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Volumn 65 A, Issue 6, 2010, Pages 577-579

Rapamycin joins the aging fray

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; SIGNAL PEPTIDE;

EID: 77952977261     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glq049     Document Type: Review
Times cited : (6)

References (9)
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    • The role of mTOR signaling in controlling mammalian lifespan: What a fungicide teaches us about longevity
    • Sharp Z, Strong R. The role of mTOR signaling in controlling mammalian lifespan: what a fungicide teaches us about longevity. J Gerontol A Biol Sci Med Sci. 2010;65(6):580-589.
    • (2010) J Gerontol A Biol Sci Med Sci. , vol.65 , Issue.6 , pp. 580-589
    • Sharp, Z.1    Strong, R.2
  • 2
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    • Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009;460(7253):392- 395.
    • (2009) Nature. , vol.460 , Issue.7253 , pp. 392-395
    • Harrison, D.E.1    Strong, R.2    Sharp, Z.D.3
  • 3
    • 56749182467 scopus 로고    scopus 로고
    • Design of aging intervention studies: The niA interventions testing program
    • Nadon NL, Strong R, Miller RA, et al. design of aging intervention studies: the niA interventions testing program. Age. 2008;30(4):187-199.
    • (2008) Age. , vol.30 , Issue.4 , pp. 187-199
    • Nadon, N.L.1    Strong, R.2    Miller, R.A.3
  • 4
    • 52449114485 scopus 로고    scopus 로고
    • Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice
    • Strong R, Miller RA, Astle CM, et al. nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell. 2008;7(5):641-650.
    • (2008) Aging Cell , vol.7 , Issue.5 , pp. 641-650
    • Strong, R.1    Miller, R.A.2    Astle, C.M.3
  • 5
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov. 2006;5(6):493-506.
    • (2006) Nat Rev Drug Discov. , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 6
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
    • Pearson KJ, Baur JA, Lewis KN, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008;8(2):157-168.
    • (2008) Cell Metab. , vol.8 , Issue.2 , pp. 157-168
    • Pearson, K.J.1    Baur, J.A.2    Lewis, K.N.3
  • 7
    • 70350454798 scopus 로고    scopus 로고
    • Molecular interplay between mTOR, Ab and tau: Effects on cognitive impairments
    • Caccamo A, Majumder S, Richardson A, Strong R, Oddo S. Molecular interplay between mTOR, Ab and tau: effects on cognitive impairments. J Biol Chem. 2010;284(40):27416-27424.
    • (2010) J Biol Chem. , vol.284 , Issue.40 , pp. 27416-27424
    • Caccamo, A.1    Majumder, S.2    Richardson, A.3    Strong, R.4    Oddo, S.5
  • 8
    • 77956305343 scopus 로고    scopus 로고
    • Et al. inhibition of mTOR by rapamycin abolishes cognitive defcits and reduces amyloid-b levels in a mouse model of Alzheimer's disease
    • Spilman P, Podlutskaya N, Hart MJ, et al. inhibition of mTOR by rapamycin abolishes cognitive defcits and reduces amyloid-b levels in a mouse model of Alzheimer's disease. PLoS One. 2010; 5(4):e9979.
    • (2010) PLoS One. , vol.5 , Issue.4
    • Spilman, P.1    Podlutskaya, N.2    Hart, M.J.3
  • 9
    • 75749127850 scopus 로고    scopus 로고
    • Greene LA. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease
    • Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, greene LA. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. J Neurosci. 2010;30(3): 1166-1175.
    • (2010) J Neurosci. , vol.30 , Issue.3 , pp. 1166-1175
    • Malagelada, C.1    Jin, Z.H.2    Jackson-Lewis, V.3    Przedborski, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.