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Volumn 149, Issue 6, 2010, Pages 879-889

Rapid recovery of lymphocyte subsets is not associated with protection from relapse of myelodysplastic syndromes and acute myeloid leukaemia after haematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab

Author keywords

Alemtuzumab; Dendritic cells; Haematopoietic stem cell transplantation; Lymphocytes; Malignant disease

Indexed keywords

ALEMTUZUMAB; BUSULFAN; CYCLOSPORIN; FLUDARABINE; PREDNISOLONE; PSORALEN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

EID: 77952693546     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08164.x     Document Type: Article
Times cited : (13)

References (39)
  • 2
    • 33744774989 scopus 로고    scopus 로고
    • Exploiting beneficial alloreactive T cells
    • Barber, L.D. Madrigal, J.A. (2006) Exploiting beneficial alloreactive T cells. Vox Sanguinis, 91, 20 27.
    • (2006) Vox Sanguinis , vol.91 , pp. 20-27
    • Barber, L.D.1    Madrigal, J.A.2
  • 7
    • 3142648903 scopus 로고    scopus 로고
    • Alemtuzumab (Campath-1H) in allogeneic stem cell transplantation: Where do we go from here?
    • Chakrabarti, S., Hale, G. Waldmann, H. (2004) Alemtuzumab (Campath-1H) in allogeneic stem cell transplantation: where do we go from here? Transplantation Proceedings, 36, 1225 1227.
    • (2004) Transplantation Proceedings , vol.36 , pp. 1225-1227
    • Chakrabarti, S.1    Hale, G.2    Waldmann, H.3
  • 9
    • 0033230960 scopus 로고    scopus 로고
    • Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: Full donor T-cell chimerism precedes alloimmune responses
    • Childs, R., Clave, E., Contentin, N., Jayasekera, D., Hensel, N., Leitman, S., Read, E.J., Carter, C., Bahceci, E., Young, N.S. Barrett, A.J. (1999) Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses. Blood, 94, 3234 3241.
    • (1999) Blood , vol.94 , pp. 3234-3241
    • Childs, R.1    Clave, E.2    Contentin, N.3    Jayasekera, D.4    Hensel, N.5    Leitman, S.6    Read, E.J.7    Carter, C.8    Bahceci, E.9    Young, N.S.10    Barrett, A.J.11
  • 12
    • 0141475940 scopus 로고    scopus 로고
    • Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation
    • Dey, B.R., McAfee, S., Colby, C., Sackstein, R., Saidman, S., Tarbell, N., Sachs, D.H., Sykes, M. Spitzer, T.R. (2003) Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biology of Blood and Marrow Transplantation, 9, 320 329.
    • (2003) Biology of Blood and Marrow Transplantation , vol.9 , pp. 320-329
    • Dey, B.R.1    McAfee, S.2    Colby, C.3    Sackstein, R.4    Saidman, S.5    Tarbell, N.6    Sachs, D.H.7    Sykes, M.8    Spitzer, T.R.9
  • 13
    • 4444283753 scopus 로고    scopus 로고
    • Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning
    • Ho, A.Y., Pagliuca, A., Kenyon, M., Parker, J.E., Mijovic, A., Devereux, S. Mufti, G.J. (2004) Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning. Blood, 104, 1616 1623.
    • (2004) Blood , vol.104 , pp. 1616-1623
    • Ho, A.Y.1    Pagliuca, A.2    Kenyon, M.3    Parker, J.E.4    Mijovic, A.5    Devereux, S.6    Mufti, G.J.7
  • 16
    • 0036530011 scopus 로고    scopus 로고
    • Campath-1G causes rapid depletion of circulating host dendritic cells (DCs) before allogeneic transplantation but does not delay donor DC reconstitution
    • Klangsinsirikul, P., Carter, G.I., Byrne, J.L., Hale, G. Russell, N.H. (2002) Campath-1G causes rapid depletion of circulating host dendritic cells (DCs) before allogeneic transplantation but does not delay donor DC reconstitution. Blood, 99, 2586 2591.
    • (2002) Blood , vol.99 , pp. 2586-2591
    • Klangsinsirikul, P.1    Carter, G.I.2    Byrne, J.L.3    Hale, G.4    Russell, N.H.5
  • 17
    • 0029100438 scopus 로고
    • Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients
    • European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia
    • Kolb, H.J., Schattenberg, A., Goldman, J.M., Hertenstein, B., Jacobsen, N., Arcese, W., Ljungman, P., Ferrant, A., Verdonck, L. Niederwieser, D. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia. (1995) Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood, 86, 2041 2050.
    • (1995) Blood , vol.86 , pp. 2041-2050
    • Kolb, H.J.1    Schattenberg, A.2    Goldman, J.M.3    Hertenstein, B.4    Jacobsen, N.5    Arcese, W.6    Ljungman, P.7    Ferrant, A.8    Verdonck, L.9    Niederwieser, D.10
  • 18
    • 0035202651 scopus 로고    scopus 로고
    • Effect of slow lymphocyte recovery and type of graft-versus-host disease prophylaxis on relapse after allogeneic bone marrow transplantation for acute myelogenous leukemia
    • Kumar, S., Chen, M.G., Gastineau, D.A., Gertz, M.A., Inwards, D.J., Lacy, M.Q., Tefferi, A. Litzow, M.R. (2001) Effect of slow lymphocyte recovery and type of graft-versus-host disease prophylaxis on relapse after allogeneic bone marrow transplantation for acute myelogenous leukemia. Bone Marrow Transplantation, 28, 951 956.
    • (2001) Bone Marrow Transplantation , vol.28 , pp. 951-956
    • Kumar, S.1    Chen, M.G.2    Gastineau, D.A.3    Gertz, M.A.4    Inwards, D.J.5    Lacy, M.Q.6    Tefferi, A.7    Litzow, M.R.8
  • 19
    • 70449711157 scopus 로고    scopus 로고
    • Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts
    • Le Dieu, R., Taussig, D.C., Ramsay, A.G., Mitter, R., Miraki-Moud, F., Fatah, R., Lee, A.M., Lister, T.A. Gribben, J.G. (2009) Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts. Blood, 114, 3909 3916.
    • (2009) Blood , vol.114 , pp. 3909-3916
    • Le Dieu, R.1    Taussig, D.C.2    Ramsay, A.G.3    Mitter, R.4    Miraki-Moud, F.5    Fatah, R.6    Lee, A.M.7    Lister, T.A.8    Gribben, J.G.9
  • 20
    • 34447341170 scopus 로고    scopus 로고
    • Delayed attainment of full donor chimaerism following alemtuzumab-based reduced-intensity conditioning haematopoeitic stem cell transplantation for acute myeloid leukaemia and myelodysplastic syndromes is associated with improved outcomes
    • Lim, Z.Y., Pearce, L., Ho, A.Y., Barber, L., Ingram, W., Usai, M., Tobal, K., Devereux, S., Pagliuca, A. Mufti, G.J. (2007) Delayed attainment of full donor chimaerism following alemtuzumab-based reduced-intensity conditioning haematopoeitic stem cell transplantation for acute myeloid leukaemia and myelodysplastic syndromes is associated with improved outcomes. British Journal of Haematology, 138, 517 526.
    • (2007) British Journal of Haematology , vol.138 , pp. 517-526
    • Lim, Z.Y.1    Pearce, L.2    Ho, A.Y.3    Barber, L.4    Ingram, W.5    Usai, M.6    Tobal, K.7    Devereux, S.8    Pagliuca, A.9    Mufti, G.J.10
  • 21
    • 67650745994 scopus 로고    scopus 로고
    • Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab
    • Matthews, K., Lim, Z., Afzali, B., Pearce, L., Abdallah, A., Kordasti, S., Pagliuca, A., Lombardi, G., Madrigal, J.A., Mufti, G.J. Barber, L.D. (2009) Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab. Haematologica, 94, 956 966.
    • (2009) Haematologica , vol.94 , pp. 956-966
    • Matthews, K.1    Lim, Z.2    Afzali, B.3    Pearce, L.4    Abdallah, A.5    Kordasti, S.6    Pagliuca, A.7    Lombardi, G.8    Madrigal, J.A.9    Mufti, G.J.10    Barber, L.D.11
  • 22
    • 0035669518 scopus 로고    scopus 로고
    • Mixed chimaerism is common at the time of acute graft-versus-host disease and disease response in patients receiving non-myeloablative conditioning and allogeneic stem cell transplantation
    • Mattsson, J., Uzunel, M., Brune, M., Hentschke, P., Barkholt, L., Stierner, U., Aschan, J. Ringden, O. (2001) Mixed chimaerism is common at the time of acute graft-versus-host disease and disease response in patients receiving non-myeloablative conditioning and allogeneic stem cell transplantation. British Journal of Haematology, 115, 935 944.
    • (2001) British Journal of Haematology , vol.115 , pp. 935-944
    • Mattsson, J.1    Uzunel, M.2    Brune, M.3    Hentschke, P.4    Barkholt, L.5    Stierner, U.6    Aschan, J.7    Ringden, O.8
  • 25
    • 34548776920 scopus 로고    scopus 로고
    • Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation
    • Mohty, M., Avinens, O., Faucher, C., Viens, P., Blaise, D. Eliaou, J.F. (2007) Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation. Haematologica, 92, 1004 1006.
    • (2007) Haematologica , vol.92 , pp. 1004-1006
    • Mohty, M.1    Avinens, O.2    Faucher, C.3    Viens, P.4    Blaise, D.5    Eliaou, J.F.6
  • 26
    • 0033826799 scopus 로고    scopus 로고
    • Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia
    • Molldrem, J.J., Lee, P.P., Wang, C., Felio, K., Kantarjian, H.M., Champlin, R.E. Davis, M.M. (2000) Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nature Medicine, 6, 1018 1023.
    • (2000) Nature Medicine , vol.6 , pp. 1018-1023
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3    Felio, K.4    Kantarjian, H.M.5    Champlin, R.E.6    Davis, M.M.7
  • 28
    • 33847189975 scopus 로고    scopus 로고
    • Increased frequencies of CD4(+)CD25(high) T(regs) correlate with disease relapse after allogeneic stem cell transplantation for chronic myeloid leukemia
    • Nadal, E., Garin, M., Kaeda, J., Apperley, J., Lechler, R. Dazzi, F. (2007) Increased frequencies of CD4(+)CD25(high) T(regs) correlate with disease relapse after allogeneic stem cell transplantation for chronic myeloid leukemia. Leukemia, 21, 472 479.
    • (2007) Leukemia , vol.21 , pp. 472-479
    • Nadal, E.1    Garin, M.2    Kaeda, J.3    Apperley, J.4    Lechler, R.5    Dazzi, F.6
  • 29
    • 0842307308 scopus 로고    scopus 로고
    • Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: Toxicity, chimerism, and disease responses
    • Peggs, K.S., Thomson, K., Hart, D.P., Geary, J., Morris, E.C., Yong, K., Goldstone, A.H., Linch, D.C. Mackinnon, S. (2004) Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses. Blood, 103, 1548 1556.
    • (2004) Blood , vol.103 , pp. 1548-1556
    • Peggs, K.S.1    Thomson, K.2    Hart, D.P.3    Geary, J.4    Morris, E.C.5    Yong, K.6    Goldstone, A.H.7    Linch, D.C.8    MacKinnon, S.9
  • 30
    • 0032079672 scopus 로고    scopus 로고
    • Identification of patients who may benefit from prophylactic immunotherapy after bone marrow transplantation for acute myeloid leukemia on the basis of lymphocyte recovery early after transplantation
    • Powles, R., Singhal, S., Treleaven, J., Kulkarni, S., Horton, C. Mehta, J. (1998) Identification of patients who may benefit from prophylactic immunotherapy after bone marrow transplantation for acute myeloid leukemia on the basis of lymphocyte recovery early after transplantation. Blood, 91, 3481 3486.
    • (1998) Blood , vol.91 , pp. 3481-3486
    • Powles, R.1    Singhal, S.2    Treleaven, J.3    Kulkarni, S.4    Horton, C.5    Mehta, J.6
  • 31
    • 2542418030 scopus 로고    scopus 로고
    • Low dendritic cell count after allogeneic hematopoietic stem cell transplantation predicts relapse, death, and acute graft-versus-host disease
    • Reddy, V., Iturraspe, J.A., Tzolas, A.C., Meier-Kriesche, H.U., Schold, J. Wingard, J.R. (2004) Low dendritic cell count after allogeneic hematopoietic stem cell transplantation predicts relapse, death, and acute graft-versus-host disease. Blood, 103, 4330 4335.
    • (2004) Blood , vol.103 , pp. 4330-4335
    • Reddy, V.1    Iturraspe, J.A.2    Tzolas, A.C.3    Meier-Kriesche, H.U.4    Schold, J.5    Wingard, J.R.6
  • 32
    • 30744443483 scopus 로고    scopus 로고
    • A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses
    • Reddy, P., Maeda, Y., Liu, C., Krijanovski, O.I., Korngold, R. Ferrara, J.L. (2005) A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses. Nature Medicine, 11, 1244 1249.
    • (2005) Nature Medicine , vol.11 , pp. 1244-1249
    • Reddy, P.1    Maeda, Y.2    Liu, C.3    Krijanovski, O.I.4    Korngold, R.5    Ferrara, J.L.6
  • 33
    • 0141889279 scopus 로고    scopus 로고
    • Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation
    • Rezvani, K., Grube, M., Brenchley, J.M., Sconocchia, G., Fujiwara, H., Price, D.A., Gostick, E., Yamada, K., Melenhorst, J., Childs, R., Hensel, N., Douek, D.C. Barrett, A.J. (2003) Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. Blood, 102, 2892 2900.
    • (2003) Blood , vol.102 , pp. 2892-2900
    • Rezvani, K.1    Grube, M.2    Brenchley, J.M.3    Sconocchia, G.4    Fujiwara, H.5    Price, D.A.6    Gostick, E.7    Yamada, K.8    Melenhorst, J.9    Childs, R.10    Hensel, N.11    Douek, D.C.12    Barrett, A.J.13
  • 36
    • 0032006125 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases
    • Slavin, S., Nagler, A., Naparstek, E., Kapelushnik, Y., Aker, M., Cividalli, G., Varadi, G., Kirschbaum, M., Ackerstein, A., Samuel, S., Amar, A., Brautbar, C., Ben-Tal, O., Eldor, A. Or, R. (1998) Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood, 91, 756 763.
    • (1998) Blood , vol.91 , pp. 756-763
    • Slavin, S.1    Nagler, A.2    Naparstek, E.3    Kapelushnik, Y.4    Aker, M.5    Cividalli, G.6    Varadi, G.7    Kirschbaum, M.8    Ackerstein, A.9    Samuel, S.10    Amar, A.11    Brautbar, C.12    Ben-Tal, O.13    Eldor, A.14    Or, R.15
  • 37
    • 0030752411 scopus 로고    scopus 로고
    • Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning
    • Sykes, M., Szot, G.L., Swenson, K.A. Pearson, D.A. (1997) Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning. Nature Medicine, 3, 783 787.
    • (1997) Nature Medicine , vol.3 , pp. 783-787
    • Sykes, M.1    Szot, G.L.2    Swenson, K.A.3    Pearson, D.A.4


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