Comparison of 1% and 3% Polidocanol Foam in Ultrasound Guided Sclerotherapy of the Great Saphenous Vein: A Randomised, Double-Blind Trial with 2 Year-Follow-up. "The 3/1 Study"

European Journal of Vascular and Endovascular Surgery

Volumn 34, Issue 6, 2007, Pages 723-729

  Hamel Desnos, C ^a   Ouvry, P ^a   Benigni, J P ^a   Boitelle, G ^a   Schadeck, M ^a   Desnos, P ^a   Allaert, F A ^b  

^a Societe Francaise de Ceramique   (France)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Foam sclerosant; Foam sclerotherapy; Polidocanol; Sclerotherapy; Ultrasound guided sclerotherapy; Varicose veins

Indexed keywords

POLIDOCANOL;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DOUBLE BLIND PROCEDURE; ECHOGRAPHY; FEMALE; FOAM; FOLLOW UP; HUMAN; INTERVENTIONAL RADIOLOGY; MACHINE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAPHENOUS VEIN; SCLEROTHERAPY; STANDARDIZATION; SYRINGE; VEIN OCCLUSION; VENOUS REFLUX;

ADULT; DOSAGE FORMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; POLYETHYLENE GLYCOLS; PROSPECTIVE STUDIES; RECURRENCE; SAPHENOUS VEIN; SCLEROSING SOLUTIONS; SCLEROTHERAPY; ULTRASONOGRAPHY, INTERVENTIONAL; VARICOSE VEINS;

EID: 35848953860     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2007.07.014     Document Type: Article

References (29)

1. Traitement des varices des membres inférieurs. Rapport de l'Agence Nationale d'Accréditation et d'Evaluation en Santé. Service Evaluation en santé publique - Evaluation technologique Juin 2004.
2. Jia X., Mowatt G., Burr J.M., Cassar K., Cook J., and Fraser C. Systematic review of foam sclerotherapy for varicose veins. Br J Surg 94 (2007) 925-936
3. Schadeck M. Doppler et échotomographie dans la sclérose des veines saphènes. Phlébologie 39 (1986) 697-716
4. Knight R.M., Vin F., and Zygmunt J.A. Ultrasonic guidance of injection into the superficial venous system. In: Davy A., and Stemmer R. (Eds). Phlébologie (1989), John Libbey Eurotext 339-341
5. Cabrera Garrido J.R. Elargissement des limites de la sclérothérapie: nouveaux produits sclérosants. Phlébologie 50 (1997) 181-188
6. Monfreux A. Traitement sclérosant des troncs saphèniens et leurs collatérales de gros calibre par la méthode MUS. Phlébologie 50 (1997) 351-353
7. Hamel-Desnos C., Desnos P., Wollmann J.C., Ouvry P., Mako S., and Allaert F.A. Evaluation of the efficacy of polidocanol in the form of foam compared with liquid form in sclerotherapy of the greater saphenous vein: initial results. Dermatol Surg 29 (2003) 1170-1175
8. Ouvry P., and Hamel-Desnos C. Evaluation de l'efficacité du Lauromacrogol sous forme mousse versus forme liquide dans la sclérothérapie de la grande veine saphène. Résultats après 2 ans de suivi (2004), Société Française de Phlébologie Réunion du 4 décembre 2004 - Abstract
9. Yamaki T., Nozaki M., and Iwasaka S. Comparative study of duplex-guided foam sclerotherapy and duplex-guided liquid sclerotherapy for the treatment of superficial venous insufficiency. Dermatol Surg 30 5 (2004) 718-722
10. Breu F.X., and Guggenbichler S. European consensus meeting on foam sclerotherapy, April 4-6, 2003, Tegernsee, Germany. Dermatol Surg 30 5 (2004 May) 709-717
11. Wollmann J.C. Schaum - zwischen Vergangenheit und Zukunft. 8. Bonner Venentage 15-16. Feb. Vasomed 16 1 (2002) 34-35
12. Hamel-Desnos C., Allaert F.A., Benigni J.P., Boitelle G., Chleir F., Ouvry P., et al. Pour la Société Française de Phlébologie. ≪Etude 3/1. Mousse de Polidocanol 3% versus 1% dans la grande veine saphène. Premiers résultats≫. Phlébologie 58 2 (2005) 165-173
13. Hamel-Desnos C., and Desnos P. L'écho-sclérothérapie à la mousse en 2004. Technique de la ponction-injection directe. Phlébologie 57 3 (2004) 289-300
14. Coleridge Smith P. Chronic venous disease treated by ultrasound guided foam sclerotherapy. Eur J Vasc Endovasc Surg 32 (2006) 577-583
15. Cavezzi A., Frullini A., Ricci S., and Tessari L. Treatment of varicose veins by foam sclerotherapy: two clinical series. Phlebology 17 (2002) 13-18
16. Cabrera J., Cabrera Jr. J., and Garcia-Olmedo M.A. Treatment of varicose great saphenous veins with sclerosant in micro-foam form: long term outcomes. Phlebology 15 (2000) 19-23
17. Frullini A., and Cavezzi A. Echosclérose par mousse de tétradécyl-sulfate de sodium et de polidocanol: deux années d'expérience. Phlébologie 53 4 (2000) 431-435
18. ® polidocanol microfoam compared with surgery or sclerotherapy in the management of varicose veins in the presence of trunk vein incompetence: European randomized controlled trial. Phlebology 21 4 (2006) 180-190
19. Barett J.M., Allen B., Ockelford A., and Goldman M. Microfoam ultrasound-guided sclerotherapy of varicose veins in 100 legs. Dermatol Surg 30 1 (January 2004) 6-12
20. Hamel-Desnos C., Ramelet A.A., and Guias B. Efficacité des mousses de sclérosants: synthèse des principaux essais cliniques publiés. Angéiologie 56 2 (2004) 39-44
21. Bergan J., Pascarella L., and Mekenas L. Venous disorders: treatment with sclerosant foam. J Cardiovasc Surg 47 1 (2006 Feb) 9-18
22. Bountouroglou D.G., Azzam M., Kakkos S.K., Pathmarajah M., Young P., and Geroulakos G. Ultrasound-guided foam sclerotherapy combined with sapheno-femoral ligation compared to surgical treatment of varicose veins: early results of a randomised controlled trial. Eur J Vasc Endovasc Surg 31 (2006) 93-100
23. Guex J.J., Allaert F.A., Gillet J.L., and Chleir F. Immediate and midterm complications of sclerotherapy: report of a prospective multi-center. Registry of 12,173 sclerotherapy sessions. Dermatol Surg 31 (2005) 123-128
24. Hobbs J.T. Surgery or sclerotherapy for varicose veins: 10-year results of a random trial. In: Tesi M., and Dormandy J.A. (Eds). Superficial and deep venous diseases of the lower limbs (Sept 1984), Panminerva Medica, Turin 243-248
25. Tessari L. Nouvelle technique d'obtention de la scléro-mousse. Phlébologie 53 1 (2000) 129
26. Rao J., and Goldman M. Stability of foam in sclerotherapy: differences between sodium tetradecyl sulfate and polidocanol and the type of connector used in the double-syringe system technique. Dermatol Surg 31 1 (2005) 19-22
27. Ceulen R.P., Bullens-Goessens Y.I., Pi-Van De Venne S.J., Nelemans P.J., Veraart J.J., and Sommer A. Outcomes and side effects of duplex-guided sclerotherapy in the treatment of great saphenous veins with 1% versus 3% polidocanol foam: results of a randomized controlled trial with 1-year follow-up. Dermatol Surg 33 (2007) 276-281
28. Myers K., Jolley D., Clough A., and Kirwan J. Outcome of ultrasound-guided sclerotherapy for varicose veins: medium-term results assessed by ultrasound surveillance. Eur J Vasc Endovasc Surg 33 (2007) 116-121
29. Frullini A. Foam sclerotherapy: a review. Phlebolymphology 40 (2003) 125-129