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Volumn 5, Issue 6, 2010, Pages 930-940

Fragment-based lead discovery: Screening and optimizing fragments for thermolysin inhibition

(9) Englert, Lisa a Silber, Katrin a Steuber, Holger a,b Brass, Sascha a Over, Björn a Gerber, Hans Dieter a Heine, Andreas a Diederich, Wibke E a Klebe, Gerhard a

a PHILIPPS UNIVERSITY MARBURG (Germany)

b UNIVERSITY OF LÜBECK (Germany)

Author keywords

Drug discovery; Fragment based design; Inhibitors; Medicinal chemistry; Virtual screening; X ray diffraction

Indexed keywords

PROTEINASE INHIBITOR; THERMOLYSIN;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEINASE INHIBITION;

ASPIRIN; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DATABASES, PROTEIN; DRUG DESIGN; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; SOFTWARE; THERMOLYSIN;

EID: 77953092035 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201000084 Document Type: Article

Times cited : (22)

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