Ultrasound-Guided Sclerotherapy of the Great Saphenous Vein with 1% vs. 3% Polidocanol Foam: A Multicentre Double-Blind Randomised Trial with 3-Year Follow-Up

European Journal of Vascular and Endovascular Surgery

Volumn 39, Issue 6, 2010, Pages 779-786

  Blaise, S ^a   Bosson, J L ^a   Diamand, J M ^b  

^a GRENOBLE UNIVERSITY HOSPITAL   (France)

^b NONE

Author keywords

Great saphenous vein; Polidocanol; Superficial venous incompetence; Ultrasound guided foam sclerotherapy

Indexed keywords

POLIDOCANOL;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; ECHOGRAPHY; FEMALE; FOLLOW UP; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PAIN; PIGMENTATION; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SAPHENOUS VEIN; SCLEROTHERAPY; SIDE EFFECT; SKIN INFLAMMATION; SUPERFICIAL THROMBOPHLEBITIS; THROMBOEMBOLISM; VEIN INSUFFICIENCY; VEIN THROMBOSIS; VENOUS REFLUX;

DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; POLYETHYLENE GLYCOLS; PROSPECTIVE STUDIES; SAPHENOUS VEIN; SCLEROSING SOLUTIONS; SCLEROTHERAPY; TIME FACTORS; TISSUE ADHESIVES; TREATMENT OUTCOME; ULTRASONOGRAPHY, DOPPLER, COLOR; VENOUS INSUFFICIENCY;

EID: 77952880251     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2010.01.022     Document Type: Article

References (21)

1. Hamel-Desnos C., Ouvry P., Benigni J.-P., Boitelle G., Schadeck M., Desnos P., et al. Comparison of 1% and 3% polidocanol foam in ultrasound guided sclerotherapy of the great saphenous vein: a randomized double-blind trial with 2 year-follow-up. "The 3/1 study". Eur J Vasc Endovasc Surg 34 (2007) 723-729
2. Rutherford R.B., Padberg F.T., Comerota A.J., Kistner R.L., Meissner M.H., and Moneta G.L. Venous severity scoring: an adjunct to venous outcome assessment. J Vasc Surg 31 (2000) 1307-1312
3. Launois R., Reboul-Marty J., and Henry B. Construction and validation of a quality of life questionnaire in chronic lower limb venous insufficiency (CIVIQ). Qual Life Res 5 (1996) 539-554
4. Rabe E., Otto J., Schliephake D., and Pannier F. Efficacy and safety of great saphenous vein sclerotherapy using standardized polidocanol foam (ESAF): a randomized controlled multicentre clinical trial. Eur J Vasc Endovasc Surg 35 (2007) 238-245
5. Alos J., Carreno P., Lopez J.A., Estadella B., Serrat-Prat M., and Marinel-Lo J. Efficacy and safety of sclerotherapy polidocanol foam: a controlled clinical trial. Eur J Vasc Endovasc Surg 31 (2006) 101-107
6. Hamel-Desnos C., Desnos P., Wollmann J.C., Ouvry P., Mako S., and Allaert F.A. Evaluation of the efficacy of polidocanol in the form of foam compared with liquid form in sclerotherapy of the greater saphenous vein: initial results. Dermatol Surg 29 12 (2003) 1170-1175
7. Ouvry P., Allaert F.A., Desnos P., and Hamel-Desnos C. Efficacy of polidocanol foam versus liquid in sclerotherapy of the great saphenous vein: a multicentre randomised controlled trial with a 2 year follow-up. Eur J Vasc Endovasc Surg 36 (2008) 366-370
8. Jia X., Mowatt G., Burr J.M., Cassar K., Cook J., and Fraser C. Systematic review of foam sclerotherapy for varicose veins. Br J Surg 94 (2007) 925-936
9. ® polidocanol microfoam compared with surgery or sclerotherapy in the management of varicose veins in the presence of trunk vein incompetence: European randomized controlled trial. Phlebology 21 (2006) 180-190
10. Rao J., and Goldman M.P. Stability of foam in sclerotherapy: differences between sodium tetradecyl sulfate and polidocanol and the type of connector used in the double-syringe system technique. Dermatol Surg 31 1 (2005 Jan) 19-22
11. Hamel-Desnos C., and Desnos P. L'écho-sclérothérapie à la mousse en 2004. Technique de la ponction-injection directe. Phlébologie 57 (2004) 289-300
12. Barrett J.M., Allen B., Ockelford A., and Goldman M.P. Microfoam ultrasound-guided sclerotherapy treatment for varicose veins in a subgroup with diameters at the junction of 10 mm or greater compared with a subgroup of less than 10 mm. Dermato Surg 30 (2004) 1386-1390
13. Hamel-Desnos C., Allaert F.A., Benigni J.-P., Boitelle G., Chleir F., Ouvry P., et al. Etude 3/1.Mousse de Polidocanol 3% versus 1% dans la grande veine saphène: premiers résultats. Phlébologie 58 (2005) 165-173
14. Breu F.X., Guggenbichler S., and Wollmann J.C. Duplex ultrasound and efficacy criteria in foam sclerotherapy from the 2nd European consensus meeting on foam sclerotherapy 2006, Tegernsee, Germany. VASA 37 (2008) 90-95
15. Breu F.X., and Guggenbichler S. European consensus meeting on foam sclerotherapy, April, 4-6, 2003, Tegernsee, Germany. Dermatol Surg 30 (2004) 709-717
16. Gachet G., and Spini L. Référentiel sur le traitement endovasculaire des varices par injections échoguidées de mousses fibrosantes: le consensus d'experts de Grenoble. Phlébologie 61 2 (2008) 196-206
17. Ceulen R.P.M., Bullens-Goessens Y.I.J.M., Pi-Van De Venne S.J.A., Nelemans P.J., Veraart J.C.J.M., and Sommer A. Outcomes and side effects of duplex-guided sclerotherapy in the treatment of great saphenous veins with 1% versus 3% polidocanol foam: results of a randomized controlled trial with 1-Year follow-up. Dermatol Surg 33 (2007) 276-281
18. Barrett J.M., Allen B., Ockelford A., and Goldman M.P. Microfoam ultrasound-guided sclerotherapy of varicose veins in 100 legs. Dermatol Surg 30 (2004) 6-12
19. Myers K.A., and Jolley D. Factors affecting the risk of deep venous occlusion after ultrasound-guided sclerotherapy for varicose veins. Eur J Vasc Endovasc Surg 36 5 (2008) 602-605
20. Guex J.J., Allaert F.A., Gillet J.L., and Chleir F. Immediate and midterm complications of sclerotherapy: report of a prospective multicenter registry of 12,173 sclerotherapy sessions. Dermatol Surg 31 2 (2005) 123-128
21. Myers K.A., Jolley D., Clough A., and Kirwan J. Outcome of ultrasound-guided sclerotherapy for varicose veins: medium-term results assessed by ultrasound surveillance. Eur J Vasc Endovasc Surg 33 1 (2007) 116-121