Floppy eyelid syndrome as a subset of lax eyelid conditions: Relationships and clinical relevance (an ASOPRS thesis)

Ophthalmic Plastic and Reconstructive Surgery

Volumn 26, Issue 3, 2010, Pages 195-204

  Fowler, Amy M ^a   Dutton, Jonathan J ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CONJUNCTIVITIS; DISEASE ASSOCIATION; ECTROPION; EYELID DISEASE; EYELID FLACCIDITY; FEMALE; FLOPPY EYELID SYNDROME; HUMAN; KERATOCONUS; MALE; MEIBOMIAN GLAND; OBESITY; PREVALENCE; PRIORITY JOURNAL; PTOSIS; ROSACEA; SLEEP APNEA SYNDROME; SMOKING; SUN EXPOSURE;

ADULT; AGED; AGED, 80 AND OVER; EYELID DISEASES; EYELIDS; FEMALE; HUMANS; INFANT; KERATOCONUS; MALE; MIDDLE AGED; OBESITY; PREVALENCE; RETROSPECTIVE STUDIES; SEX FACTORS; SLEEP APNEA SYNDROMES; SYNDROME;

EID: 77953003728     PISSN: 07409303     EISSN: None     Source Type: Journal    
DOI: 10.1097/IOP.0b013e3181b9e37e     Document Type: Article

References (78)

1. Culbertson WW, Ostler HB. The floppy eyelid syndrome. Am J Ophthalmol 1981;92:568-75.
2. Apostolopoulos M, Papaspirou A, Damanakis A, et al. Bilateral optic neuropathy associated with voluntary globe luxation and floppy eyelid syndrome. Arch Ophthalmol 2004;122:1555-6.
3. Boulton JE, Sullivan TJ. Floppy eyelid syndrome and mental retardation. Ophthalmology 2000;107:1989-91.
4. Easterbrook M. Floppy eyelid syndrome. Can J Ophthalmol 1985;20:264-5.
5. Müllner-Eidenböck A, Moser E, Klebermass N, et al. Ocular features of the congenital cataracts facial dysmorphism neuropathy syndrome. Ophthalmology 2004;111:1415-23.
6. Segev F, Héon E, Cole WG, et al. Structural abnormalities of the cornea and lid resulting from collagen V mutations. Invest Ophthalmol Vis Sci 2006;47:565-73.
7. Lee WJ, Kim JC, Shyn KH. Clinical evaluation of corneal diseases associated with floppy eyelid syndrome. Korean J Ophthalmol 1996;10:116-21.
8. Goldberg R, Seiff S, McFarland J, et al. Floppy eyelid syndrome and blepharochalasis. Am J Ophthalmol 1986;102:376-81.
9. Gerner EW, Hughes SM. Floppy eyelid with hyperglycinemia. Am J Ophthalmol 1984;98:614-6.
10. Karesh JW, Nirankari VS, Hameroff SB. Eyelid imbrication. An unrecognized cause of chronic ocular irritation. Ophthalmology 1993;100:883-9.
11. van den Bosch WA, Lemij HG. The lax eyelid syndrome. Br J Ophthalmol 1994;78:666-70.
12. Burkat CN, Lemke BN. Acquired lax eyelid syndrome: an unrecognized cause of the chronically irritated eye. Ophthal Plast Reconstr Surg 2005;21:52-8.
13. Shah-Desai S, Sandy C, Collin R. Lax eyelid syndrome or 'progeria' of eyelid tissues. Orbit 2004;23:3-12.
14. Woog JJ. Obstructive sleep apnea and the floppy eyelid syndrome. Am J Ophthalmol 1990;110:314-5.
15. McNab AA. The eye and sleep. Clin Experiment Ophthalmol 2005;33:117-25.
16. McNab AA. Floppy eyelid syndrome and obstructive sleep apnea. Ophthal Plast Reconstr Surg 1997;13:98-114.
17. Abdal H, Pizzimenti JJ, Purvis CC. The eye in sleep apnea syndrome. Sleep Med 2006;7:107-15.
18. Diniz CM, Tzelikis PF, Rodrigues Júnior A, et al. [Unilateral keratoconus associated with continual eye rubbing due to nasolacrimal obstruction-case report]. Arq Bras Oftalmol 2005;68:122-5.
19. Ioannidis AS, Speedwell L, Nischal KK. Unilateral keratoconus in a child with chronic and persistent eye rubbing. Am J Ophthalmol 2005;139:356-7.
20. Jafri B, Lichter H, Stulting RD. Asymmetric keratoconus attributed to eye rubbing. Cornea 2004;23:560-4.
21. Krachmer JH. Eye rubbing can cause keratoconus. Cornea 2004;23:539-40.
22. Lindsay RG, Bruce AS, Gutteridge IF. Keratoconus associated with continual eye rubbing due to punctal agenesis. Cornea 2000;19:567-9.
23. McMonnies CW, Boneham GC. Keratoconus, allergy, itch, eyerubbing and hand-dominance. Clin Exp Optom 2003;86:376-84.
24. Weed KH, MacEwen CJ, Giles T, et al. The Dundee University Scottish Keratoconus study: demographics, corneal signs, associated diseases, and eye rubbing. Eye 2008;22:534-41.
25. Parunovic A. Floppy eyelid syndrome. Br J Ophthalmol 1983;67:264-6.
26. Donnenfeld ED, Perry HD, Gibralter RP, et al. Keratoconus associated with floppy eyelid syndrome. Ophthalmology 1991;98:1674-8.
27. Culbertson WW, Tseng SC. Corneal disorders in floppy eyelid syndrome. Cornea 1994;13:33-42.
28. Huber-Spitzy V, Grabner G, Stur M. [Syndrome of the flaccid eyelid (floppy eyelid syndrome]. Klin Monatsbl Augenheilkd 1984;185:289-91 (in German).
29. Negris R. Floppy eyelid syndrome associated with keratoconus. J Am Optom Assoc 1992;63:316-9.
30. Brown MD, Potter JW. Floppy eyelid syndrome: a case report and clinical review. J Am Optom Assoc 1992;63:309-14.
31. Center for Disease Control and Prevention. BMI-Body Mass Index. Atlanta, GA: Center for Disease Control and Prevention, 2007.
32. Bouchard CS. Lateral tarsorrhaphy for a noncompliant patient with floppy eyelid syndrome. Am J Ophthalmol 1992;114:367-9.
33. Gross RH, Mannis MJ. Floppy eyelid syndrome in a child with chronic unilateral conjunctivitis. Am J Ophthalmol 1997;124:109-10.
34. Langford JD, Linberg JV. A new physical finding in floppy eyelid syndrome. Ophthalmology 1998;105:165-9.
35. Lemke BN, Sires BS, Dortzbach RK. A tarsal strip-periosteal flap technique for lateral canthal fixation. Ophthalmic Surg Lasers 1999;30:232-6.
36. Netland PA, Sugrue SP, Albert DM, Shore JW. Histopathologic features of the floppy eyelid syndrome. Involvement of tarsal elastin. Ophthalmology 1994;101:174-81.
37. Reifler DM. Floppy eyelids and crack eye syndrome. Ophthalmology 1993;100:975.
38. Samaha AN, Farah NT, Maaluf R. Floppy eyelid syndrome in a child with vernal catarrh. J Pediatr Ophthalmol Strabismus 1999;36:216-8.
39. Eiferman RA, Gossman MD, O'Neill K, Douglas CH. Floppy eyelid syndrome in a child. Am J Ophthalmol 1990;109:356-7.
40. Moore MB, Harrington J, McCulley JP. Floppy eyelid syndrome. Management including surgery. Ophthalmology 1986;93:184-8.
41. Rapoza PA, Quinn TC, Terry AC, et al. A systematic approach to the diagnosis and treatment of chronic conjunctivitis. Am J Ophthalmol 1990;109:138-42.
42. Bilenchi R, Poggiali S, Pisani C, et al. Floppy eyelid syndrome associated with obstructive sleep apnea. Br J Dermatol 2004;151:706.
43. Karger RA, White WA, Park WC, et al. Prevalence of floppy eyelid syndrome in obstructive sleep apnea-hypopnea syndrome. Ophthalmology 2006;113:1669-74.
44. Liu DT, Di Pascuale MA, Sawai J, et al. Tear film dynamics in floppy eyelid syndrome. Invest Ophthalmol Vis Sci 2005;46:1188-94.
45. McNab AA. Reversal of floppy eyelid syndrome with treatment of obstructive sleep apnoea. Clin Experiment Ophthalmol 2000;28:125-6.
46. Periman LM, Sires BS. Floppy eyelid syndrome: a modified surgical technique. Ophthal Plast Reconstr Surg 2002;18:370-2.
47. Rossiter JD, Ellingham R, Hakin KN, Twomey JM. Corneal melt and perforation secondary to floppy eyelid syndrome in the presence of rheumatoid arthritis. Br J Ophthalmol 2002;86:483.
48. Taban M, Taban M, Perry JD. Plasma leptin levels in patients with floppy eyelid syndrome. Ophthal Plast Reconstr Surg 2006;22:375-7.
49. Valenzuela AA, Sullivan TJ. Medial upper eyelid shortening to correct medial eyelid laxity in floppy eyelid syndrome: a new surgical approach. Ophthal Plast Reconstr Surg 2005;21:259-63.
50. Alexandrakis G, Tse DT, Chang WJ. Spontaneous globe luxation associated with floppy eyelid syndrome and shallow orbits. Arch Ophthalmol 1999;117:138-9.
51. Da Prá A, Brunzini M, Croxatto JO, Nano H. [Floppy eyelid syndrome. 5 cases]. Ophtalmologie 1989;3:314 (in French).
52. Gonnering RS, Sonneland PR. Meibomian gland dysfunction in floppy eyelid syndrome. Ophthal Plast Reconstr Surg 1987;3:99-103.
53. Mojon DS, Goldblum D, Fleischhauer J, et al. Eyelid, conjunctival, and corneal findings in sleep apnea syndrome. Ophthalmology 1999;106:1182-5.
54. Paciuc M, Mier ME. A woman with the floppy eyelid syndrome. Am J Ophthalmol 1982;93:255-6.
55. Schlötzer-Schrehardt U, Stojkovic M, Hofmann-Rummelt C, et al. The Pathogenesis of floppy eyelid syndrome: involvement of matrix metalloproteinases in elastic fiber degradation. Ophthalmology 2005;112:694-704. (Pubitemid 41108873)
56. Scholten E, Marck KW, Grond AJ. Surgical correction of floppy eyelids. Br J Plast Surg 1998;51:264-6.
57. Reyniers R, Paridaens D. Spontaneous globe luxation and floppy eyelid syndrome in a patient with Hashimoto's disease. Eye 2007;21:303-4.
58. Diller R, Sant S. A case report and review of filamentary keratitis. Optometry 2005;76:30-6.
59. Dufek MA, Shechtman DL. Floppy eyelid syndrome: a diagnostic dilemma. J Am Optom Assoc 1999;70:450-4.
60. Dutton JJ. Surgical management of floppy eyelid syndrome. Am J Ophthalmol 1985;99:557-60.
61. Fleishman JA, Hoffman RO. An unusual case of floppy eyelid syndrome. Ann Ophthalmol 1988;20:468-9.
62. Goldberg RA, Coden DJ, Hornblass A, Mitchell JP. Floppy eyelid syndrome associated with marked lower eyelid ectropion. Am J Ophthalmol 1989;108:610-2.
63. Parunovi 72:634-5.
64. Schwartz LK, Gelender H, Forster RK. Chronic conjunctivitis associated with 'floppy eyelids.' Arch Ophthalmol 1983;101:1884-8.
65. Rao LG, Bhandary SV, Devi AR, Gangadharan S. Floppy eyelid syndrome in an infant. Indian J Ophthalmol 2006;54:217-8.
66. Perry HD, Donnenfeld ED. Dry eye diagnosis and management in 2004. Curr Opin Ophthalmol 2004;15:299-304.
67. Young T, Palta M, Dempsey J, et al. The occurrence of sleepdisordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-5.
68. Valencia-Flores M, Orea A, Castaño VA, et al. Prevalence of sleep apnea and electrocardiographic disturbances in morbidly obese patients. Obes Res 2000;8:262-9.
69. Punjabi NM, Sorkin JD, Katzel LI, et al. Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am J Respir Crit Care Med 2002;165:677-82.
70. Javaheri S. A mechanism of central sleep apnea in patients with heart failure. N Engl J Med 1999;341:949-54.
71. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000;342:1378-84. (Pubitemid 30262394)
72. Suratt PM, Findley LJ. Driving with sleep apnea. N Engl J Med 1999;340:881-3.
73. Yaggi HK, Concato J, Kernan WN, et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 2005;353:2034-41.
74. Grunaüer-Kloevekorn C, Duncker GI. [Keratoconus: epidemiology, risk factors and diagnosis]. Klin Monatsbl Augenheilkd 2006;223:493-502 (in German).
75. Arocker-Mettinger E, Haddad R, Konrad K, Steinkogler FJ. [Floppy eyelid syndrome: light and electron microscopy studies]. Klin Monatsbl Augenheilkd 1986;188:596-8 (in German).
76. Lindsey M, Wedin K, Brown MD, et al. Matrix-dependent mechanism of neutrophil-mediated release and activation of matrix metalloproteinase 9 in myocardial ischemia/reperfusion. Circulation 2001;103:2181-7.
77. Park HY, Kwon HM, Lim HJ, et al. Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metaloproteinases in vivo and in vitro. Exp Mol Med 2001;33:95-102.
78. Mulholland B, Tuft SJ, Khaw PT. Matrix metalloproteinase distribution during early corneal wound healing. Eye 2005;19:584-8.