Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 6, 2010, Pages 1143-1150

  Cristofaro, Brunella ^a   Stone, Oliver A ^b   Caporali, Andrea ^a   Dawbarn, David ^c   Ieronimakis, Nicholas ^d   Reyes, Morayma ^d   Madeddu, Paolo ^a   Bates, David O ^b   Emanueli, Costanza ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b Microvascular Research Laboratories   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Angiogenesis; Endothelial cells; Limb ischemia; Neurotrophin 3; PI3K Akt eNOS

Indexed keywords

ADENOVIRUS VECTOR; MATRIGEL; NEUROTROPHIN 3; NEUROTROPHIN 3 RECEPTOR; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT PROTEIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE MODEL; DRUG MECHANISM; ENDOTHELIUM CELL; GENE OVEREXPRESSION; GENE TRANSFER; HEART DEVELOPMENT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMB ISCHEMIA; MALE; MESENTERY BLOOD FLOW; MOUSE; MUSCLE CAPILLARY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; TRANSGENIC RAT; VIRAL GENE DELIVERY SYSTEM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANGIOGENIC PROTEINS; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENE THERAPY; HINDLIMB; HUMANS; ISCHEMIA; MALE; MESENTERY; MICE; MUSCLE, SKELETAL; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE GROWTH FACTORS; NEUROTROPHIN 3; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTOR, TRKC; RECOMBINANT PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 77952885832     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.205468     Document Type: Article

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