Nanoparticles: A closer look at their dermal effects

Journal of Drugs in Dermatology

Volumn 9, Issue 5, 2010, Pages 475-481

  Choksi, Adrienne N ^a   Poonawalla, Tasneem ^b   Wilkerson, Michael G ^c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; ANTIOXIDANT; CARBON 13; COSMETIC; CYANOACRYLATE DERIVATIVE; LIPID; MANGANESE OXIDE; NANOPARTICLE; POVIDONE IODINE; QUANTUM DOT; REACTIVE OXYGEN METABOLITE; RETINOL; SHAMPOO; SILICATE; SUNSCREEN; TITANIUM DIOXIDE; TOOTHPASTE; ZINC OXIDE; DERMATOLOGICAL AGENT; TITANIUM;

AIR POLLUTION; ANTIGENICITY; ATHEROGENESIS; AUTOIMMUNITY; CENTRAL NERVOUS SYSTEM; CIRCULATION; CYTOTOXICITY; DIFFUSION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; FIBROSIS; FUME; GRANULOMA; HAIR FOLLICLE; HUMAN; INFLAMMATION; INFLAMMATORY INFILTRATE; INGESTION; LANGERHANS CELL; LIPOPHILICITY; LYMPHATIC SYSTEM; MEMBRANE DAMAGE; MICROGLIA; NANOEMULSION; NERVE CELL LESION; NERVE CELL STIMULATION; NERVE FIBER; NEUROTOXICITY; NONHUMAN; OLFACTORY BULB; OXIDATIVE STRESS; PARTICLE SIZE; PARTICULATE MATTER; PROTEIN DEFECT; PROTEIN EXPRESSION; RESPIRATORY SYSTEM; REVIEW; SKIN ABSORPTION; SKIN PENETRATION; SKIN TOXICITY; STRATUM CORNEUM; ULTRAVIOLET RADIATION; ANIMAL; INTRADERMAL DRUG ADMINISTRATION; PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; COSMETICS; DERMATOLOGIC AGENTS; HUMANS; NANOPARTICLES; PERMEABILITY; SKIN ABSORPTION; SUNSCREENING AGENTS; TITANIUM; ZINC OXIDE;

EID: 77953154392     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. Oberdorster G, Oberdorster E, Oberdorster J. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005;113:823-839. (Pubitemid 40984181)
2. MIT Environment, Health, and Safety Office (2006). Potential Risks of Nanomaterials and How to Safely Handle Materials of Uncertain Toxicity. Retrieved September 1st, 2006, from http://web.mit.edu/ENVIRONMENT/ehs/topic/ nanomaterial.html.
3. Meyer M, Kuusi O. Nanotechnology: Generalizations in an interdisciplinary field of science and technology. Intern J Philos Chem. 2002;10:153-168.
4. Yamakoshi Y, Umezawa N, Ryu A, et al. Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-*versus 1O2. J Am Chem Soc. 2003;125:12803-12809.
5. Jenning, V, Gysler A, Schafer-Korting M, Gohla SH. Vitamin A loaded solid lipid nanoparticles for topical used properties and drug targeting to the upper skin. EJ Pharm and Biopharm. 2000;49:211-218. (Pubitemid 30229868)
6. Nasir, A. Nanotechnology and Dermatology. Presentation at the American Academy of Dermatology, July 2008.
7. Borm P, Robbins D, Haubold S, et al. The potential risks of nanomaterials: A review carried out for ECETOC. Part Fibre Toxicol. 2006;3:11.
8. Oberdorster G. Toxicology of ultrafine particles: In vivo studies. Philos Trans R Soc Lond A. 2000;358:2719-2740.
9. Oberdorster G, Sharp Z, Atudorei V, et al. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol. 2004;16:437-445. (Pubitemid 38685135)
10. Feikert T, Mercer P, Corson N, et al. Inhaled solid ultrafine particles (UFP) are efficiently translocated via neuronal naso-olfactory pathways. Toxicologist. 2004;78:435-436.
11. Long T, Saleh N, Tilton R, et al. Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): Implications for nanoparticle neurotoxicity. Environ Sci Technol. 2006;40:4346-4352. (Pubitemid 44092366)
12. Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism. Prog Neurobiol. 2005;76:77-98. (Pubitemid 41242883)
13. Colton CA, Chernyshev ON, Gilbert DL, Vitek MP. Microglial contribution to oxidative stress in Alzheimer's disease. Ann NY Acad Sci. 2000;899:292-307. (Pubitemid 30352795)
14. Liu B, Hong JS. Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther. 2003;304:1-7. (Pubitemid 36008905)
15. Lomer MC, Thompson RP, Powell JJ. Fine and ultrafine particles of the diet: Influence on the mucosal immune response and association with Crohn's disease. Proc Nutr Soc. 2002;61:123-130. (Pubitemid 34173020)
16. Jani PU, McCarthy DE, Florence AT. Titanium dioxide (rutile) particles uptake from the rat GI tract and translocation to systemic organs after oral administration. J Pharm. 1994;105:157-168. (Pubitemid 24097168)
17. Bockmann J, Lahl H, Eckert T, Unterhalt B. Titanium blood levels of dialysis patients compared to healthy volunteers. Pharmazie. 2000;55:468. (Pubitemid 30433148)
18. nd, 2009 from http://www.nanotechproject.org/inventories/.
19. Nel A, Xia T, Li N. Toxic potential of materials at the nanolevel. Science. 2006;311:622-627. (Pubitemid 43191298)
20. Vogt A, Combadiere B, Hadem S, et al. 40nm, but not 750 or 1,500nm, nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin. J Invest Dermatol. 2006;126:1316-1322. (Pubitemid 43997914)
21. Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA. Penetration of intact skin by quantum dots with diverse physicochemical properties. Toxicol Sci. 2006;91:159-165.
22. Sayes CM, Wahi R, Kurian PA, et al. Correlating nanoscale titania structure with toxicity: A cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. Toxicol Sci. 2006;92:174-185. (Pubitemid 43994876)
23. Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA. Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes. J Invest Dermatol. 2006;10:1-11.
24. Wamer WG, Yin JJ, Wei RR. Oxidative change to nucleic acids photosensitized by titanium dioxide. Free Radical Biol Med. 1997;23:851-858. (Pubitemid 27402610)
25. Xia T, Kovochich M, Brant J, et al. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Letters. 2006;6:1794-1807. (Pubitemid 44327550)
26. Lademann J, Weigmann H, Rickmeyer C, et al. Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Skin Pharmacol Appl Skin Physiol. 1999;12:247-256. (Pubitemid 29401452)
27. Pflucker F, Wendel V, Hohenberg H, et al. The human stratum corneum layer: An effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide. Skin Pharmacol Appl Skin Physiol. 2001;14 Suppl 1:92-97. (Pubitemid 34299170)
28. Gamer AO, Leibold E, Van Ravenzwaay B. The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin. Toxicol in Vitro. 2006;20(3):301-7. (Pubitemid 43343759)
29. Cross SE, Innes B, Roberts MS, et al. Human skin penetration of sunscreen nanoparticles: In-vitro assessment of a novel micronized zinc oxide formulation. Skin Pharmacol Physiol. 2007;20(3):148-154. (Pubitemid 46788286)
30. Tinkle SS, Antonini JM, Rich BA, et al. Skin as a route of exposure and sensitization in chronic berrylium disease. Environ Health Perspect. 2003;111:1202-1208. (Pubitemid 36939402)
31. Nohynek GJ, Dufour EK, Roberts MS. Nanotechnology, cosmetics and the skin: Is there a health risk? Skin Pharmacol Physiol. 2008;21:136-149. (Pubitemid 351793742)