The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis

Journal of Dermatological Treatment

Volumn 21, Issue 4, 2010, Pages 245-251

  Kleinpenning, Marloes M ^a   Kanis, Josine H ^a   Smits, Tim ^a   Van Erp, Piet E J ^a   Van De Kerkhof, Peter ^a   Gerritsen, Rianne M J P ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Aminolevulinic; Fluorescence diagnosis; Keratolysis; Photodynamic therapy; Psoriasis; Stratum corneum

Indexed keywords

AMINOLEVULINIC ACID; DUODERM; KERATOLYTIC AGENT; PETROLATUM; PORPHYRIN; PROTOPORPHYRIN; RETINOIC ACID; SALICYLIC ACID;

ADULT; AGED; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANALYSIS; HUMAN; HYDROCOLLOID DRESSING; HYPERKERATOSIS; MALE; OUTCOME ASSESSMENT; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PSORIASIS VULGARIS; SKIN BIOPSY; SKIN INFLAMMATION; SKIN IRRITATION; STRATUM CORNEUM; THICKNESS; TREATMENT OUTCOME; ANALYSIS OF VARIANCE; COMPARATIVE STUDY; DIAGNOSTIC USE; DRUG EFFECTS; FLUORESCENCE; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; NEEDLE BIOPSY; PATHOLOGY; PHOTOCHEMOTHERAPY; PILOT STUDY; PROBABILITY; PROCEDURES; PSORIASIS; SKIN ABSORPTION; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; AGED; AMINOLEVULINIC ACID; ANALYSIS OF VARIANCE; BANDAGES, HYDROCOLLOID; BIOPSY, NEEDLE; FEMALE; FLUORESCENCE; HUMANS; IMMUNOHISTOCHEMISTRY; KERATOLYTIC AGENTS; MALE; MIDDLE AGED; PHOTOCHEMOTHERAPY; PILOT PROJECTS; PROBABILITY; PROTOPORPHYRINS; PSORIASIS; SKIN ABSORPTION; TREATMENT OUTCOME; TRETINOIN;

EID: 77953206693     PISSN: 09546634     EISSN: 14711753     Source Type: Journal    
DOI: 10.3109/09546630903271548     Document Type: Article

References (22)

1. Fritsch C, Neumann NJ, Ruzicka T, et al. [Photodiagnostic tests. 3: Fluorescence diagnosis with delta-aminolevulinic acid-induced porphyrins (FDAP) in dermatology.] Hautarzt. 2000;51:528-543.
2. Fritsch C, Lang K, Neuse W, et al. Photodynamic diagnosis and therapy in dermatology. Skin Pharmacol Appl Skin Physiol. 1998;11:358-373.
3. Boehncke WH, Konig K, Kaufmann R, et al. Photodynamic therapy in psoriasis: Suppression of cytokine production in vitro and recording of fluorescence modification during treatment in vivo. Arch Dermatol Res. 1994;286:300-303.
4. Collins P, Robinson DJ, Stringer MR, et al. The variable response of plaque psoriasis after a single treatment with topical 5-aminolaevulinic acid photodynamic therapy. Br J Dermatol. 1997;137:743-749.
5. Radakovic-Fijan S, Blecha-Thalhammer U, Schleyer V, et al. Topical aminolaevulinic acid-based photodynamic therapy as a treatment option for psoriasis? Results of a randomized, observer-blinded study. Br J Dermatol. 2005;152:279-283.
6. Robinson DJ, Collins P, Stringer MR, et al. Improved response of plaque psoriasis after multiple treatments with topical 5-aminolaevulinic acid photodynamic therapy. Acta Derm Venereol. 1999;79:451-455.
7. Fransson J, Ros AM. Clinical and immunohistochemical evaluation of psoriatic plaques treated with topical 5-aminolaevulinic acid photodynamic therapy. Photodermatol Photoimmunol Photomed. 2005;21:326-332.
8. Stringer MR, Collins P, Robinson DJ, et al. The accumulation of protoporphyrin IX in plaque psoriasis after topical application of 5-aminolevulinic acid indicates a potential for superficial photodynamic therapy. J Invest Dermatol. 1996; 107:76-81.
9. Smits T, Kleinpenning MM, van Erp PE, et al. A placebocontrolled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acidphotodynamic therapy in patients with psoriasis. Br J Dermatol. 2006;155:429-436.
10. Fritsch C, Lehmann P, Stahl W, et al. Optimum porphyrin accumulation in epithelial skin tumours and psoriatic lesions after topical application of delta-aminolaevulinic acid. Br J Cancer. 1999;79:1603-1608.
11. Fritsch C, Ruzicka T. Fluorescence diagnosis and photodynamic therapy of skin diseases. Wien: Springer; 2003.
12. Kleinpenning MM, Smits T, Ewalds E, et al. Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: An immunohistochemical study. Br J Dermatol. 2006; 155:539-545.
13. Gerritsen MJ, Rulo HF, Van Vlijmen-Willems I, et al. Topical treatment of psoriatic plaques with 1,25-dihydroxyvitamin D3: A cell biological study. Br J Dermatol. 1993;128:666-673.
14. Presland RB, Coulombe PA, Eckert RL, et al. Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. J Invest Dermatol. 2004; 123:603-606.
15. Takaishi M, Makino T, Morohashi M, et al. Identification of human hornerin and its expression in regenerating and psoriatic skin. J Biol Chem. 2005;280:4696-4703.
16. Gerritsen MJ, Boezeman JB, van Vlijmen-Willems IM, et al. The effect of tacalcitol (1,24(OH)2D3) on cutaneous inflammation, epidermal proliferation and keratinization in psoriasis: A placebo-controlled, double-blind study. Br J Dermatol. 1994;131:57-63.
17. Gerritsen MJ, Elbers ME, de Jong EM, et al. Recruitment of cycling epidermal cells and expression of filaggrin, involucrin and tenascin in the margin of the active psoriatic plaque, in the uninvolved skin of psoriatic patients and in the normal healthy skin. J Dermatol Sci. 1997;14: 179-188.
18. Friedman SJ. Management of psoriasis vulgaris with a hydrocolloid occlusive dressing. Arch Dermatol. 1987; 123:1046-1052.
19. Gottlieb AB, Staiano-Coico L, Cohen SR, et al. Occlusive hydrocolloid dressings decrease keratinocyte population growth fraction and clinical scale and skin thickness in active psoriatic plaques. J Dermatol Sci. 1990;1:93-96.
20. Gerritsen MJ, van Vlijmen-Willems IM, Chang A, et al. The effect of a hydrocolloid occlusive dressing (DuoDERM E) on keratinization in psoriasis vulgaris. Acta Derm Venereol. 1994;74:483-484.
21. Boehncke WH, Sterry W, Kaufmann R. Treatment of psoriasis by topical photodynamic therapy with polychromatic light. Lancet. 1994;343:801.
22. Boehncke WH, Elshorst-Schmidt T, Kaufmann R. Systemic photodynamic therapy is a safe and effective treatment for psoriasis. Arch Dermatol. 2000;136:271-272.