Comparison of absorption of 1-deoxynojirimycin from mulberry water extract in rats

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 11, 2010, Pages 6666-6671

  Kim, Ji Yeon ^a   Kwon, Hye Jin ^a   Jung, Ji Young ^a   Kwon, Hye Young ^a   Baek, Jin Gyeong ^a   Kim, Young Suk ^a   Kwon, Oran ^a  

^a Ewha Womans University   (South Korea)

Author keywords

1 Deoxynojirimycin; Absorption; Bioavailability; Caco 2; Mulberry leaves

Indexed keywords

1 DEOXYNOJIRIMYCIN; PLANT EXTRACT; WATER;

ANIMAL; ARTICLE; CELL STRAIN CACO 2; CHEMISTRY; COMPARATIVE STUDY; HUMAN; MALE; MULBERRY; RAT; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

1-DEOXYNOJIRIMYCIN; ANIMALS; CACO-2 CELLS; HUMANS; MALE; MORUS; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; WATER;

MORUS (ANGIOSPERM); RATTUS;

EID: 77953170403     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf100322y     Document Type: Article

References (24)

1. Asano, N.; Yamashita, T.; Yasuda, K.; Ikeda, K.; Kameda, Y.; Kato, A.; Nash, R. J.; Lee, H. S.; Ryu, K. S. Polyhydroxy alkaloids islated from mulberry trees (Morus alba L.) and silkworms (Bombyx mori L.) J. Agric. Food Chem. 2001, 49, 4208-4213
2. Kimura, T.; Nakagawa, K.; Saito, Y.; Yamagishi, K.; Suzuki, M.; Yamaki, K.; Shinmoto, H.; Miyazawa, T. Determination of 1-deoxynojirimycin in Mulberry leaves using hydrophilic interaction chromatography with evaporative light scattering detection J. Agric. Food Chem. 2004, 52, 1415-1418
3. Nojima, H.; Kimura, I.; Chen, F. J.; Sugihara, Y.; Haruno, M. Antihyperglycemic effects of N-containing sugars from Xanthocercis zambesiaca, Morus bombycis, Aglaonema treubii, and Castranospermum austral in streptozotocin-diabetic mice J. Nat. Prod. 1998, 61, 397-400
4. Kong, W. H.; Oh, S. H.; Ahn, Y. R.; Kim, K. W.; Kim, J. H.; Seo, S. W. Antiobesity effects and improvement of insulin sensitivity by 1-deoxynojirimycin in animal models J. Agric. Food Chem. 2008, 56, 2613-2619
5. Hughes, A. B.; Rudge, A. J. Deoxynojirimycin: synthesis and biological activity Nat. Prod. Rep. 1994, 11, 135-162
6. Lee, S. K.; Hwang, J. Y.; Song, J. H.; Jo, J. R.; Kim, M. J.; Kim, M. E.; Kim, J. I. Inhibitory activity of Euonymus alatus alpha-glucosidase in vitro and in vivo Nutr. Res. Pract. 2007, 1, 184-188
7. Kimura, T.; Nakagawa, K.; Kubota, H.; Kojima, Y.; Goto, Y.; Yamagishi, K.; Oita, S.; Oikawa, S.; Miyazawa, T. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans J. Agric. Food Chem. 2007, 55, 5869-5874
8. Miyahara, C.; Miyazawa, M.; Satoh, S.; Sakai, A.; Mizusaki, S. Inhibitory effects of mulberry leaf extract on postprandial hyperglycemia in normal rats J. Nutr. Sci. Vitaminol. 2004, 50, 161-164
9. Song, W.; Wang, H. J.; Bucheli, P.; Zhang, P. F.; Wei, D. Z.; Lu, Y. H. Phytochemical profiles of different mulberry (Morus sp.) species from China J. Agric. Food Chem. 2009, 57, 9133-9140
10. Chae, J. Y.; Lee, J. Y.; Hoang, I. S.; Whangbo, D.; Choi, P. W.; Lee, W. C.; Kim, J. W.; Kim, S. Y.; Choi, S. W.; Rhee, S. J. Analysis of functional components of leaves of different mulberry cultivars J. Korean Soc. Food Sci. Nutr. 2003, 32, 15-21
11. Faber, E. D.; Oosting, R.; Neefjes, J. J.; Ploegh, H. L.; Meijer, D. K. Distribution and elimination of the glycosidase inhibitors 1-deoxymannojirimycin and N-methyl-1-deoxynojirimycin in the rat in vivo Pharm. Res. 1992, 9, 1442-1450
12. Nakagawa, K.; Kubota, H.; Kimura, T.; Yamashita, S.; Tsuzuki, T.; Oikawa, S.; Miyazawa, T. Occurrence of orally administered mulberry 1-deoxynojirimycin in rat plasma J. Agric. Food Chem. 2007, 55, 8928-8933
13. Hidalgo, I. J.; Raub, T. J.; Borchardt, R. T. Characterization of the human colon adenocarcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability Gastroenterology 1989, 96, 736-749
14. Artursson, P. Cell cultures as models for drug absorption across the intestinal mucosa Crit. Rev. Ther. Drug Carrier Syst. 1991, 8, 305-330
15. Kim, J.; Kim, S.; Lee, H. S.; Kim, I.; Ahn, M. Y.; Ahn, M. Y. Determination of 1-deoxynojirimycin in Morus alba L. leaves by derivatization with 9-fluorenylmethyl chloroformate followed by reversed-phase high-performance liquid chromatography J. Chromatogr., A 2003, 1002, 93-99
16. Knapp, D. R. Carbohydrate. In Handbook of Analytical Derivatization Reactions; John Wiley & Sons: Hoboken, NJ, 1979; pp 539-598.
17. Glahn, R.; Van Campen, D. Iron uptake is enhanced in Caco-2 cell monolayers by cysteine and reduced cysteinyl glycine J. Nutr. 1997, 127, 642-647
18. Deprez, S.; Mila, I.; Huneau, J.; Tome, D.; Scalbert, A. Transport of proanthocyanidin dimer, trimer, and polymer across monolayers of human intestinal epithelial Caco-2 cells Antioxid. Redox Signaling 2001, 3, 957-967
19. Kuo, S. Transepithelial transport and accumulation of flavones in human intestinal Caco-2 cells Life Sci. 1998, 63, 2323-2331
20. Ferruzzi, M.; Failla, M.; Sarama, R. Estimation of carotenoid bioavailability from fresh stir-fried vegetables using an in vitro digestion/Caco-2 cell culture model J. Nutr. Biochem. 2000, 11, 574-580
21. Kopka, J. Current challenges and developments in GC-MS based metabolite profiling technology J. Biotechnol. 2006, 124, 312-322
22. Park, J. M.; Bong, H. Y.; Jeong, H. I.; Kim, Y. K.; Kim, J. Y.; Kwon, O. Postprandial hypoglycemic effect of mulberry leaf in Goto-Kakizaki rats and counterpart control Wistar rats Nutr. Res. Pract. 2009, 3, 272-278
23. Riccardi, G.; Rivellese, A. A. Effects of dietary fiber and carbohydrate on glucose and lipoprotein metabolism in diabetic patients Diabetes Care 1991, 14, 1115-1125
24. Ahr, H. J.; Boberg, M.; Brendel, E.; Krause, H. P.; Steinke, W. Pharmacokinetics of miglitol, absorption, distribution, metabolism, and excretion following administration to rats, dogs, and man Arzneimittelforschung 1997, 47, 734-745