Is higher prevalence of cervical intraepithelial neoplasia in women with lupus due to immunosuppression?

Journal of Clinical Rheumatology

Volumn 16, Issue 4, 2010, Pages 153-157

  Klumb, Evandro M ^a   Araújo, Mario L ^b   Jesus, Guilherme R ^b   Santos, Denise B ^b   Oliveira, Albanita V ^b   Albuquerque, Elisa M N ^a   Macedo, Jacyara M B ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Department of Pathology ^*  (Brazil)

Author keywords

Cervical cancer; Cervical dysplasia; Immunosuppression; Neoplasia; Systemic lupus erythematosus

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ADULT; ARTICLE; CANCER GRADING; CONTROLLED STUDY; CYTOPATHOLOGY; FEMALE; HUMAN; IMMUNE DEFICIENCY; INCIDENCE; LONG TERM CARE; LUPUS ERYTHEMATOSUS; MAJOR CLINICAL STUDY; MORTALITY; NONPARAMETRIC TEST; PARAMETRIC TEST; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SOCIAL CLASS; UTERINE CERVIX CARCINOMA IN SITU;

ADULT; BRAZIL; CASE-CONTROL STUDIES; CERVICAL INTRAEPITHELIAL NEOPLASIA; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSIVE AGENTS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MIDDLE AGED; ODDS RATIO; PREVALENCE; TIME FACTORS; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 77953136298     PISSN: 10761608     EISSN: None     Source Type: Journal    
DOI: 10.1097/RHU.0b013e3181df5261     Document Type: Article

References (30)

1. Bernatsky S, Boivin JF, Joseph L, et al. Race/ethnicity and cancer occurrence in systemic lupus erythematosus. Arthritis Rheum. 2005;53:781-784. (Pubitemid 41463845)
2. Cibere J, Sibley J, Haga M. Systemic lupus erythematosus and the risk of malignancy. Lupus. 2001;19:394-400.
3. Bernatsky S, Ramsey-Goldman R, Gordon C, et al. Factors associated with abnormal Pap results in systemic lupus erythematosus. Rheumatology. 2004;43:1386-1389.
4. Bosh FX, Lorincz A, Munoz M, et al. The causal relationship between human papillomavirus and cervical cancer. J Clin Pathol. 2002;55:244-265. (Pubitemid 34293391)
5. Grinsztejn B, Veloso VG, Levi JE, et al. Factors associated with increased prevalence of human papillomavirus infection in a cohort of HIV-infected Brazilian women. Int J Infect Dis. 2009;13:72-80.
6. Instituto Nacional de Cancer, Ministerio da Saude, Brasil. Estimativa de incidencia e mortalidade por cancer no Brasil. 2008. Available at: http://www.inca.gov. br.
7. Moscicki AB, Hills N, Shiboski S, et al. Risks for incident human papillomavirus infection and low-grade squamous intraepithelial lesion development in young females. JAMA. 2001;285:2995-3002.
8. Carvalho MO, Carestiato FN, Perdigao PH, et al. Human papillomavirus infection in Rio de Janeiro, Brazil: a retrospective study. Braz J Infect Dis. 2005;9:398-404.
9. Steben M, Duarte-Franco E. Human papillomavirus infection: epidemiology and pathophysiology. Gynecol Oncol. 2007;107: S2-S5.
10. Nanda K, McCrory DC, Myers ER, et al. Accuracy of the Papanicolaou test in screening for and follow-up of cervical cytologic abnormalities: a systematic review. Ann Intern Med. 2000;132:810-819.
11. Lindeque BG. Management of cervical premalignant lesions. Best Pract Res Clin Obstet Gynaecol. 2005;19:545-561.
12. Hochberg MC. Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum. 1997;40:1725.
13. Gladman D, Ginzler E, Goldsmith C, et al. The development and initial validation of the systemic lupus international collaborating clinics/American College of Rheumatology damage index for the systemic lupus erythematosus. Arthritis Rheum. 1996;39:363-369.
14. Solomon D, Davey D, Kurman R, et al. Forum Group Members; Bethesda 2001 Workshop. The 2001 Bethesda System: terminology for reporting results of cervical cytology. JAMA. 2002;287:2114-2119.
15. Canoso JJ, Cohen AS. Malignancy in a series of 70 patients with systemic lupus erythematosus. Arthritis Rheum. 1974;17:383-390.
16. Berthier S, Mougin C, Vercherin P, et al. Existe-t-il un risqué particulier lié aux infections à papillomavirus chez les femmes lupiques? Rev Méd Interne. 1999;20:128-132.
17. Bateman H, Yazici Y, Leff L, et al. Increased cervical dysplasia in intravenous cyclophosphamide treated patients with SLE: a preliminary study. Lupus. 2000;9:542-544.
18. Dhar JP, Essenmacher L, Ager J, et al. Ominous cervical cytopathology in women with lupus. Int J Gynaecol Obstet. 2005;89:295-296.
19. Tam LS, Chan AY, Chan PK, et al. Increased prevalence of squamous intraepithelial lesions in systemic lupus erythematosus. Arthritis Rheum. 2004;50:3619-3625.
20. Blumenfeld Z, Lorber M, Yoffe N, et al. Systemic lupus erythematosus: predisposition for uterine cervical dysplasia. Lupus. 1994;3:59-61.
21. Nyberg G, Eriksson O, Westberg NG. Increased incidence of cervical atypia in women with systemic lupus erythematosus treated with chemotherapy. Arthritis Rheum. 1981;24:648-650.
22. Elias A, Linthorst G, Bekker B, et al. The significance of endocervical cells in diagnosis of cervical epithelial changes. Acta Oncol. 1983;27:225-229.
23. Benard VB, Lee NC, Piper M, et al. Race-specific results of Papanicolaou testing and the rate of cervical neoplasia in the National Breast and Cervical Cancer Early Detection Program, 1991-1998 (United States). Cancer Causes Control. 2001;12:61-68.
24. D'ottaviano-Morelli MG, Zeferino L, Cecatti JZ, et al. Prevalence of intraepithelial neoplasia and invasive carcinoma based on cytological screening in the region of Campinas, São Paulo, Brazil. Cad Saude Publica. 2004;20:153-159.
25. Thuler LC, Zardo LM, Zeferino LC. Perfil dos laboratórios de citopatologia do Sistema Ú nico de Saúde. J Bras Patol Med Lab. 2007;43:103-114.
26. Kjellberg L, Hallmans G, Ahren AM, et al. Smoking, diet, pregnancy and oral contraceptive use as risk factors for cervical intra-epithelial neoplasia in relation to human papillomavirus infection. Br J Cancer. 2000;82:1332-1338.
27. Deacon JM, Evans CD, Yule R, et al. Sexual behavior and smoking as determinants of cervical HPV infection and of CIN3 among those infected: a case-control study nested within the Manchester cohort. Br J Cancer. 2000;83:1565-1572.
28. Olsen AO, Dillner J, Skrondal A, et al. Combined effect of smoking and human papillomavirus type 16 infection in cervical carcinogenesis. Epidemiology. 1998;9:346-349.
29. Ognenovski VM, Marder W, Somers E, et al. Increased incidence of cervical intraepithelial neoplasia in women with systemic lupus erythematosus treated with intravenous cyclophosphamide. J Rheumatol. 2004;31:1763-1767.
30. American College of Obstetricians and Gynecologists. Cervical cytology screening, ACOG Practice Bulletin no. 45. Obstet Gynecol. 2003;102:417-427.