Neuroradiology of chemo therapeutic neurotoxicity in children

Neuroradiology Journal

Volumn 23, Issue 2, 2010, Pages 183-190

  Rossi, Andrea ^a   Morana, G ^a   Gandolfo, C ^a   Severino, M ^a  

^a G GASLINI INSTITUTE   (Italy)

Author keywords

Chemotherapy; Neurotoxicity

Indexed keywords

ASPARAGINASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTARABINE; HYDROCORTISONE; METHOTREXATE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BLEEDING TENDENCY; BONE MARROW TRANSPLANTATION; BRAIN HEMORRHAGE; BRAIN INFARCTION; CANCER SURVIVAL; CENTRAL NERVOUS SYSTEM; CHILD; CONVULSION; DEMYELINATION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG INDUCED HEADACHE; EARLY DIAGNOSIS; GRAFT VERSUS HOST REACTION; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HUMAN; HYPERCOAGULABILITY; LEUKOENCEPHALOPATHY; NEURORADIOLOGY; NEUROTOXICITY; OVERALL SURVIVAL; PERIPHERAL NEUROPATHY; POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME; PRESCHOOL CHILD; SCHOOL CHILD; SPINAL CORD DISEASE; VEIN THROMBOSIS;

EID: 77952977968     PISSN: 19714009     EISSN: None     Source Type: Journal    
DOI: 10.1177/197140091002300206     Document Type: Article

References (32)

1. Rossi A, Biancheri R et Al: Neuroradiology of pediatric hemolymphoproliferative disease. Riv Neuroradiol 16: 221-250, 2003.
2. Ginsberg LE, Leeds NE: Neuroradiology of leukemia. AJR Am J Roentgenol 165: 525-534, 1995.
3. Ball WS Jr, Prenger EC, Ballard ET: Neurotoxicity of radio/chemotherapy in children: pathologic and MR correlation. AJNR Am J Neuroradiol 13: 761-776, 1992.
4. Chen CY, Zimmerman RA et Al: Childhood leukemia: central nervous system abnormalities during and after treatment. AJNR Am J Neuroradiol 17: 295-310, 1996.
5. Asato R, Akiyama Y et Al: Nuclear magnetic resonance abnormalities of the cerebral white matter in children with acute lymphoblastic leukemia and malignant lymphoma during and after central nervous system prophylactic treatment with intrathecal methotrexate. Cancer 70: 1997-2004, 1992.
6. Ebner F, Ranner G et Al: MR findings in methotrexate-induced CNS abnormalities. Am J Neuroradiol 10: 959-964, 1989. (Pubitemid 19219643)
7. von der Weid NX, de Crousaz H et Al: Acute fatal myeloencephalopathy after combined intrathecal chemotherapy in a child with acute lymphoblastic leukemia. Med Pediatr Oncol 19: 192-198, 1991.
8. Stone JA, Castillo M, Mukherji SK: Leukoencephalopathy complicating an Ommaya reservoir and chemotherapy. Neuroradiology 41: 134-136, 1999.
9. Priest JR, Ramsay NK et Al: A syndrome of thrombosis and hemorrhage complicating L-asparaginase therapy for childhood acute lymphoblastic leukemia. J Pediatr 100: 984-989, 1982.
10. Rathi B, Azad RK et Al: L-asparaginase-induced reversible posterior leukoencephalopathy syndrome in a child with acute lymphoblastic leukemia. Pediatr Neurosurg 37: 203-205, 2002.
11. Vaughn DJ, Jarvik JG et Al: High-dose cytarabine neurotoxicity: MR findings during the acute phase. Am J Neuroradiol 14: 1014-1016, 1993.
12. Vazquez E, Lucaya J et Al: Neuroimaging in pediatric leukemia and lymphoma: differential diagnosis. Radiographics 22: 1411-1428, 2002.
13. Faraci M, Lanino E et Al: Severe neurologic complications after hematopoietic stem cell transplantation in children. Neurology 59: 1895-1904, 2002.
14. Provenzale JM, Graham ML: Reversible leukoencephalopathy associated with graft-versus-host disease: MR findings. AJNR Am J Neuroradiol 17: 1290-1294, 1996.
15. Padovan CS, Yousry TA et Al: Neurological and neuroradiological findings in long-term survivors of allogeneic bone marrow transplantation. Ann Neurol 43: 627-633, 1998.
16. Ferrara JL, Deeg HJ: Graft-versus-host disease. N Engl J Med 324: 667-674, 1991.
17. Zimmer WE, Hourihane JM et Al: The effect of human leukocyte antigen disparity on cyclosporine neurotoxicity after allogeneic bone marrow transplantation. Am J Neuroradiol 19: 601-608, 1998.
18. Beausang-Linder M, Bill A: Cerebral circulation in acute arterial hypertension - protective effects of sympathetic nervous activity. Acta Physiol Scand 111: 193-199, 1981. (Pubitemid 11134146)
19. Hinchey J, Chaves C: A reversible posterior leukoencephalopathy syndrome. N Engl J Med 334: 494-500, 1996. (Pubitemid 26067737)
20. Coley SC, Porter DA et Al: Quantitative MR diffusion mapping and cyclosporine-induced neurotoxicity. Am J Neuroradiol 20: 1507-1510, 1999.
21. Gleeson JG, duPlessis AJ et Al: Cyclosporin A acute encephalopathy and seizure syndrome in childhood: clinical features and risk of seizure recurrence. J Child Neurol 13: 336-344, 1998.
22. Pavlakis SG, Frank Y, Chusid R: Hypertensive encephalopathy, reversible occipitoparietal encephalopathy, or reversible posterior leukoencephalopathy: three names for an old syndrome. J Child Neurol 14: 277-281 1999 (Pubitemid 29239182)
23. Pace MT, Slovis TL et Al: Cyclosporin A toxicity: MRI appearance of the brain. Pediatr Radiol 25: 180-183, 1995.
24. Schwartz RB, Bravo SM et Al: Cyclosporine neurotoxicity and its relationship to hypertensive encephalopathy: CT and MR findings in 16 cases. Am J Roentgenol 165: 627-631, 1995.
25. Truwit CL, Denaro CP et Al: MR imaging of reversible cyclosporin A-induced neurotoxicity. Am J Neuroradiol 12: 651-659, 1991.
26. Dillon WP, Rowley H: The reversible posterior cerebral edema syndrome. Am J Neuroradiol 19: 591, 1998. (Pubitemid 30422779)
27. Debaere C, Stadnik T et Al: Diffusion-weighted MRI in cyclosporin A neurotoxicity for the classification of cerebral edema. Eur Radiol 9: 1916-1918, 1999.
28. Dowling C, Bollen AW et Al: Preoperative proton MR spectroscopic imaging of brain tumors: correlation with histopathologic analysis of resection specimens. Am J Neuroradiol 22: 604-612, 2001.
29. Schaefer PW, Buonanno FS et Al: Diffusion-weighted imaging discriminates between cytotoxic and vasogenic edema in a patient with eclampsia. Stroke 28: 1082-1085, 1997.
30. Morana G, Faraci M, Rossi A: Cyclosporine (CS) neurotoxicity in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT): conventional MR and diffusion-weighted imaging findings. Abstracts 34th Annual meeting of the European Society of Neuroradiology. Athens (Greece), 17-20/9/2009. Neuroradiology 51 (Suppl 1): S76, 2009.
31. Antunes NL, Small TN et Al: Posterior leukoencephalopathy syndrome may not be reversible. Pediatr Neurol 20: 241-243, 1999.
32. Teksam M, Casey SO et Al: Subarachnoid hemorrhage associated with cyclosporine A neurotoxicity in a bonemarrow transplant recipient. Neuroradiology 43: 242-245, 2001.