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Volumn 10, Issue 12, 2010, Pages 1509-1517

Microfluidics-enabled phenotyping, imaging, and screening of multicellular organisms

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[No Author keywords available]

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EID: 77953112590     PISSN: 14730197     EISSN: 14730189     Source Type: Journal    
DOI: 10.1039/b927258e     Document Type: Review
Times cited : (90)

References (53)
  • 1
    • 33747090983 scopus 로고    scopus 로고
    • Control and detection of chemical reactions in microfluidic systems
    • A. J. deMello Control and detection of chemical reactions in microfluidic systems Nature 2006 442 7101 394 402
    • (2006) Nature , vol.442 , Issue.7101 , pp. 394-402
    • Demello, A.J.1
  • 3
    • 33747133014 scopus 로고    scopus 로고
    • Developing optofluidic technology through the fusion of microfluidics and optics
    • D. Psaltis S. R. Quake C. H. Yang Developing optofluidic technology through the fusion of microfluidics and optics Nature 2006 442 7101 381 386
    • (2006) Nature , vol.442 , Issue.7101 , pp. 381-386
    • Psaltis, D.1    Quake, S.R.2    Yang, C.H.3
  • 4
    • 33747117373 scopus 로고    scopus 로고
    • The origins and the future of microfluidics
    • G. M. Whitesides The origins and the future of microfluidics Nature 2006 442 7101 368 373
    • (2006) Nature , vol.442 , Issue.7101 , pp. 368-373
    • Whitesides, G.M.1
  • 5
    • 33747086959 scopus 로고    scopus 로고
    • Et al., Microfluidic diagnostic technologies for global public health
    • P. Yager et al., Microfluidic diagnostic technologies for global public health Nature 2006 442 7101 412 418
    • (2006) Nature , vol.442 , Issue.7101 , pp. 412-418
    • Yager, P.1
  • 6
    • 27744466522 scopus 로고    scopus 로고
    • Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans
    • Y. Zhang H. Lu C. I. Bargmann Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans Nature 2005 438 7065 179 184
    • (2005) Nature , vol.438 , Issue.7065 , pp. 179-184
    • Zhang, Y.1    Lu, H.2    Bargmann, C.I.3
  • 7
    • 3142674291 scopus 로고    scopus 로고
    • Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue
    • J. M. Gray et al., Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue Nature 2004 430 6997 317 322
    • (2004) Nature , vol.430 , Issue.6997 , pp. 317-322
    • Gray, J.M.1
  • 8
    • 34548361558 scopus 로고    scopus 로고
    • Microfluidics for in vivo imaging of neuronal and behavioural activity in Caenorhabditis elegans
    • N. Chronis M. Zimmer C. I. Bargmann Microfluidics for in vivo imaging of neuronal and behavioural activity in Caenorhabditis elegans Nat. Methods 2007 4 727 731
    • (2007) Nat. Methods , vol.4 , pp. 727-731
    • Chronis, N.1    Zimmer, M.2    Bargmann, C.I.3
  • 9
    • 17844376743 scopus 로고    scopus 로고
    • Et al., Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidics
    • E. M. Lucchetta et al., Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidics Nature 2005 434 7037 1134 1138
    • (2005) Nature , vol.434 , Issue.7037 , pp. 1134-1138
    • Lucchetta, E.M.1
  • 10
    • 33645528214 scopus 로고    scopus 로고
    • Characterization of the local temperature in space and time around a developing Drosophila embryo in a microfluidic device
    • E. M. Lucchetta M. S. Munson R. F. Ismagilov Characterization of the local temperature in space and time around a developing Drosophila embryo in a microfluidic device Lab Chip 2006 6 2 185 190
    • (2006) Lab Chip , vol.6 , Issue.2 , pp. 185-190
    • Lucchetta, E.M.1    Munson, M.S.2    Ismagilov, R.F.3
  • 11
    • 34548348981 scopus 로고    scopus 로고
    • Et al., Microfluidic self-assembly of live Drosophila embryos for versatile high-throughput analysis of embryonic morphogenesis
    • G. T. Dagani et al., Microfluidic self-assembly of live Drosophila embryos for versatile high-throughput analysis of embryonic morphogenesis Biomed. Microdevices 2007 9 5 681 694
    • (2007) Biomed. Microdevices , vol.9 , Issue.5 , pp. 681-694
    • Dagani, G.T.1
  • 12
    • 65649093684 scopus 로고    scopus 로고
    • Et al., SU-8 force sensing pillar arrays for biological measurements
    • J. C. Doll et al., SU-8 force sensing pillar arrays for biological measurements Lab Chip 2009 9 10 1449 1454
    • (2009) Lab Chip , vol.9 , Issue.10 , pp. 1449-1454
    • Doll, J.C.1
  • 13
    • 36849087277 scopus 로고    scopus 로고
    • Analysis of nematode mechanics by piezoresistive displacement clamp
    • S. J. Park M. B. Goodman B. L. Pruitt Analysis of nematode mechanics by piezoresistive displacement clamp Proc. Natl. Acad. Sci. U. S. A. 2007 104 17376 17381
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 17376-17381
    • Park, S.J.1    Goodman, M.B.2    Pruitt, B.L.3
  • 14
    • 33846937302 scopus 로고    scopus 로고
    • Maze exploration and learning in C-elegans
    • J. H. Qin A. R. Wheeler Maze exploration and learning in C-elegans Lab Chip 2007 7 2 186 192
    • (2007) Lab Chip , vol.7 , Issue.2 , pp. 186-192
    • Qin, J.H.1    Wheeler, A.R.2
  • 15
    • 34250173488 scopus 로고    scopus 로고
    • Et al., Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans
    • D. Dupuy et al., Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans Nat. Biotechnol. 2007 25 663 668
    • (2007) Nat. Biotechnol. , vol.25 , pp. 663-668
    • Dupuy, D.1
  • 16
    • 50249096667 scopus 로고    scopus 로고
    • Et al., Artificial dirt: Microfluidic substrates for nematode neurobiology and behaviour
    • S. R. Lockery et al., Artificial dirt: Microfluidic substrates for nematode neurobiology and behaviour J. Neurophysiol. 2008 99 6 3136 3143
    • (2008) J. Neurophysiol. , vol.99 , Issue.6 , pp. 3136-3143
    • Lockery, S.R.1
  • 17
    • 49649110940 scopus 로고    scopus 로고
    • Et al., Enhanced Caenorhabditis elegans locomotion in a structured microfluidic environment
    • S. Park et al., Enhanced Caenorhabditis elegans locomotion in a structured microfluidic environment PLoS One 2008 3 6 e2550
    • (2008) PLoS One , vol.3 , Issue.6 , pp. 2550
    • Park, S.1
  • 18
    • 61849133344 scopus 로고    scopus 로고
    • Et al., Neurons Detect Increases and Decreases in Oxygen Levels Using Distinct Guanylate Cyclases
    • M. Zimmer et al., Neurons Detect Increases and Decreases in Oxygen Levels Using Distinct Guanylate Cyclases Neuron 2009 61 6 865 879
    • (2009) Neuron , vol.61 , Issue.6 , pp. 865-879
    • Zimmer, M.1
  • 19
    • 62649147296 scopus 로고    scopus 로고
    • Microsystems for controlled genetic perturbation of live Drosophila embryos: RNA interference, development robustness and drug screening
    • J. R. Fakhoury J. C. Sisson X. J. Zhang Microsystems for controlled genetic perturbation of live Drosophila embryos: RNA interference, development robustness and drug screening Microfluid. Nanofluid. 2009 6 3 299 313
    • (2009) Microfluid. Nanofluid. , vol.6 , Issue.3 , pp. 299-313
    • Fakhoury, J.R.1    Sisson, J.C.2    Zhang, X.J.3
  • 20
    • 70349314212 scopus 로고    scopus 로고
    • Automated high-throughput cell microsurgery on-chip
    • K. Chung H. Lu Automated high-throughput cell microsurgery on-chip Lab Chip 2009 9 19 2764 2766
    • (2009) Lab Chip , vol.9 , Issue.19 , pp. 2764-2766
    • Chung, K.1    Lu, H.2
  • 21
    • 46249092235 scopus 로고    scopus 로고
    • Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans
    • K. H. Chung M. M. Crane H. Lu Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans Nat. Methods 2008 5 7 637 643
    • (2008) Nat. Methods , vol.5 , Issue.7 , pp. 637-643
    • Chung, K.H.1    Crane, M.M.2    Lu, H.3
  • 23
    • 27644513652 scopus 로고    scopus 로고
    • Et al., Microoptical characterization and modeling of positioning forces on drosophila embryos self-assembled in two-dimensional arrays
    • X. J. Zhang et al., Microoptical characterization and modeling of positioning forces on drosophila embryos self-assembled in two-dimensional arrays J. Microelectromech. Syst. 2005 14 5 1187 1197
    • (2005) J. Microelectromech. Syst. , vol.14 , Issue.5 , pp. 1187-1197
    • Zhang, X.J.1
  • 24
    • 33746566454 scopus 로고    scopus 로고
    • Automated MEMS-based Drosophila embryo injection system for high-throughput RNAi screens
    • S. Zappe et al., Automated MEMS-based Drosophila embryo injection system for high-throughput RNAi screens Lab Chip 2006 6 8 1012 1019
    • (2006) Lab Chip , vol.6 , Issue.8 , pp. 1012-1019
    • Zappe, S.1
  • 25
    • 41149117090 scopus 로고    scopus 로고
    • A fully automated robotic system for microinjection of zebrafish embryos
    • W. Wang et al., A Fully Automated Robotic System for Microinjection of Zebrafish Embryos PLoS One 2007 2 9 e862
    • (2007) PLoS One , vol.2 , Issue.9 , pp. 862
    • Wang, W.1
  • 26
    • 38849128729 scopus 로고    scopus 로고
    • Automating fruit fly Drosophila embryo injection for high throughput transgenic studies
    • E. Cornell et al., Automating fruit fly Drosophila embryo injection for high throughput transgenic studies Rev. Sci. Instrum. 2008 79 1 013705
    • (2008) Rev. Sci. Instrum. , vol.79 , Issue.1 , pp. 013705
    • Cornell, E.1
  • 27
    • 35548978574 scopus 로고    scopus 로고
    • A microfabricated array of clamps for immobilizing and imaging C. elegans
    • S. E. Hulme et al., A microfabricated array of clamps for immobilizing and imaging C. elegans Lab Chip 2007 7 11 1515 1523
    • (2007) Lab Chip , vol.7 , Issue.11 , pp. 1515-1523
    • Hulme, S.E.1
  • 28
    • 76949108196 scopus 로고    scopus 로고
    • Lifespan-on-a-chip: Microfluidic chambers for performing lifelong observation of C. elegans
    • S. E. Hulme et al., Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans Lab Chip 2010 10 5 589 97
    • (2010) Lab Chip , vol.10 , Issue.5 , pp. 589-597
    • Hulme, S.E.1
  • 29
    • 34548074407 scopus 로고    scopus 로고
    • Micro fluid segment technique for screening and development studies on Danio rerio embryos
    • A. Funfak et al., Micro fluid segment technique for screening and development studies on Danio rerio embryos Lab Chip 2007 7 9 1132 1138
    • (2007) Lab Chip , vol.7 , Issue.9 , pp. 1132-1138
    • Funfak, A.1
  • 30
    • 43149111583 scopus 로고    scopus 로고
    • Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms
    • J. Clausell-Tormos et al., Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms Chem. Biol. 2008 15 5 427 437
    • (2008) Chem. Biol. , vol.15 , Issue.5 , pp. 427-437
    • Clausell-Tormos, J.1
  • 31
    • 52649089822 scopus 로고    scopus 로고
    • Droplet-based microfluidic system for individual Caenorhabditis elegans assay
    • W. W. Shi et al., Droplet-based microfluidic system for individual Caenorhabditis elegans assay Lab Chip 2008 8 9 1432 1435
    • (2008) Lab Chip , vol.8 , Issue.9 , pp. 1432-1435
    • Shi, W.W.1
  • 32
    • 1642351216 scopus 로고    scopus 로고
    • Geometrically Mediated Breakup of Drops in Microfluidic Devices
    • D. R. Link et al., Geometrically Mediated Breakup of Drops in Microfluidic Devices Phys. Rev. Lett. 2004 92 5 54503
    • (2004) Phys. Rev. Lett. , vol.92 , Issue.5 , pp. 54503
    • Link, D.R.1
  • 33
    • 17644415370 scopus 로고    scopus 로고
    • Monodisperse double emulsions generated from a microcapillary device
    • A. S. Utada et al., Monodisperse double emulsions generated from a microcapillary device Science 2005 308 5721 537 541
    • (2005) Science , vol.308 , Issue.5721 , pp. 537-541
    • Utada, A.S.1
  • 34
    • 35348873762 scopus 로고    scopus 로고
    • Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution
    • C. B. Rohde et al., Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution Proc. Natl. Acad. Sci. U. S. A. 2007 104 35 13891 13895
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , Issue.35 , pp. 13891-13895
    • Rohde, C.B.1
  • 35
    • 44349084574 scopus 로고    scopus 로고
    • Femtosecond laser nanoaxotomy lab-on-achip for in vivo nerve regeneration studies
    • S. X. Guo et al., Femtosecond laser nanoaxotomy lab-on-achip for in vivo nerve regeneration studies Nat. Methods 2008 5 6 531 533
    • (2008) Nat. Methods , vol.5 , Issue.6 , pp. 531-533
    • Guo, S.X.1
  • 36
    • 42549105368 scopus 로고    scopus 로고
    • Sub-cellular precision on-chip small-animal immobilization, multi-photon imaging and femtosecond-laser manipulation
    • F. Zeng C. B. Rohde M. F. Yanik Sub-cellular precision on-chip small-animal immobilization, multi-photon imaging and femtosecond-laser manipulation Lab Chip 2008 8 5 653 656
    • (2008) Lab Chip , vol.8 , Issue.5 , pp. 653-656
    • Zeng, F.1    Rohde, C.B.2    Yanik, M.F.3
  • 37
    • 57449100452 scopus 로고    scopus 로고
    • CO2 and compressive immobilization of C. elegans on-chip
    • T. V. Chokshi A. Ben-Yakar N. Chronis CO2 and compressive immobilization of C. elegans on-chip Lab Chip 2009 9 1 151 157
    • (2009) Lab Chip , vol.9 , Issue.1 , pp. 151-157
    • Chokshi, T.V.1    Ben-Yakar, A.2    Chronis, N.3
  • 38
    • 57449110162 scopus 로고    scopus 로고
    • Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system
    • M. M. Crane K. Chung H. Lu Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system Lab Chip 2009 9 1 38 40
    • (2009) Lab Chip , vol.9 , Issue.1 , pp. 38-40
    • Crane, M.M.1    Chung, K.2    Lu, H.3
  • 39
    • 54049088907 scopus 로고    scopus 로고
    • Single-synapse ablation and long-term imaging in live C. elegans
    • P. B. Allen et al., Single-synapse ablation and long-term imaging in live C. elegans J. Neurosci. Methods 2008 173 1 20 26
    • (2008) J. Neurosci. Methods , vol.173 , Issue.1 , pp. 20-26
    • Allen, P.B.1
  • 40
    • 0034711410 scopus 로고    scopus 로고
    • From micro- to nanofabrication with soft materials
    • S. R. Quake A. Scherer From micro- to nanofabrication with soft materials Science 2000 290 5496 1536 1540
    • (2000) Science , vol.290 , Issue.5496 , pp. 1536-1540
    • Quake, S.R.1    Scherer, A.2
  • 41
    • 0034615958 scopus 로고    scopus 로고
    • Monolithic microfabricated valves and pumps by multilayer soft lithography
    • M. A. Unger et al., Monolithic microfabricated valves and pumps by multilayer soft lithography Science 2000 288 5463 113 116
    • (2000) Science , vol.288 , Issue.5463 , pp. 113-116
    • Unger, M.A.1
  • 42
    • 0032738825 scopus 로고    scopus 로고
    • A microfabricated fluorescence-activated cell sorter
    • A. Y. Fu et al., A microfabricated fluorescence-activated cell sorter Nat. Biotechnol. 1999 17 11 1109 1111
    • (1999) Nat. Biotechnol. , vol.17 , Issue.11 , pp. 1109-1111
    • Fu, A.Y.1
  • 43
    • 4744345465 scopus 로고    scopus 로고
    • A microfabricated device for subcellular organelle sorting
    • H. Lu et al., A microfabricated device for subcellular organelle sorting Anal. Chem. 2004 76 19 5705 5712
    • (2004) Anal. Chem. , vol.76 , Issue.19 , pp. 5705-5712
    • Lu, H.1
  • 44
    • 42949083256 scopus 로고    scopus 로고
    • An equilibrium method for continuous-flow cell sorting using dielectrophoresis
    • M. D. Vahey J. Voldman An Equilibrium Method for Continuous-Flow Cell Sorting Using Dielectrophoresis Anal. Chem. 2008 80 9 3135 3143
    • (2008) Anal. Chem. , vol.80 , Issue.9 , pp. 3135-3143
    • Vahey, M.D.1    Voldman, J.2
  • 45
    • 42149135990 scopus 로고    scopus 로고
    • Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells
    • M. Chabert J. L. Viovy Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells Proc. Natl. Acad. Sci. U. S. A. 2008 105 9 3191
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , Issue.9 , pp. 3191
    • Chabert, M.1    Viovy, J.L.2
  • 46
    • 27644555545 scopus 로고    scopus 로고
    • Marker-specific sorting of rare cells using dielectrophoresis
    • X. Hu et al., Marker-specific sorting of rare cells using dielectrophoresis Proc. Natl. Acad. Sci. U. S. A. 2005 102 44 15757 15761
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , Issue.44 , pp. 15757-15761
    • Hu, X.1
  • 47
    • 62549099947 scopus 로고    scopus 로고
    • Micromagnetic selection of aptamers in microfluidic channels
    • X. Lou et al., Micromagnetic selection of aptamers in microfluidic channels Proc. Natl. Acad. Sci. U. S. A. 2009 106 9 2989 2994
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , Issue.9 , pp. 2989-2994
    • Lou, X.1
  • 49
    • 0029438538 scopus 로고
    • Laser killing of cells in Caenorhabditis elegans
    • C. I. Bargmann L. Avery Laser killing of cells in Caenorhabditis elegans Methods Cell Biol. 1995 48 225 50
    • (1995) Methods Cell Biol. , vol.48 , pp. 225-250
    • Bargmann, C.I.1    Avery, L.2
  • 50
    • 61849100059 scopus 로고    scopus 로고
    • High-throughput in vivo genetic and drug screening using femtosecond laser nano-surgery, and microfluidics
    • C. Rohde et al., High-throughput in vivo genetic and drug screening using femtosecond laser nano-surgery, and microfluidics Conf Proc IEEE Eng. Med. Biol. Soc. 2008 2008 2642
    • (2008) Conf Proc IEEE Eng. Med. Biol. Soc. , vol.2008 , pp. 2642
    • Rohde, C.1
  • 51
    • 34248998179 scopus 로고    scopus 로고
    • A micromanipulation system with dynamic force-feedback for automatic batch microinjection
    • Z. Lu et al., A micromanipulation system with dynamic force-feedback for automatic batch microinjection J. Micromech. Microeng. 2007 17 2 314 321
    • (2007) J. Micromech. Microeng. , vol.17 , Issue.2 , pp. 314-321
    • Lu, Z.1
  • 52
    • 33645757831 scopus 로고    scopus 로고
    • Microoptical characterization of piezoelectric vibratory microinjections in Drosophila embryos for genome-wide RNAi screen
    • X. J. Zhang et al., Microoptical characterization of piezoelectric vibratory microinjections in Drosophila embryos for genome-wide RNAi screen J. Microelectromech. Syst. 2006 15 2 277 286
    • (2006) J. Microelectromech. Syst. , vol.15 , Issue.2 , pp. 277-286
    • Zhang, X.J.1
  • 53
    • 68149166794 scopus 로고    scopus 로고
    • Transport of live yeast and zebrafish embryo on a droplet ("digital") microfluidic platform
    • S. U. Son R. L. Garrell Transport of live yeast and zebrafish embryo on a droplet ("digital") microfluidic platform Lab Chip 2009 9 16 2398 2401
    • (2009) Lab Chip , vol.9 , Issue.16 , pp. 2398-2401
    • Son, S.U.1    Garrell, R.L.2


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