New technologies for the detection of circulating tumour cells

British Medical Bulletin

Volumn 94, Issue 1, 2010, Pages 49-64

  Gerges, Noha ^a   Rak, Janusz ^a   Jabado, Nada ^a  

^a MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

Carcinoma; CTC; Detection

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CD45 ANTIGEN; CD61 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CYTOKERATIN; CYTOKERATIN 19; EPITHELIAL CELL ADHESION MOLECULE; EPITHELIAL MEMBRANE ANTIGEN; FICOLL; MICRORNA; NUCLEIC ACID; TRASTUZUMAB;

BONE MARROW BIOPSY; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER GROWTH; CANCER HORMONE THERAPY; CANCER MORTALITY; CANCER PATIENT; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CELL SELECTION; CELL SEPARATION; CELL SIZE; CELL STRUCTURE; CELL SURVIVAL; CIRCULATING TUMOR CELL; CLINICAL TRIAL; DENSITY GRADIENT CENTRIFUGATION; DIGESTIVE SYSTEM CANCER; DISSEMINATED CANCER; ENRICHMENT CULTURE; ENZYME LINKED IMMUNOSPOT ASSAY; EPITHELIAL IMMUNOSPOT; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FIBER OPTICS; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOMAGNETIC SELECTION; LASER SCANNING CYTOMETRY; MAGNETISM; METASTASIS; MICROFLUIDIC ANALYSIS; MICROMETASTASIS; MULTIPHOTON INTRAVITAL FLOW CYTOMETRY; PRIMARY TUMOR; PRIORITY JOURNAL; PROGNOSIS; QUALITATIVE ANALYSIS; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TUMOR CELL; CARCINOMA; IMMUNOHISTOCHEMISTRY; MOLECULAR DIAGNOSIS; PATHOLOGY; PROCEDURES; SECONDARY; TUMOR EMBOLISM;

CARCINOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR DIAGNOSTIC TECHNIQUES; NEOPLASTIC CELLS, CIRCULATING;

EID: 77953006348     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldq011     Document Type: Review

References (47)

1. Weiss L. Metastasis of cancer: a conceptual history from antiquity to the 1990s. Cancer Metastasis Rev 2000;19:193-383.
2. Fidler IJ. Critical determinants of cancer metastasis: rationale for therapy. Cancer Chemother Pharmacol 1999;43(Suppl.):S3-S10.
3. Husemann Y, Geigl JB, Schubert F et al. Systemic spread is an early step in breast cancer. Cancer Cell 2008;13:58-68.
4. Meng S, Tripathy D, Frenkel EP et al. Circulating tumor cells in patients with breast cancer dormancy. Clin Cancer Res 2004;10:8152-8162
5. Ghossein RA, Scher HI, Gerald WL et al. Detection of circulating tumor cells in patients with localized and metastatic prostatic carcinoma: clinical implications. J Clin Oncol 1995;13:1195-1200
6. Coman DR, de LR, Mcc UM. Studies on the mechanisms of metastasis; the distribution of tumors in various organs in relation to the distribution of arterial emboli. Cancer Res 1951;11:648-651
7. Zieglschmid V, Hollmann C, Gutierrez B et al. Combination of immunomagnetic enrichment with multiplex RT-PCR analysis for the detection of disseminated tumor cells. Anticancer Res 2005;25:1803-1810
8. Braun S, Vogl FD, Naume B et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med 2005;353:793-802. (Pubitemid 41215488)
9. Braun S, Naume B. Circulating and disseminated tumor cells. J Clin Oncol 2005;23:1623-1626
10. Singletary SE, Greene FL, Sobin LH. Classification of isolated tumor cells: clarification of the 6th edition of the American Joint Committee on Cancer Staging Manual. Cancer 2003;98:2740-2741
11. Singletary SE, Greene FL. Revision of breast cancer staging: the 6th edition of the TNM Classification. Semin Surg Oncol 2003;21:53-59
12. Hermanek P, Sobin LH, Wittekind C. How to improve the present TNM staging system. Cancer 1999;86:2189-2191
13. Harris L, Fritsche H, Mennel R et al. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol 2007;25:5287-5312 (Pubitemid 350232263)
14. Slade MJ, Coombes RC. The clinical significance of disseminated tumor cells in breast cancer. Nat Clin Pract Oncol 2007;4:30-41.
15. Pierga JY, Bonneton C, Vincent-Salomon A et al. Clinical significance of immunocytochemi-cal detection of tumor cells using digital microscopy in peripheral blood and bone marrow of breast cancer patients. Clin Cancer Res 2004;10:1392-1400 (Pubitemid 38365234)
16. Cristofanilli M. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. Semin Oncol 2006;33:S9-S14.
17. Ignatiadis M, Xenidis N, Perraki M et al. Different prognostic value of cytokeratin-19 mRNA positive circulating tumor cells according to estrogen receptor and HER2 status in early-stage breast cancer. J Clin Oncol 2007;25:5194-5202
18. Ignatiadis M, Perraki M, Apostolaki S et al. Molecular detection and prognostic value of circulating cytokeratin-19 messenger RNA-positive and HER2 messenger RNA-positive cells in the peripheral blood of women with early-stage breast cancer. Clin Breast Cancer 2007;7:883-889
19. Paterlini-Brechot P, Benali NL. Circulating tumor cells (CTC) detection: clinical impact and future directions. Cancer Lett 2007;253:180-204.
20. Mocellin S, Keilholz U, Rossi CR et al. Circulating tumor cells: the 'leukemic phase' of solid cancers. Trends Mol Med 2006;12:130-139
21. Jacob K, Sollier C, Jabado N. Circulating tumor cells: detection, molecular profiling and future prospects. Expert Rev Proteomics 2007;4:741-756
22. Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003;3:453-458
23. Rak J, Milsom C, Yu J. Vascular determinants of cancer stem cell dormancy\do age and coagulation system play a role? Apmis 2008;116:660-676
24. Braun S, Pantel K, Muller P et al. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med 2000;342:525-533
25. Schmidt H, DeAngelis G, Eltze E et al. Asynchronous growth of prostate cancer is reflected by circulating tumor cells delivered from distinct, even small foci, harboring loss of heterozyg-osity of the PTEN gene. Cancer Res 2006;66:8959-8965
26. Solakoglu O, Maierhofer C, Lahr G et al. Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors. Proc Natl Acad Sci USA 2002;99:2246-2251
27. Mostert B, Sleijfer S, Foekens JA et al. Circulating tumor cells (CTCs): detection methods and their clinical relevance in breast cancer. Cancer Treat Rev 2009;35:463-474
28. Vona G, Sabile A, Louha M et al. Isolation by size of epithelial tumor cells: a new method for the immunomorphological and molecular characterization of circulatingtumor cells. Am J Pathol 2000;156:57-63.
29. Naume B, Borgen E, Tossvik S et al. Detection of isolated tumor cells in peripheral blood and in BM: evaluation of a new enrichment method. Cytotherapy 2004;6:244-252
30. Krivacic RT, Ladanyi A, Curry DN et al. A rare-cell detector for cancer. Proc Natl Acad Sci USA 2004;101:10501-10504
31. He W, Wang H, Hartmann LC et al. In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry. Proc Natl Acad Sci USA 2007;104:11760-11765
32. Riethdorf S, Fritsche H, Muller V et al. Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system. Clin Cancer Res 2007;13:920-928 (Pubitemid 46340368)
33. Pierga JY, Bidard FC, Mathiot C et al. Circulating tumor cell detection predicts early meta-static relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial. Clin Cancer Res 2008;14:7004-7010
34. Bidard FC, Saliba AE, Saias L et al. Circulating tumor cells and breast cancer: detection techniques and clinical results. Bull Cancer 2009;96:73-86.
35. Nagrath S, Sequist LV, Maheswaran S et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 2007;450:1235-1239
36. Alix-Panabieres C, Riethdorf S, Pantel K. Circulating tumor cells and bone marrow microme-tastasis. Clin Cancer Res 2008;14:5013-5021
37. Kojima T, Hashimoto Y, Watanabe Y et al. A simple biological imaging system for detecting viable human circulating tumor cells. J Clin Invest 2009;119:3172-3181
38. Bertolini F, Shaked Y, Mancuso P et al. The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer 2006;6:835-845
39. Gerhard M, Juhl H, Kalthoff H et al. Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 1994;12:725-729
40. Kaplan JC, Kahn A, Chelly J. Illegitimate transcription: its use in the study of inherited disease. Hum Mutat 1992;1:357-360
41. Schoenfeld A, Luqmani Y, Smith D et al. Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction. Cancer Res 1994;54:2986-2990
42. Johnson PW, Burchill SA, Selby PJ. The molecular detection of circulating tumour cells. Br J Cancer 1995;72:268-276
43. Ghossein RA, Bhattacharya S, Rosai J. Molecular detection of micrometastases and circulating tumor cells in solid tumors. Clin Cancer Res 1999;5:1950-1960
44. Ghossein RA, Carusone L, Bhattacharya S. Review: polymerase chain reaction detection of micrometastases and circulating tumor cells: application to melanoma, prostate, and thyroid carcinomas. Diagn Mol Pathol 1999;8:165-175
45. Ghossein RA, Osman I, Bhattacharya S et al. Detection of prostatic specific membrane antigen messenger RNA using immunobead reverse transcriptase polymerase chain reaction. Diagn Mol Pathol 1999;8:59-65.
46. Pantel K, Alix-Panabieres C, Riethdorf S. Cancer micrometastases. Nat Rev Clin Oncol 2009;6:339-351
47. Bertolini F, Mancuso P, Braidotti P et al. The multiple personality disorder phenotype(s) of circulating endothelial cells in cancer. Biochim Biophys Acta 2009.