Respiratory viruses in childhood asthma

Current Opinion in Allergy and Clinical Immunology

Volumn 7, Issue 1, 2007, Pages 91-95

  Papadopoulos, Nikolaos G ^a,b   Kalobatsou, Alexandra ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b Allergy Research Center   (Greece)

Author keywords

Asthma; Respiratory syncytial virus; Rhinovirus; Viral respiratory infections

Indexed keywords

BCG VACCINE; BETA INTERFERON; BUDESONIDE; CROMOGLYCATE DISODIUM; FLUTICASONE; FORMOTEROL; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 4; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MONTELUKAST; PLACEBO; PREDNISOLONE; SALMETEROL; VASCULOTROPIN; VIRUS RNA;

ALLERGIC ASTHMA; ASTHMA; BCG VACCINATION; BRONCHIOLITIS; BRONCHUS HYPERREACTIVITY; CHILD DEVELOPMENT; CHILDHOOD DISEASE; COMBINATION CHEMOTHERAPY; CORONAVIRUS; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE PREDISPOSITION; HUMAN; HUMAN METAPNEUMOVIRUS; HUMAN RHINOVIRUS; IMMUNE RESPONSE; INFANCY; MONOTHERAPY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REINFECTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFLAMMATION; REVIEW; TORQUETENO VIRUS; VIRUS INFECTION; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS STRAIN; WHEEZING;

ASTHMA; CHILD; HUMANS; RESPIRATORY TRACT INFECTIONS;

EID: 33846220147     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e328013d501     Document Type: Review

References (47)

1. Sigurs N, Gustafsson PM, Bjarnason R, et al. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med 2005; 171:137-141.
2. Stein RT, Sherrill D, Morgan WJ, et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999; 354:541-545.
3. Dakhama A, Park JW, Taube C, et al. The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production. J Immunol 2005; 175:1876-1883.
4. H2-like response. J Allergy Clin Immunol 2005; 116:805-811.
5. Legg JP, Hussain IR, Warner JA, et al. Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis. Am J Respir Crit Care Med 2003; 168:633-639.
6. Gern JE, Brooks GD, Meyer P, et al. Bidirectional interactions between viral respiratory illnesses and cytokine responses in the first year of life. J Allergy Clin Immunol 2006; 117:72-78.
7. Lemanske RF Jr, Jackson DJ, Gangnon RE, et al. Rhinovirus illnesses during infancy predict subsequent childhood wheezing. J Allergy Clin Immunol 2005; 116:571-577.
8. Li R, Yang X, Wang L, Liu E. Respiratory syncytial virus infection reversed antiasthma effect of neonatal Bacillus Calmette-Guerin vaccination in BALB/c mice. Pediatr Res 2006; 59:210-215.
9. Johnston SL, Pattemore PK, Sanderson G, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ 1995; 310:1225-1229.
10. Van den Hoogen BG, De Jong JC, Groen J, et al. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med 2001; 7:719-724.
11. Van der Hoek L, Pyrc K, Jebbink MF, et al. Identification of a new human coronavirus. Nat Med 2004; 10:368-373.
12. Woo PC, Lau SK, Chu CM, et al. Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol 2005; 79:884-895.
13. Allander T, Tammi MT, Eriksson M, et al. Cloning of a human parvovirus by molecular screening of respiratory tract samples. Proc Natl Acad Sci USA 2005; 102:12891-12896.
14. Pifferi M, Maggi F, Andreoli E, et al. Associations between nasal torquetenovirus load and spirometric indices in children with asthma. J Infect Dis 2005; 192:1141-1148.
15. Bosis S, Esposito S, Niesters HG, et al. Impact of human metapneumovirus in childhood: comparison with respiratory syncytial virus and influenza viruses. J Med Virol 2005; 75:101-104.
16. Wolf DG, Greenberg D, Kalkstein D, et al. Comparison of human metapneumovirus, respiratory syncytial virus and influenza A virus lower respiratory tract infections in hospitalized young children. Pediatr Infect Dis J 2006; 25:320-324.
17. Hamelin ME, Prince GA, Gomez AM, et al. Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice. J Infect Dis 2006; 193:1634-1642.
18. Kusel MM, De Klerk NH, Holt PG, et al. Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study. Pediatr Infect Dis J 2006; 25:680-686.
19. Johnston NW, Johnston SL, Duncan JM, et al. The September epidemic of asthma exacerbations in children: a search for etiology. J Allergy Clin Immunol 2005; 115:132-138.
20. Johnston NW, Johnston SL, Norman GR, et al. The September epidemic of asthma hospitalization: school children as disease vectors. J Allergy Clin Immunol 2006; 117:557-562. Epidemiological proof for the perceived children-to-parents transmission of viral infections at the beginning of the school year.
21. Murray CS, Poletti G, Kebadze T, et al. Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children. Thorax 2006; 61:376-382.
22. Xepapadaki P, Papadopoulos NG, Bossios A, et al. Duration of postviral airway hyperresponsiveness in children with asthma: effect of atopy. J Allergy Clin Immunol 2005; 116:299-304.
23. Papadopoulos NG, Bates PJ, Bardin PG, et al. Rhinoviruses infect the lower airways. J Infect Dis 2000; 181:1875-1884.
24. Papadopoulos NG, Papi A, Meyer J, et al. Rhinovirus infection up-regulates eotaxin and eotaxin-2 expression in bronchial epithelial cells. Clin Exp Allergy 2001; 31:1060-1066.
25. Mosser AG, Vrtis R, Burchell L, et al. Quantitative and qualitative analysis of rhinovirus infection in bronchial tissues. Am J Respir Crit Care Med 2005; 171:645-651.
26. Kling S, Donninger H, Williams Z, et al. Persistence of rhinovirus RNA after asthma exacerbation in children. Clin Exp Allergy 2005; 35:672-678.
27. Ghildyal R, Dagher H, Donninger H, et al. Rhinovirus infects primary human airway fibroblasts and induces a neutrophil chemokine and a permeability factor. J Med Virol 2005; 75:608-615.
28. De Silva D, Dagher H, Ghildyal R, et al. Vascular endothelial growth factor induction by rhinovirus infection. J Med Virol 2006; 78:666-672.
29. Lee CG, Yoon HJ, Zhu Z, et al. Respiratory syncytial virus stimulation of vascular endothelial cell growth factor/vascular permeability factor. Am J Respir Cell Mol Biol 2000; 23:662-669.
30. Psarras S, Volonaki E, Skevaki CL, et al. Vascular endothelial growth factormediated induction of angiogenesis by human rhinoviruses. J Allergy Clin Immunol 2006; 117:291-297.
31. Xatzipsalti M, Kyrana S, Tsolia M, et al. Rhinovirus viremia in children with respiratory infections. Am J Respir Crit Care Med 2005; 172:1037-1040.
32. Chen Y, Hamati E, Lee PK, et al. Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFN-dependent pathways. Am J Respir Cell Mol Biol 2006; 34:192-203. This study uses gene array analysis and documents the significance of the IFN pathway in the early stages of rhinovirus infection.
33. Wark PA, Johnston SL, Bucchieri F, et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 2005; 201:937-947.
34. Hall DJ, Bates ME, Guar L, et al. The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells. J Immunol 2005; 174:8056-8063.
35. Laza-Stanca V, Stanciu LA, Message SD, et al. Rhinovirus replication in human macrophages induces NF-kappaB-dependent tumor necrosis factor alpha production. J Virol 2006; 80:8248-8258.
36. Dumitru CA, Dreschers S, Gulbins E. Rhinoviral infections activate p38MAP-kinases via membrane rafts and RhoA. Cell Physiol Biochem 2006; 17:159-166.
37. Groskreutz DJ, Monick MM, Powers LS, et al. Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells. J Immunol 2006; 176:1733-1740.
38. Hewson CA, Jardine A, Edwards MR, et al. Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells. J Virol 2005; 79:12273-12279.
39. Grunberg K, Sharon RF, Sont JK, et al. Rhinovirus-induced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infection. Am J Respir Crit Care Med 2001; 164:1816-1822.
40. Edwards MR, Johnson MW, Johnston SL. Combination therapy: synergistic suppression of virus-induced chemokines in airway epithelial cells. Am J Respir Cell Mol Biol 2006; 34:616-624.
41. Volonaki E, Psarras S, Xepapadaki P, et al. Synergistic effects of fluticasone propionate and salmeterol on inhibiting rhinovirus-induced epithelial production of remodelling-associated growth factors. Clin Exp Allergy 2006; 36:1268-1273.
42. Singam R, Jena PK, Behera S, et al. Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice. Virol J 2006; 3:32.
43. O'Byrne PM, Bisgaard H, Godard PP, et al. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am J Respir Crit Care Med 2005; 171:129-136.
44. Bisgaard H, Hermansen MN, Loland L, et al. Intermittent inhaled corticosteroids in infants with episodic wheezing. N Engl J Med 2006; 354:1998-2005. This study shows the lack of effectiveness of corticosteroid in either symptoms or long-term progression of episodic wheezing in infancy.
45. Jartti T, Lehtinen P, Vanto T, et al. Evaluation of the efficacy of prednisolone in early wheezing induced by rhinovirus or respiratory syncytial virus. Pediatr Infect Dis J 2006; 25:482-488.
46. Kotaniemi-Syrjanen A, Reijonen TM, Korhonen K, Korppi M. Sodium chromoglycate therapy in wheezing infants: preliminary evidence of beneficial outcome at early school age. Pediatr Int 2005; 47:627-634.
47. Bisgaard H, Zielen S, Garcia-Garcia ML, et al. Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma. Am J Respir Crit Care Med 2005; 171:315-322.