Endogenous melatonin is not obligatory for the regulation of the rat sleep-wake cycle

Sleep

Volumn 33, Issue 6, 2010, Pages 833-840

  Fisher, Simon P ^a,b   Sugden, David ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Melatonin; Pinealectomy; Radiotelemetry; Rat; Sleep

Indexed keywords

6 HYDROXYMELATONIN SULFATE; MELATONIN; SULFATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE MONITORING; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORE TEMPERATURE; ELECTROENCEPHALOGRAM; ELECTROMYOGRAM; HIPPOCAMPUS; HORMONE ACTION; LOCOMOTION; MALE; NONHUMAN; NONREM SLEEP; PINEALECTOMY; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; REM SLEEP; SLEEP PARAMETERS; SLEEP WAKING CYCLE; THETA RHYTHM; URINARY EXCRETION;

EID: 77953175426     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.1093/sleep/33.6.833     Document Type: Article

References (47)

1. Zhdanova IV. Melatonin as a hypnotic: pro. Sleep Med Rev 2005;9:51-65.
2. Van Den Heuvel CJ, Ferguson MA, Macchi MM, Dawson D. Melatonin as a hypnotic: con. Sleep Med Mev 2005;9:71-80.
3. Wurtman R. Ramelteon: a novel treatment for the treatment of insomnia. Expert Rev Neurother 2006;6:957-964
4. Montgomery SA. Major depressive disorders: clinical efficacy and tolerability of agomelatine, a new melatonergic agonist. Eur Neuropsychopharmacol 2006;16:.633-638
5. Rajaratnam SM, Polymeropoulos MH, Fischer D., Scott CH, Birznieks G, Kleitman EB. The melatonin agonist VEC-162 immediately phase advances the human circadian system. Sleep 2006;29:A54 0159.
6. Zemlan FP, Mulchahey JJ, Scharf MB, Maylebeen DW, Rosenberg R, Lankford A. The efficacy and safety of the melatonin agonist beta-meth-yl-6- chloromelatonin in primary insomnia: a randomized, placebo-controlled, clinical trial. J Clin Psychiatry 2005;66:384-390
7. Wade A., Ford I, Crawford G, McMahon AD, Nir T, Laudon M, Zisapel N. Efficacy of prolonged release melatonin in insomnia patients aged 55-80 years: quality of sleep and next-day alertness outcomes. Curr Med Res Opin 2007;23:2597-2605. (Pubitemid 350033462)
8. Arendt J, Rajaratnam SM Melatonin and its agonists: an update. Br J Psychiatry 2008;193:267-269
9. Etzioni A, Luboshitzky R, Tiosano D, Ben-Harush M, Goldsher D, Lavie P. Melatonin replacement corrects sleep disturbances in a child with pineal tumor. Neurology 1996;46:261-263
10. Jan J., Tai J, Hahn G, Rothstein RR. Melatonin replacement therapy in a child with a pineal tumor. J Child Neurol 2001;16:139-140
11. Lehmann ED, Cockerell OC, Rudge P. Somnolence associated with melatonin deficiency after pinealectomy. Lancet 1996;347:323.
12. Smith A., Dykens E, Greenberg F. Sleep disturbance in Smith-Magenis syndrome (Del 17 P11-2). Am J Med Genet 1998;81:186-191
13. Gropman A., Duncan W., Smith AC. Neurologic and developmental features of the Smith-Magenis syndrome (del 17p11-2). Pediatr Neurol 2006;34:337-350
14. Zeitzer J., Ayas NT, Shea SA, Brown R, Czeisler CA. Absence of detectable melatonin and preservation of cortisol and thyrotropin rhythms in Tetraplegia. J Clin Endocrinol Metab 2000;85:2189-2196
15. Huber R, Deboer T, Tobler I. Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: Empirical data and simulations. Brain Res 2000;857:8-19. (Pubitemid 30107786)
16. Roseboom PH, Namboodiri MA, Zimonjic DB, et al. Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin Nacetyltransferase. Brain Res Mol Brain Res 1998;63:189-197
17. Rechtschaffen A, Whitehead WE, Whitehead PK, Wincor MZ. Role of the pineal gland in light-off triggering of paradoxical sleep in the rat. Psychophysiology 1969;6:272.
18. Mouret J, Coindet J, Chouvet G. Effect of pinealectomy on sleep stages and rhythms of the male rat. Brain Res 1974;81:97-105.
19. Rendelson WB, Bergmann BM. Effects of pinealectomy on baseline sleep and response to sleep deprivation. Sleep 2001;24:369-373 (Pubitemid 32520809)
20. Kawakami M, Yamaoka S, Yamaguchi T. Influence of light and hormones upon circadian rhythm of EEG slow wave and paradoxical sleep. In: Itoh S, Ogata K, Yoshimura H, eds. Advances in Climatic Physiology. Tokyo, Japan: Igaku Shoin; 1972:349-366
21. Sack RL, Hughes RJ, Edgar DM, Lewy AJ. Sleep-promoting effects of melatonin: at what dose, in whom, under what conditions, and by what mechanisms? Sleep 1997;20:908-915
22. Dollins AB, Zhdanova IV, Wurtman RJ, Lynch HJ, Deng MH. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc Natl Acad Sci USA 1994;91:1824-1828
23. Zhdanova IV, Wurtman RJ, Lynch HJ et al. Sleep-inducing effects of low doses of melatonin ingested in the evening. Clin Pharmacol Ther 1995;57:552-558
24. Hoffman RA, Reiter RJ. Rapid pinealectomy in hamsters and other small rodents. Anat Rec 1965;153:19-21.
25. Fisher ME, Davidson K, Kulla A, Sugden D. Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat. J Pineal Res 2008;45:125-132
26. Aldhous ME, Arendt J Radioimmunoassay for 6-sulphatoxymelatonin in urine using an iodinated tracer. Ann Clin Biochem 1998;25:298-303.
27. Walser M. Assessing renal function from creatinine measurements in adults with chronic renal failure. Am J Kidney Dis 1998;32:23-31. (Pubitemid 28311867)
28. Apple F, Bandt C, Prosch A, Erlandson G, Holmstrom V, Scholen J, Googins M. Creatinine clearance: enzymatic vs Jaffé determinations of creatinine in plasma and urine. Clin Chem 1986;32:388-390 (Pubitemid 17025671)
29. Louis RP, Lee J, Stephenson R. Design and validation of a computer-based sleep-scoring algorithm. J Neurosci Methods 2004;133:71-80. (Pubitemid 38147758)
30. Kennaway DJ. Urinary 6-sulphatoxymelatonin excretory rhythms in laboratory rats: effects of photoperiod and light. Brain Res 1993;603:338-342
31. Cheung PW, McCormack CE. Failure of pinealectomy or melatonin to alter circadian activity rhythm of the rat. Am J Physiol 1982;242:.261-264
32. Spencer F, Shirer HW, Yochim JM. Core temperature in the female rat: effect of pinealectomy or altered lighting. Am J Physiol 1976;231:355-360
33. 1 melatonin receptor subtype in the tail artery of juvenile Wistar rats. Br J Pharmacol 1999;127:987-995
34. Masana MI, Doolen S, Ersahin C, Al-Ghoul WM, Duckles SP, Dubocovich ML, Krause DN. MT(2) melatonin receptors are present and functional in rat caudal artery. J Pharmacol Exp Ther 2002;302:1295-1302.
35. Robert C, Guilpin C, Limoge A. Automated sleep staging systems in rats. J Neurosci Methods 1999;88:111-122
36. 6 receptor antagonists promote sleep in rats. Sleep 2008;31:34-44.
37. Franken P, Tobler I, Borbély AA. Sleep homeostasis in the rat: simulation of the time course of EEG slow-wave activity. Neurosci Lett 1991;130:141-144
38. Buzsáki G. Theta oscillations in the hippocampus. Neuron 2002;33:325-340
39. Winson J. Interspecies differences in the occurrence of theta. Behav Biol 1972;7:479-487
40. Williams LM, Hannah LT, Hastings MH, Maywood ES. Elatonin receptors in the rat brain and pituitary. J Pineal Res 1995;19:173-177
41. Musshoff U, Riewenherm D, Berger E, Fauteck JD, Speckmann EJ. Melatonin receptors in rat hippocampus: molecular and functional investigations. Hippocampus 2002;12:165-173 (Pubitemid 34436701)
42. Savaskan E, Olivieri G, Meier F, et al. Increased melatonin 1a-receptor immunoreactivity in the hippocampus of Alzheimer's disease patients. J Pineal Res 2002;32:59-62.
43. 2 melatonin receptor expression in Alzheimer's disease. J Pineal Res 2005;38:10-16.
44. Wan Q, Man HY, Liu F et al. Differential modulation of GABAA receptor function by Mel1a and Mel1b receptors. Nat Neurosci 1999;2:401-403
45. Wang LM, Suthana NA, Chaudhury D, Weaver DR, Colwell CS Melatonin inhibits hippocampal long-term potentiation. Eur J Neurosci 2005;22:2231-2237 (Pubitemid 41653536)
46. Rawashdeh O, De Borsetti NH, Roman G, Cahill GM. Melatonin suppresses nighttime memory formation in zebrafish. Science 2007;318:1144-1146 (Pubitemid 350134898)
47. De Butte M, Pappas BA. Pinealectomy causes hippocampal CA1 and CA3 cell loss: reversal by melatonin supplementation. Neurobiol Aging 2007;28:306-313 (Pubitemid 44894630)