Randomized clinical trial of intravenous soybean oil alone versus soybean oil plus fish oil emulsion after gastrointestinal cancer surgery

British Journal of Surgery

Volumn 97, Issue 6, 2010, Pages 804-809

  Jiang, Z M ^a   Wilmore, D W ^b   Wang, X R ^a   Wei, J M ^c   Zhang, Z T ^d   Gu, Z Y ^e   Wang, S ^f   Han, S M ^g   Jiang, H ^h   Yu, K ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b Medical School   (United States)

^c BEIJING HOSPITAL   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

^e 301 General Hospital   (China)

^f PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^g PEKING UNION MEDICAL COLLEGE   (China)

^h SICHUAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FISH OIL; INTERLEUKIN 6; SOYBEAN OIL; TUMOR NECROSIS FACTOR ALPHA;

AGED; ANALYSIS OF VARIANCE; ARTICLE; BODY MASS; BODY WEIGHT; CD4 CD8 RATIO; CLINICAL TRIAL; COLON TUMOR; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST BENEFIT ANALYSIS; ECONOMICS; EMULSION; FEMALE; GASTROINTESTINAL TUMOR; HUMAN; IMMUNOLOGY; INTRAVENOUS DRUG ADMINISTRATION; LENGTH OF STAY; MALE; METABOLISM; MIDDLE AGED; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFECTION; SURGICAL INFECTION; URINARY TRACT INFECTION;

AGED; ANALYSIS OF VARIANCE; BODY MASS INDEX; BODY WEIGHT; CD4-CD8 RATIO; COLONIC NEOPLASMS; COST-BENEFIT ANALYSIS; EMULSIONS; FEMALE; FISH OILS; GASTROINTESTINAL NEOPLASMS; HUMANS; INFUSIONS, INTRAVENOUS; INTERLEUKIN-6; LENGTH OF STAY; MALE; MIDDLE AGED; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; RESPIRATORY TRACT INFECTIONS; SOYBEAN OIL; SURGICAL WOUND INFECTION; TUMOR NECROSIS FACTOR-ALPHA; URINARY TRACT INFECTIONS;

EID: 77952784152     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.6999     Document Type: Article

References (22)

1. Carpentier YA, Dupont IE. Advances in intravenous lipid emulsions. World J Surg 2000; 24: 1493-1497.
2. Adolph M. Lipid emulsions in parenteral nutrition. Ann Nutr Metah 1999; 43: 1-13.
3. Mayer K, Fegbeutel C, Hattar K, Sibelius U, Krämer HJ, Heuer KU et al. Omega-3 vs. omega-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation. Intensive Care Med 2003; 29: 1472-1481. (Pubitemid 37153591)
4. Heller AR, Rössel T, Gottschlich B, Tiebel O, Menschikowski M, Litz RJ et al. Omega-3 fatty acids improve liver and pancreas function in postoperative cancer patients. Int. J Cancer 2004; 111: 611-616. (Pubitemid 39045330)
5. Mayer K, Gokorsch S, Fegbeutel C, Hattar K, Rosseau S, Walmrath D et al. Parenteral nutrition with fish oil modulates cytokine response in patients with sepsis. Am J Respir Crit Care Med 2003; 167: 1321-1328. (Pubitemid 36609714)
6. Mayer K, Meyer S, Reinholz-Muhly M, Maus U, Merfels M, Lohmeyer J et al. Short-time infusion of fish oil-based lipid emulsions, approved for parenteral nutrition, reduces monocyte proinflammatory cytokine generation and adhesive interaction with endothelium, in humans. J Immunol 2003; 171:4837-4843. (Pubitemid 37310605)
7. Wichmann MW, Thul P, Czametzki HD, Morlion BJ, Kernen M, Jauch KW. Evaluation of clinical safety and beneficial effects of a fish oil containing lipid emulsion (Lipoplus, MLF541): data from, a prospective, randomized, multicenter trial. Crit Care Med 2007; 35: 700-706. (Pubitemid 46407781)
8. Jiang ZM, Gu ZY, Chen FL, Wang XR, Li ZJ, Xu Y et al. Arginine, omega-3 fatty acid-enriched enteral nutrition on postoperative gut permeability, immune functions and outcome: randomized, controlled, multicenter clinical trials for 120 patients. Acta Chinese Academy of Medical Sciences 2001;23:515-518.
9. Sakurai Y, Oh-oka Y, Kato S, Suzuki S, Hayakawa M, Masui T et al. Effects of long-term continuous use of immune-enhancing enteral formula on nutritional and immunologic status in non-surgical patients. Nutrition 2006; 22:713-721. (Pubitemid 43947496)
10. Kelbel I, Wagner F, Wiedeck-Suger H, Kelbel M, Weiss M, Schneider M et al. Effects of n-3 fatty acids on immune function: a double-blind, randomized trial of fish oil based infusion in post-operative patients. Clin Nutr 2002; (Suppl 1): 21.
11. Heller AR, Rössler S, Litz RJ, Stehr SN, Heller SC, Koch R, et al. Omega-3 fatty acids improve the diagnosis-related clinical outcome. Crit Care Med 2006; 34: 972-979.
12. Weiss G, Meyer F, Matthies B, Pross M, Koenig W, Lippert H. Imtnunomodulation by perioperative administration of n-3 fatty acids. Br J Nutr 2002; 87(Suppl 1): S89-S94.
13. Mayer K, Schaefer MB, Weeger W. Fish oil in the critically ill: from experimental, to clinical data. Curr Opin Clin. Nutr Metab Care 2006; 9: 140-148. (Pubitemid 44090038)
14. Cooper A, Gibbons L, Horan M, Little R, Rothwell NJ. Effect of dietary fish oil supplementation on fever and cytokine production in human volunteers. Clin Nutr 1993; 12:321-329.
15. Caughey GE, Mantzioris E, Gibson RA, Cleland LG, James MJ. The effects on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am. J Clin Nutr 1996; 63: 116-122.
16. Johansen N, Kondrup J, Plum LM, Bak L, Nørregaard P, Bunch E et al. Effect of nutritional support on clinical outcome in patients at nutritional risk. Clin Nutr 2004; 23: 539-550. (Pubitemid 39107033)
17. Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Am J Infect Control 1992; 20: 271-274.
18. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit. Care Med 1992; 20: 864-874.
19. Schauder P Röhn U, Schäfer G, Korff G, Schenk HD. Impact of fish oil enriched total parenteral nutrition on DNA synthesis, cytokine release and receptor expression by lymphocytes in the postoperative period. Br J Nutr 2002; 87(Suppl. 1): S 1.03-S110.
20. Heller AR, Koch T. Immunologische Bedeutung von Fett in der parenteralen Ernährung am Beispiel der n-3 Fettsäuren. Aktuel Ernaehr Med 2002; 27: 222-229.
21. Zhu J, Paul WE. CD4 T cells: fates, functions, and faults. Blood 2008; 112:1557-1569.
22. Ryan AM, Reynolds JV, Healy L, Byrne M, Moore J, Brannelly N et al. Enteral nutrition enriched with eicosapentaenoic acid (EPA) preserves lean body mass following esophageal cancer surgery: results of a double-blinded randomized controlled trial. Ann Surg 2009; 249:355-363.