The progress of early phase bone healing using porous granules produced from calcium phosphate cement

European Journal of Medical Research

Volumn 15, Issue 5, 2010, Pages 196-203

  Jungbluth, P ^a   Hakimi, Mohssen ^a   Grassmann, J P ^a   Schneppendahl, J ^a   Kessner, A ^a   Sager, M ^a   Hakimi, A R ^a   Becker, J ^a   Windolf, J ^a   Wild, M ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Animal model; Bone defect; Bone healing; Calcium phosphate cement; Calcium phosphate granules; Mini pig

Indexed keywords

BONE CEMENT; CALCIUM PHOSPHATE; CALCIUM PHOSPHATE GRANULE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGRAFT; BIODEGRADATION; BONE DEFECT; BONE GRAFT; BONE RADIOGRAPHY; BONE REGENERATION; BONE TRANSPLANTATION; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; DISEASE MODEL; FEMALE; HISTOPATHOLOGY; INTERMETHOD COMPARISON; METAPHYSIS; MINIPIG; MORPHOMETRICS; NONHUMAN; OSSIFICATION; POROSITY; POWDER; QUANTITATIVE ANALYSIS; WEIGHT BEARING; ANIMAL CELL; BONE MINERALIZATION; BONE REMODELING; COMPARATIVE STUDY; EARLY PHASE BONE HEALING; FRACTURE HEALING; GIANT CELL; HISTOLOGY; IN VIVO STUDY; MACROPHAGE; OSTEOLYSIS;

EID: 77953191347     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: 10.1186/2047-783x-15-5-196     Document Type: Article

References (41)

1. Walsh Wr, Vizesi F, Michael D, Auld J, Langdown A, Oliver R, Yu Y, Irie HandBruce W. Beta-TCP bone graft substitutes in a bilateral rabbit tibial defect model. Biomaterials. 2008;29: 266-271
2. Perry Cr. Bone repair techniques, bone graft, and bone graft substitutes. Clin Orthop Relat Res. 1999: 71-86.
3. Fellah Bh, Gauthier O, Weiss P, Chappard DandLayrolle P. Osteogenicity of biphasic calcium phosphate ceramics and bone autograft in a goat model. Biomaterials. 2008; 29: 1177-1188
4. Cedidi Cc, Felmerer GandBerger A. Management of defects in the groin, thigh, and pelvic region with modified contralateral TRAM/VRAM flaps. Eur J Med Res. 2005; 10: 515-520
5. Arrington Ed, Smith Wj, Chambers Hg, Bucknell Aland-Davino Na. Complications of iliac crest bone graft harvesting. Clin Orthop Relat Res. 1996: 300-309 (Pubitemid 26274684)
6. Kasten P, Vogel J, Geiger F, Niemeyer P, Luginbuhl RandSzalay K. The effect of platelet-rich plasma on healing in critical-size long-bone defects. Biomaterials. 2008;29: 3983-3992
7. Cornell Cn. Osteoconductive materials and their role as substitutes for autogenous bone grafts. Orthop Clin North Am. 1999;30:591-598
8. Petite H, Viateau V, Bensaid W, Meunier A, De Pollak C, Bourguignon M, Oudina K, Sedel LandGuillemin G. Tissue-engineered bone regeneration. Nat Biotechnol. 2000;18: 959-963
9. Okafuji N, Shimizu T, Watanabe T, Kimura A, Kurihara S, Arai Y, Furusawa K, Hasegawa HandKawakami T. Three-dimensional observation of reconstruction course of rabbit experimental mandibular defect with rhBMP-2 and atelocollagen gel. Eur J Med Res. 2006;11: 351-54.
10. Legeros Rz. Properties of osteoconductive biomaterials: calcium phosphates. Clin Orthop Relat Res. 2002: 81-98.
11. Schieker M, Heiss CandMutschler W. [Bone substitutes]. Unfallchirurg. 2008;111: 613-19; quiz 620.
12. Tas Ac. Preparation of porous apatite granules from calcium phosphate cement. J Mater Sci Mater Med. 2008;19:2231-2239
13. Burger ElandPatel V. Calcium phosphates as bone graft extenders. Orthopedics. 2007;30: 939-942
14. Bohner M, Gbureck UandBarralet Je. Technological issues for the development of more efficient calcium phosphate bone cements: a critical assessment. Biomaterials. 2005;26: 6423-6429
15. Bohner M. Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements. Injury. 2000;31 Suppl 4: 37-47.
16. Bohner M, Van Lenthe Gh, Grunenfelder S, Hirsiger W, Evison RandMuller R. Synthesis and characterization of porous beta-tricalcium phosphate blocks. Biomaterials. 2005;26: 6099-6105
17. Chow Lc. Next generation calcium phosphate-based biomaterials. Dent Mater J. 2009;28: 1-10.
18. Hillmeier J, Grafe I, Da Fonseca K, Meeder Pj, Noldge G, Libicher M, Kock Hj, Haag MandKasperk C. [The evaluation of balloonkyphoplasty for osteoporotic vertebral fractures. An interdisciplinary concept]. Orthopade. 2004;33: 893-904.
19. Kasten P, Luginbuhl R, Vogel J, Niemeyer P, Weiss S, Van Griensven M, Krettek C, Bohner M, Bosch Uand-Tonak M. [Induction of bone tissue on different matrices: an in vitro and a in vivo pilot study in the SCID mouse]. Z Orthop Ihre Grenzgeb. 2004;142: 467-475
20. Steffen T, Stoll T, Arvinte TandSchenk Rk. Porous tricalcium phosphate and transforming growth factor used for anterior spine surgery. Eur Spine J. 2001;10 Suppl 2: S132-40.
21. Wheeler Dl, Cross Ar, Eschbach Ej, Rose At, Gallogly Pm, Lewis DdandVander Griend Ra. Grafting of massive tibial subchondral bone defects in a caprine model using beta-tricalcium phosphate versus autograft. J Orthop Trauma. 2005;19: 85-91.
22. Sarkar Mr, Augat P, Shefelbine Sj, Schorlemmer S, Huber-Lang M, Claes L, Kinzl LandIgnatius A. Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials. 2006;27: 1817-1823
23. Donath K. The diagnostic value of the new method for the study of undecalcified bones and teeth with attached soft tissue (Sage-Schliff (sawing and grinding) technique). Pathol Res Pract. 1985;179: 631-633 (Pubitemid 15056362)
24. Schwarz F, Herten M, Ferrari D, Wieland M, Schmitz L, Engelhardt EandBecker J. Guided bone regeneration at dehiscence-type defects using biphasic hydroxyapatite + beta tricalcium phosphate (Bone Ceramic) or a collagen-coated natural bone mineral (BioOss Collagen): an immunohistochemical study in dogs. Int J Oral Maxillofac Surg. 2007;36: 1198-1206.
25. Lange Ta, Zerwekh Je, Peek Rd, Mooney VandHarrison Bh. Granular tricalcium phosphate in large cancellous defects. Ann Clin Lab Sci. 1986;16: 467-472
26. Jensen Ss, Bornstein Mm, Dard M, Bosshardt Ddand-Buser D. Comparative study of biphasic calcium phosphates with different HA/TCP ratios in mandibular bone defects. A long-term histomorphometric study in minipigs. J Biomed Mater Res B Appl Biomater. 2009;90: 171-81.
27. Wiltfang J, Merten Ha, Schlegel Ka, Schultze-Mosgau S, Kloss Fr, Rupprecht SandKessler P. Degradation characteristics of alpha and beta tri-calcium-phosphate (TCP) in minipigs. J Biomed Mater Res. 2002;63: 115-121
28. Schlegel Ka, Kloss Fr, Schultze-Mosgau S, Neukam FwandWiltfang J. [Osseous defect regeneration using autogenous bone alone or combined with Biogran or Algipore with and without added thrombocytes. A microradiologic evaluation]. Mund Kiefer Gesichtschir. 2003;7: 112-118
29. Ooms Em, Wolke Jg, Van De Heuvel Mt, Jeschke Band-Jansen Ja. Histological evaluation of the bone response to calcium phosphate cement implanted in cortical bone. Biomaterials. 2003;24: 989-1000.
30. Bohner MandBaumgart F. Theoretical model to determine the effects of geometrical factors on the resorption of calcium phosphate bone substitutes. Biomaterials. 2004;25: 3569-3582
31. Lu Jx, Flautre B, Anselme K, Hardouin P, Gallur A, Descamps MandThierry B. Role of interconnections in porous bioceramics on bone recolonization in vitro and in vivo. J Mater Sci Mater Med. 1999;10: 111-120
32. Habibovic P, Yuan H, Van Der Valk Cm, Meijer G, Van Blitterswijk CaandDe Groot K. 3D microenvironment as essential element for osteoinduction by biomaterials. Biomaterials. 2005;26: 3565-3575
33. Hing Ka, Annaz B, Saeed S, Revell PaandBuckland T. Microporosity enhances bioactivity of synthetic bone graft substitutes. J Mater Sci Mater Med. 2005;16: 467-75.
34. Reinstorf A, Ruhnow M, Gelinsky M, Pompe W, Hempel U, Wenzel KwandSimon P. Phosphoserine - a convenient compound for modification of calcium phosphate bone cement collagen composites. J Mater Sci Mater Med. 2004;15: 451-455
35. Kasten P, Luginbuhl R, Van Griensven M, Barkhausen T, Krettek C, Bohner MandBosch U. Comparison of human bone marrow stromal cells seeded on calcium-deficient hydroxyapatite, beta-tricalcium phosphate and demineralized bone matrix. Biomaterials. 2003;24: 2593-603.
36. Hempel U, Reinstorf A, Poppe M, Fischer U, Gelinsky M, Pompe WandWenzel Kw. Proliferation and differentiation of osteoblasts on Biocement D modified with collagen type I and citric acid. J Biomed Mater Res B Appl Biomater. 2004;71: 130-143
37. Plachokova As, Van Den Dolder J, Stoelinga PjandJansen Ja. Early effect of platelet-rich plasma on bone healing in combination with an osteoconductive material in rat cranial defects. Clin Oral Implants Res. 2007;18: 244-251
38. Nair Mb, Varma Hk, Menon Kv, Shenoy SjandJohn A. Reconstruction of goat femur segmental defects using triphasic ceramic-coated hydroxyapatite in combination with autologous cells and platelet-rich plasma. Acta Biomater. 2009;5: 1742-1755
39. Kasten P, Vogel J, Luginbuhl R, Niemeyer P, Weiss S, Schneider S, Kramer M, Leo AandRichter W. Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics. Cells Tissues Organs. 2006; 183: 68-79. (Pubitemid 44610330)
40. Kasten P, Vogel J, Beyen I, Weiss S, Niemeyer P, Leo AandLuginbuhl R. Effect of platelet-rich plasma on the in vitro proliferation and osteogenic differentiation of human mesenchymal stem cells on distinct calcium phosphate scaffolds: the specific surface area makes a difference. J Biomater Appl. 2008;23: 169-188
41. Kilian O, Flesch I, Wenisch S, Taborski B, Jork A, Schnettler RandJonuleit T. Effects of platelet growth factors on human mesenchymal stem cells and human endothelial cells in vitro. Eur J Med Res. 2004;9: 337-344