fantuzzi P Villa, et al. 1995 Independent down-regulation of central and peripheral tumor necrosis factor production as a result of lipopolysaccharide tolerance in mice Infect Immun 63 1473 1477 1:CAS:528:DyaK2MXks1OntLo%3D 7890412
25. R Hadid E Spinedi T Daneva, et al. 1995 Repeated endotoxin treatment decreases immune and hypothalamo-pituitary-adrenal axis responses: effects of orchidectomy and testosterone therapy Neuroendocrinology 62 348 355 10.1159/000127024 1:CAS:528:DyaK2MXovVWjuro%3D 8544948
26. R Hadid E Spinedi A Giovambattista, et al. 1996 Decreased hypothalamo-pituitary-adrenal axis response to neuroendocrine challenge under repeated endotoxemia Neuroimmunomodulation 3 62 68 10.1159/000097228 1:CAS:528:DyaK28XmtFWnt70%3D 8892362
27. T Takemura S Makino T Takao 1997 Hypothalamic-pituitary-adrenocortical responses to single vs. repeated endotoxin lipopolysaccharide administration in the rat Brain Res 767 181 191 10.1016/S0006-8993(97)00460-5 1:CAS:528: DyaK2sXltl2lt7w%3D 9367246 (Pubitemid 27435761)
28. V Grinevich XM Ma JP Herman, et al. 2001 Effect of repeated lipopolysaccharide administration on tissue cytokine expression and hypothalamic-pituitary-adrenal axis activity in rats J Neuroendocrinol 13 711 723 10.1046/j.1365-2826.2001.00684.x 1:CAS:528:DC%2BD3MXlvFWjt7g%3D 11489088 (Pubitemid 32725579)
29. A Beishuizen LG Thijs 2003 Endotoxin and the hypothalamo-pituitary- adrenal (HPA) axis J Endotoxin Res 9 3 24 1:CAS:528:DC%2BD3sXjtVOjurk%3D 12691614
30. M Buttini H Boddeke 1995 Peripheral lipopolysaccharide stimulation induces interleukin-1 messenger RNA in rat brain microglial cells Neuroscience 65 523 530 10.1016/0306-4522(94)00525-A 1:CAS:528:DyaK2MXkt1ymtb0%3D 7777165
31. CP Chen NI Boyadjieva JP Advis, et al. 2006 Ethanol suppression of the hypothalamic proopiomelanocortin level and the splenic NK cell cytolytic activity is associated with a reduction in the expression of proinflammatory cytokines but not anti-inflammatory cytokines in neuroendocrine and immune cells Alcohol Clin Exp Res 30 1925 1932 10.1111/j.1530-0277.2006.00237.x 1:CAS:528:DC%2BD28Xht1OjtrjJ 17067358 (Pubitemid 44630096)
32. HO Besedovsky A del Rey 2007 Physiology of psychoneuroimmunology: a personal view Brain Behav Immun 21 34 44 10.1016/j.bbi.2006.09.008 1:CAS:528:DC%2BD28XhtlShsrfK 17157762 (Pubitemid 44854450)
33. D Gosselin S Rivest 2007 Role of IL-1 and TNF in the brain: twenty years of progress on a Dr. Jekyll/Mr. Hyde duality of the innate immune system Brain Behav Immun 21 281 289 10.1016/j.bbi.2006.12.004 1:CAS:528:DC%2BD2sXhs1Smt7c%3D 17275255 (Pubitemid 46199120)