New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation

Bone

Volumn 46, Issue 6, 2010, Pages 1533-1545

  Gluhak Heinrich, J ^a   Guo, D ^b   Yang, W ^a   Harris, M A ^a   Lichtler, A ^c   Kream, B ^c   Zhang, J ^d   Feng, J Q ^e   Smith, L C ^e   Dechow, P ^e   Harris, S E ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF DENTISTRY   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e BAYLOR COLLEGE OF DENTISTRY   (United States)

Author keywords

Alveolar bone; Dentin; Enamel; Periodontal ligament; Teeth

Indexed keywords

AMELOBLASTIN; AMELOGENIN; BONE MORPHOGENETIC PROTEIN 4; COLLAGEN TYPE 1; DENTIN MATRIX PROTEIN 1; OSTEOCALCIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX3; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR OSTERIX; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOLOGY; DENTIN; ENAMEL; GENE DELETION; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; ODONTOBLAST; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TOOTH; TOOTH DEVELOPMENT; TOOTH PULP; X RAY ANALYSIS;

AMELOBLASTS; AMELOGENIN; ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; DENTAL ENAMEL; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; ODONTOBLASTS; OSTEOBLASTS; TOOTH; TRANSCRIPTION FACTORS;

EID: 77953020793     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.02.024     Document Type: Article

References (31)

1. Vainio S., Karavanova I., Jowett A., Thesleff I. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 1993, 75:45-58.
2. Maas R., Bei M. The genetic control of early tooth development. Crit Rev Oral Biol Med 1997, 8:4-39.
3. Bei M., Kratochwil K., Maas R.L. BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development. Development 2000, 127:4711-4718.
4. Zhang Z., Song Y., Zhang X., Tang J., Chen J., Chen Y. Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev 2003, 120:1469-1479.
5. Mina M., Kollar E.J. The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch Oral Biol 1987, 32:123-127.
6. Ohazama A., Tucker A., Sharpe P.T. Organized tooth-specific cellular differentiation stimulated by BMP4. J Dent Res 2005, 84:603-606.
7. Liu W., Selever J., Murali D., Sun X., Brugger S.M., Ma L., et al. Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol 2005, 283:282-293.
8. Winnier G., Blessing M., Labosky P.A., Hogan B.L. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 1995, 9:2105-2116.
9. Gluhak-Heinrich J., Guo D., Yang W., Martinez L., Harris M., Kulessa H., et al. Role of Bone Morphogenetic Protein 4 (BMP-4) in tooth development. Bone Morphogenetic Proteins: From Local to Systemic Therapeutics 2008, 199:211. Birkhauser Verlag, Basel, Switzeland.
10. Kulessa H., Hogan B.L. Generation of a loxP flanked bmp4loxP-lacZ allele marked by conditional lacZ expression. Genesis: the Journal of Genetics & Development 2002, 32:66-68.
11. Liu F., Woitge H.W., Braut A., Kronenberg M.S., Lichtler A.C., Mina M., et al. Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues. Int J Dev Biol 2004, 48:645-653.
12. Gluhak-Heinrich J., Yang W., Harris M., Harris S.E. Quantitative in situ hybridization with enhanced sensitivity in soft, bone and tooth tissue using digoxigenin tagged RNA probes. Biochem Med 2008, 18:59-80.
13. Ye L., MacDougall M., Zhang S., Xie Y., Zhang J., Li Z., et al. Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem 2004, 279:19141-19148.
14. D'Souza R.N., Aberg T., Gaikwad J.S., Cavender A., Owen M., Karsenty G., et al. Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice. Development 1999, 126:2911-2920.
15. Li H., Marijanovic I., Kronenberg M.S., Erceg I., Stover M.L., Velonis D., et al. Expression and function of Dlx genes in the osteoblast lineage. Dev Biol 2008, 316:458-470.
16. Kapadia H., Xie Y., Zhou X., Crombrugghe B.D., D'Souza R.N., Feng J.Q. Osterix is critical for odontogenesis and condyle formation. 87 General session of the IADR, Miami FL 2009.
17. Yagi K., Tsuji K., Nifuji A., Shinomiya K., Nakashima K., DeCrombrugghe B., et al. Bone morphogenetic protein-2 enhances Osterix gene expression in chondrocytes. J Cell Biochem 2003, 88:1077-1083.
18. Massague J. Integration of Smad and MAPK pathways: a link and a linker revisited. Genes Dev 2003, 17:2993-2997.
19. Dong J., Amor D., Aldred M.J., Gu T., Escamilla M., MacDougall M. DLX3 mutation associated with autosomal dominant amelogenesis imperfecta with taurodontism. Am J Med Genet A 2005, 133A:138-141.
20. Lee S.K., Lee Z.H., Lee S.J., Ahn B.D., Kim Y.J., Lee S.H., et al. DLX3 mutation in a new family and its phenotypic variations. J Dent Res 2008, 87:354-357.
21. Wright J.T., Hong S.P., Simmons D., Daly B., Uebelhart D., Luder H.U. DLX3 c.561_562delCT mutation causes attenuated phenotype of tricho-dento-osseous syndrome. Am J Med Genet A 2008, 146:343-349.
22. Lee S.K., Lee K.E., Jeon D., Lee G., Lee H., Shin C.U., et al. A novel mutation in the DSPP gene associated with dentinogenesis imperfecta type II. J Dent Res 2009, 88:51-55.
23. Haruyama N., Sreenath T.L., Suzuki S., Yao X., Wang Z., Wang Y., et al. Genetic evidence for key roles of decorin and biglycan in dentin mineralization. Matrix Biol 2009, 28:129-136.
24. Chae Y.M., Heo S.H., Kim J.Y., Lee J.M., Ryoo H.M., Cho J.Y. Upregulation of smpd3 via BMP2 stimulation and Runx2. BMB Rep 2009, 42:86-90.
25. Feng J.Q., Zhang J., Tan X., Lu Y., Guo D., Harris S.E. Identification of cis-DNA regions controlling Bmp4 expression during tooth morphogenesis in vivo. J Dent Res 2002, 81:6-10.
26. Tadic T., Erceg I., Stover M.L., Rowe D.W., Lichtler A.C. Dlx5 induces expression of COL1A1 promoter contained in a retrovirus vector. Croat Med J 2001, 42:436-439.
27. Chen S, Gluhak-Heinrich J, Wang YH, Wu YM, Chuang HH, Chen L, et al., in press. Runx2, Osx and Dspp expression in tooth development. J Dent Res 2009;88(10):904-9.
28. Bei M., Maas R. FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development 1998, 125:4325-4333.
29. Veis A. Amelogenin gene splice products: potential signaling molecules. Cell Mol Life Sci 2003, 60:38-55.
30. Iacob S, Veis A. Identification of temporal and spatial expression patterns of Amelogenin isoforms during mouse molar development. Eur J Oral Sci 2006;114 Suppl 1: 194-200; discussion 201-2.
31. Lu Y., Xie Y., Zhang S., Dusevich V., Bonewald L.F., Feng J.Q. DMP1-targeted Cre expression in odontoblasts and osteocytes. J Dent Res 2007, 86:320-325.