Identification and characterization of a novel l-amino acid ligase from Photorhabdus luminescens subsp. laumondii TT01

Journal of Bioscience and Bioengineering

Volumn 110, Issue 1, 2010, Pages 39-41

  Kino, Kuniki ^a   Noguchi, Atsushi ^a   Arai, Toshinobu ^a   Yagasaki, Makoto ^b  

^a WASEDA UNIVERSITY   (Japan)

^b Kyowa Hakko Bio Co   (Japan)

Author keywords

Dipeptide; Enzymatic peptide synthesis; In silico screening; l Amino acid ligase; Photorhabdus luminescens

Indexed keywords

DI-PEPTIDES; DIPEPTIDE; IN-SILICO; IN-SILICO SCREENING; L-AMINO ACID LIGASE; L-AMINO ACIDS; NEW MEMBERS; PEPTIDE SYNTHESIS; SUBSTRATE SPECIFICITY;

ORGANIC ACIDS; PEPTIDES; SYNTHESIS (CHEMICAL);

AMINO ACIDS;

AMINO ACID LIGASE; ASPARAGINE; BACTERIAL PROTEIN; LIGASE; PLU1440 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE SYNTHESIS; PHOTORHABDUS; PHOTORHABDUS LAUMONDII; PROTEIN FUNCTION;

AMINO ACIDS; ASPARAGINE; DIPEPTIDES; LIGASES; PHOTORHABDUS; SUBSTRATE SPECIFICITY;

PHOTORHABDUS LUMINESCENS; PHOTORHABDUS LUMINESCENS SUBSP. LAUMONDII;

EID: 77953104355     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2009.12.004     Document Type: Article

References (14)

1. Yagasaki M., and Hashimoto S. Synthesis and application of dipeptides; current status and perspectives. Appl. Microbiol. Biotechnol. 81 (2008) 13-22
2. Murzin A.G. Structural classification of proteins: new superfamilies. Curr. Opin. Struct. Biol. 6 (1996) 386-394
3. Tabata K., Ikeda H., and Hashimoto S. ywfE in Bacillus subtilis code for a novel enzyme, l-amino acid ligase. J. Bacteriol. 187 (2005) 5195-5202
4. Tabata K., and Hashimoto S. Fermentative production of l-alanyl-l-glutamine by a metabolically engineered Escherichia coli strain expressing l-amino acid α-ligase. Appl. Environ. Microbiol. 73 (2007) 6378-6385
5. Kino K., Nakazawa Y., and Yagasaki M. Dipeptide synthesis by l-amino acid ligase from Ralstonia solanacearum. Biochem. Biophys. Res. Commun. 371 (2008) 536-540
6. Kino K., Noguchi A., and Yagasaki M. A novel l-amino acid ligase from Bacillus licheniformis. J. Biosci. Bioeng. 106 (2008) 313-315
7. Arai T., and Kino K. A novel l-amino acid ligase is encoded by a gene in the phaseolotoxin biosynthetic gene cluster from Pseudomonas syringae pv. phaseolicola 1448A. Biosci. Biotechnol. Biochem. 72 (2008) 3048-3050
8. Kino K., Kotanaka Y., Arai T., and Yagasaki M. A novel l-amino acid ligase from Bacillus subtilis NBRC3134, a microorganism producing peptide-antibiotic rhizocticin. Biosci. Biotechnol. Biochem. 73 (2009) 901-907
9. Inaoka T., Takahashi K., Ohnishi-Kameyama M., Yoshida M., and Ochi K. Guanine nucleotides guanosine 5′-diphosphate 3′-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis. J. Biol. Chem. 278 (2003) 2169-2176
10. Rapp C., Jung G., Kugler M., and Loeffler W. Rhizocticins-new phosphono-oligopeptides with antifungal activity. Liebigs Ann. Chem. 1988 (1988) 655-661
11. Bender C.L., Alarcón-Chaidez F., and Gross D.C. Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthetases. Microbiol. Mol. Biol. Rev. 63 (1999) 266-292
12. Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A., Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.F., Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Médigue C., Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M., Glaser P., Boemare N., Danchin A., and Kunst F. The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens. Nat. Biotechnol. 21 (2003) 1307-1313
13. Sambrook J., and Russell W.D. Molecular cloning: a laboratory manual. 3rd ed (2001), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
14. Arai T., and Kino K. A cyanophycin synthetase from Thermosynechococcus elongatus BP-1 catalyzes primer-independent cyanophycin synthesis. Appl. Microbiol. Biotechnol. 81 (2008) 69-78