The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity

Biochemical and Biophysical Research Communications

Volumn 396, Issue 2, 2010, Pages 323-328

  Yao, Wenming ^a,b   Peng, Yu ^b   Lin, Donghai ^b,c  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c XIAMEN UNIVERSITY   (China)

Author keywords

ARID; EMSA; Intrinsic fluorescence; JARID1B PLU 1; NMR; Protein DNA interaction

Indexed keywords

DNA; DOUBLE STRANDED DNA; HISTONE H3; JARID1B PROTEIN; N DEMETHYLASE; NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; DEMETHYLATION; DNA BINDING; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; SEQUENCE ALIGNMENT;

BINDING SITES; DNA; DNA MUTATIONAL ANALYSIS; HELA CELLS; HISTONE DEMETHYLASES; HUMANS; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEAR PROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT;

EID: 77952744704     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.04.091     Document Type: Article

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