Endocrine and physiological changes in response to chronic corticosterone: A potential model of the metabolic syndrome in mouse

Endocrinology

Volumn 151, Issue 5, 2010, Pages 2117-2127

  Karatsoreos, Ilia N ^a   Bhagat, Sarah M ^a   Bowles, Nicole P ^a   Weil, Zachary M ^a   Pfaff, Donald W ^a   McEwen, Bruce S ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; DRINKING WATER; INSULIN; LEPTIN; TRIACYLGLYCEROL;

ADRENAL CORTEX ATROPHY; ADRENALECTOMY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORRELATION ANALYSIS; HORMONE BLOOD LEVEL; HYPERPHAGIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; LOCOMOTION; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THYMUS ATROPHY; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; WHITE ADIPOSE TISSUE; ADRENAL GLAND; ANIMAL; ATROPHY; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; ENDOCRINE SYSTEM; GLUCOSE INTOLERANCE; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; PHYSICAL CHEMISTRY; THYMUS;

ADIPOSE TISSUE, WHITE; ADIPOSITY; ADRENAL GLANDS; ANIMALS; ATROPHY; CORTICOSTERONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE SYSTEM; GLUCOSE INTOLERANCE; HYPERPHAGIA; INSULIN; LEPTIN; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PHYSICOCHEMICAL PROCESSES; THYMUS GLAND; TRIGLYCERIDES; WEIGHT GAIN;

EID: 77953170637     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1436     Document Type: Article

References (48)

1. Dallman MF, Pecoraro N, Akana SF, La Fleur SE, Gomez F, Houshyar H, Bell ME, Bhatnagar S, Laugero KD, Manalo S 2003 Chronic stress and obesity: a new view of "comfort food." Proc Natl Acad Sci USA 100:11696-11701
2. Nieuwenhuizen AG, Rutters F 2008 The hypothalamic-pituitary-adrenal-axis in the regulation of energy balance. Physiol Behav 94:169-177
3. Hill MN, Carrier EJ, Ho WS, Shi L, Patel S, Gorzalka BB, Hillard CJ 2008 Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. Hippocampus 18:221-226
4. Lussier AL, Caruncho HJ, Kalynchuk LE 2009 Repeated exposure to corticosterone, but not restraint, decreases the number of reelin-positive cells in the adult rat hippocampus. Neurosci Lett 460:170-174
5. Magariños AM, McEwen BS 1995 Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors. Neuroscience 69:89-98
6. Björntorp P, Rosmond R 2000 Obesity and cortisol. Nutrition 16:924-936
7. Bjorntorp P, Rosmond R 2000 The metabolic syndrome-a neuroendocrine disorder? Br J Nutr 83(Suppl 1):S49-S57
8. Minami I, Tateno T, Yoshimoto T, Doi M, Izumiyama H, Akashi T, Hirata Y 2006 Subclinical Cushings disease with amelioration of metabolic comorbidities after removal of pituitary tumor. Intern Med 45:1231-1235
9. Schuff KG 2003 Issues in the diagnosis of Cushing's syndrome for the primary care physician. Prim Care 30:791-799
10. Vogelzangs N, Suthers K, Ferrucci L, Simonsick EM, Ble A, Schrager M, Bandinelli S, Lauretani F, Giannelli SV, Penninx BW 2007 Hypercortisolemic depression is associated with the metabolic syndrome in late-life. Psychoneuroendocrinology 32:151-159
11. Vogelzangs N, Penninx BW 2007 Cortisol and insulin in depression and metabolic syndrome. Psychoneuroendocrinology 32:856
12. Muhtz C, Zyriax BC, Klähn T, Windler E, Otte C 2009 Depressive symptoms and metabolic risk: effects of cortisol and gender. Psychoneuroendocrinology 34:1004-1011
13. Rosenzweig JL, Ferrannini E, Grundy SM, Haffner SM, Heine RJ, Horton ES, Kawamori R 2008 Primary prevention of cardiovascular disease and type 2 diabetes in patients at metabolic risk: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 93:3671-3689
14. Grundy SM, Brewer Jr HB, Cleeman JI, Smith Jr SC, Lenfant C 2004 Definition of metabolic syndrome: report of the national heart, lung, and blood institute/american heart association conference on scientific issues related to definition. Circulation 109:433-438
15. Yaneva M, Mosnier-Pudar H, Dugué MA, Grabar S, Fulla Y, Bertagna X 2004 Midnight salivary cortisol for the initial diagnosis of Cushing's syndrome of various causes. J Clin Endocrinol Metab 89:3345-3351
16. Warne JP, Akana SF, Ginsberg AB, Horneman HF, Pecoraro NC, Dallman MF 2009 Disengaging insulin from corticosterone: roles of each on energy intake and disposition. Am J Physiol Regul Integr Comp Physiol 296:R1366-R1375
17. la Fleur SE, Akana SF, Manalo SL, Dallman MF 2004 Interaction between corticosterone and insulin in obesity: regulation of lard intake and fat stores. Endocrinology 145:2174-2185
18. Christ-Crain M, Kola B, Lolli F, Fekete C, Seboek D, Wittmann G, Feltrin D, Igreja SC, Ajodha S, Harvey-White J, Kunos G, Müller B, Pralong F, Aubert G, Arnaldi G, Giacchetti G, Boscaro M, Grossman AB, Korbonits M 2008 AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing's syndrome. FASEB J 22:1672-1683
19. Banks AS, Davis SM, Bates SH, Myers Jr MG 2000 Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 275:14563-14572
20. Wolf G 2002 Glucocorticoids in adipocytes stimulate visceral obesity. Nutr Rev 60:148-151
21. Sjögren J, Weck M, Nilsson A, Ottosson M, Björntorp P 1994 Glucocorticoid hormone binding to rat adipocytes. Biochim Biophys Acta 1224:17-21
22. Rebuffé-Scrive M, Walsh UA, McEwen B, Rodin J 1992 Effect of chronic stress and exogenous glucocorticoids on regional fat distribution and metabolism. Physiol Behav 52:583-590
23. Strack AM, Bradbury MJ, Dallman MF 1995 Corticosterone decreases nonshivering thermogenesis and increases lipid storage in brown adipose tissue. Am J Physiol 268:R183-R191
24. Vaisse C, Halaas JL, Horvath CM, Darnell Jr JE, Stoffel M, Friedman JM 1996 Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet 14:95-97
25. Friedman JM 1997 Leptin, leptin receptors and the control of body weight. Eur J Med Res 2:7-13
26. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546
27. Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR 2008 Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab 7:125-134
28. Haas JT, Biddinger SB 2009 Dissecting the role of insulin resistance in the metabolic syndrome. Curr Opin Lipidol 20:206-210
29. Larsson H, Ahrén B 1996 Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women. J Clin Endocrinol Metab 81:4428-4432
30. Miell JP, Englaro P, Blum WF 1996 Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects. Horm Metab Res 28:704-707 (Pubitemid 27057920)
31. Russell CD, Petersen RN, Rao SP, Ricci MR, Prasad A, Zhang Y, Brolin RE, Fried SK 1998 Leptin expression in adipose tissue from obese humans: depot-specific regulation by insulin and dexamethasone. Am J Physiol 275:E507-E515
32. Dallman MF, Akana SF, Strack AM, Scribner KS, Pecoraro N, La Fleur SE, Houshyar H, Gomez F 2004 Chronic stress-induced effects of corticosterone on brain: direct and indirect. Ann NY Acad Sci 1018:141-150
33. Dallman MF, Akana SF, Pecoraro NC, Warne JP, la Fleur SE, Foster MT2007 Glucocorticoids, the etiology of obesity and the metabolic syndrome. Curr Alzheimer Res 4:199-204
34. Dallman MF, Akana SF, Strack AM, Hanson ES, Sebastian RJ 1995 The neural network that regulates energy balance is responsive to glucocorticoids and insulin and also regulates HPA axis responsivity at a site proximal to CRF neurons. Ann NY Acad Sci 771:730-742
35. Bell ME, Bhatnagar S, Liang J, Soriano L, Nagy TR, Dallman MF 2000 Voluntary sucrose ingestion, like corticosterone replacement, prevents the metabolic deficits of adrenalectomy. J Neuroendocrinol 12:461-470
36. Bhatnagar S, Bell ME, Liang J, Soriano L, Nagy TR, Dallman MF 2000 Corticosterone facilitates saccharin intake in adrenalectomized rats: does corticosterone increase stimulus salience? J Neuroendocrinol 12:453-460
37. Kolaczynski JW, Goldstein BJ, Considine RV 1997 Dexamethasone, OB gene, and leptin in humans; effect of exogenous hyperinsulinemia. J Clin Endocrinol Metab 82:3895-3897
38. Coll AP, Challis BG, López M, Piper S, Yeo GS, O'Rahilly S 2005 Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids. Diabetes 54:2269-2276
39. Smart JL, Tolle V, Low MJ 2006 Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice. J Clin Invest 116:495-505
40. Magariños AM, McEwen BS 1995 Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors. Neuroscience 69:83-88
41. Blanchard DC, Spencer RL, Weiss SM, Blanchard RJ, McEwen B, Sakai RR 1995 Visible burrow system as a model of chronic social stress: behavioral and neuroendocrine correlates. Psychoneuroendocrinology 20:117-134
42. Armario A, Ortiz R, Balasch J 1984 Effect of crowding on some physiological and behavioral variables in adult male rats. Physiol Behav 32:35-37
43. Ottenweller JE, Servatius RJ, Natelson BH 1994 Repeated stress persistently elevates morning, but not evening, plasma corticosterone levels in male rats. Physiol Behav 55:337-340
44. Gourley SL, Wu FJ, Kiraly DD, Ploski JE, Kedves AT, Duman RS, Taylor JR 2008 Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression. Biol Psychiatry 63:353-359
45. Segall LA, Perrin JS, Walker CD, Stewart J, Amir S 2006 Glucocorticoid rhythms control the rhythm of expression of the clock protein, Period2, in oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats. Neuroscience 140:753-757 (Pubitemid 43767456)
46. Lamont EW, Robinson B, Stewart J, Amir S 2005 The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2. Proc Natl Acad Sci USA 102:4180-4184
47. Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, Reichardt HM, Schütz G, Schibler U 2000 Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science 289:2344-2347
48. Balsalobre A 2002 Clock genes in mammalian peripheral tissues. Cell Tissue Res 309:193-199 (Pubitemid 34744041)