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Volumn 138, Issue 4, 2007, Pages 517-526

Delayed attainment of full donor chimaerism following alemtuzumab-based reduced-intensity conditioning haematopoeitic stem cell transplantation for acute myeloid leukaemia and myelodysplastic syndromes is associated with improved outcomes

Author keywords

Acute myeloid leukaemia; Alemtuzumab; Myelodysplastic syndromes; Reduced intensity conditioning; T cell chimaerism

Indexed keywords

ALEMTUZUMAB; BUSULFAN; CD3 ANTIGEN; CYCLOSPORIN A; FLUDARABINE;

EID: 34447341170     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2007.06676.x     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 0034769445 scopus 로고    scopus 로고
    • Establishment of complete and mixed donor chimerism after allogeneic lymphohematopoietic transplantation: Recommendations from a workshop at the 2001 Tandem Meetings of the International Bone Marrow Transplant Registry and the American Society of Blood and Marrow Transplantation
    • Antin, J.H., Childs, R., Filipovich, A.H., Giralt, S., Mackinnon, S., Spitzer, T. Weisdorf, D. (2001) Establishment of complete and mixed donor chimerism after allogeneic lymphohematopoietic transplantation: recommendations from a workshop at the 2001 Tandem Meetings of the International Bone Marrow Transplant Registry and the American Society of Blood and Marrow Transplantation. Biology of Blood and Marrow Transplantation, 7, 473 485.
    • (2001) Biology of Blood and Marrow Transplantation , vol.7 , pp. 473-485
    • Antin, J.H.1    Childs, R.2    Filipovich, A.H.3    Giralt, S.4    MacKinnon, S.5    Spitzer, T.6    Weisdorf, D.7
  • 8
    • 0023551293 scopus 로고
    • Mixed blood chimerism in T cell-depleted bone marrow transplant recipients: Evaluation using DNA polymorphisms
    • Bretagne, S., Vidaud, M., Kuentz, M., Cordonnier, C., Henni, T., Vinci, G., Goossens, M. Vernant, J.P. (1987) Mixed blood chimerism in T cell-depleted bone marrow transplant recipients: evaluation using DNA polymorphisms. Blood, 70, 1692 1695.
    • (1987) Blood , vol.70 , pp. 1692-1695
    • Bretagne, S.1    Vidaud, M.2    Kuentz, M.3    Cordonnier, C.4    Henni, T.5    Vinci, G.6    Goossens, M.7    Vernant, J.P.8
  • 10
    • 0033230960 scopus 로고    scopus 로고
    • Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: Full donor T-cell chimerism precedes alloimmune responses
    • Childs, R., Clave, E., Contentin, N., Jayasekera, D., Hensel, N., Leitman, S., Read, E.J., Carter, C., Bahceci, E., Young, N.S. Barrett, A.J. (1999) Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses. Blood, 94, 3234 3241.
    • (1999) Blood , vol.94 , pp. 3234-3241
    • Childs, R.1    Clave, E.2    Contentin, N.3    Jayasekera, D.4    Hensel, N.5    Leitman, S.6    Read, E.J.7    Carter, C.8    Bahceci, E.9    Young, N.S.10    Barrett, A.J.11
  • 11
    • 0142184380 scopus 로고    scopus 로고
    • T- and B-cell immune reconstitution and clinical outcome in patients with multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell transplantation with an alemtuzumab-containing conditioning regimen followed by escalated donor lymphocyte infusions
    • D'Sa, S., Peggs, K., Pizzey, A., Verfuerth, S., Thuraisundaram, D., Watts, M., White, H., Hale, G., Waldmann, H., Goldstone, A., Mackinnon, S. Yong, K. (2003) T- and B-cell immune reconstitution and clinical outcome in patients with multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell transplantation with an alemtuzumab-containing conditioning regimen followed by escalated donor lymphocyte infusions. British Journal of Haematology, 123, 309 322.
    • (2003) British Journal of Haematology , vol.123 , pp. 309-322
    • D'Sa, S.1    Peggs, K.2    Pizzey, A.3    Verfuerth, S.4    Thuraisundaram, D.5    Watts, M.6    White, H.7    Hale, G.8    Waldmann, H.9    Goldstone, A.10    MacKinnon, S.11    Yong, K.12
  • 12
    • 0141475940 scopus 로고    scopus 로고
    • Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation
    • Dey, B.R., McAfee, S., Colby, C., Sackstein, R., Saidman, S., Tarbell, N., Sachs, D.H., Sykes, M. Spitzer, T.R. (2003) Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation. Biology of Blood and Marrow Transplantation, 9, 320 329.
    • (2003) Biology of Blood and Marrow Transplantation , vol.9 , pp. 320-329
    • Dey, B.R.1    McAfee, S.2    Colby, C.3    Sackstein, R.4    Saidman, S.5    Tarbell, N.6    Sachs, D.H.7    Sykes, M.8    Spitzer, T.R.9
  • 13
    • 21244483043 scopus 로고    scopus 로고
    • Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol
    • Domenig, C., Sanchez-Fueyo, A., Kurtz, J., Alexopoulos, S.P., Mariat, C., Sykes, M., Strom, T.B. Zheng, X.X. (2005) Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol. Journal of Immunology, 175, 51 60.
    • (2005) Journal of Immunology , vol.175 , pp. 51-60
    • Domenig, C.1    Sanchez-Fueyo, A.2    Kurtz, J.3    Alexopoulos, S.P.4    Mariat, C.5    Sykes, M.6    Strom, T.B.7    Zheng, X.X.8
  • 14
    • 0022602179 scopus 로고
    • Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease
    • Hill, R.S., Petersen, F.B., Storb, R., Appelbaum, F.R., Doney, K., Dahlberg, S., Ramberg, R. Thomas, E.D. (1986) Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease. Blood, 67, 811 816.
    • (1986) Blood , vol.67 , pp. 811-816
    • Hill, R.S.1    Petersen, F.B.2    Storb, R.3    Appelbaum, F.R.4    Doney, K.5    Dahlberg, S.6    Ramberg, R.7    Thomas, E.D.8
  • 15
    • 4444283753 scopus 로고    scopus 로고
    • Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning
    • Ho, A.Y., Pagliuca, A., Kenyon, M., Parker, J.E., Mijovic, A., Devereux, S. Mufti, G.J. (2004) Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning. Blood, 104, 1616 1623.
    • (2004) Blood , vol.104 , pp. 1616-1623
    • Ho, A.Y.1    Pagliuca, A.2    Kenyon, M.3    Parker, J.E.4    Mijovic, A.5    Devereux, S.6    Mufti, G.J.7
  • 16
    • 10244244934 scopus 로고    scopus 로고
    • Effect of mixed chimerism on graft-versus-host disease, disease recurrence and survival after HLA-identical marrow transplantation for aplastic anemia or chronic myelogenous leukemia
    • Huss, R., Deeg, H.J., Gooley, T., Bryant, E., Leisenring, W., Clift, R., Buckner, C.D., Martin, P., Storb, R. Appelbaum, F.R. (1996) Effect of mixed chimerism on graft-versus-host disease, disease recurrence and survival after HLA-identical marrow transplantation for aplastic anemia or chronic myelogenous leukemia. Bone Marrow Transplantation, 18, 767 776.
    • (1996) Bone Marrow Transplantation , vol.18 , pp. 767-776
    • Huss, R.1    Deeg, H.J.2    Gooley, T.3    Bryant, E.4    Leisenring, W.5    Clift, R.6    Buckner, C.D.7    Martin, P.8    Storb, R.9    Appelbaum, F.R.10
  • 17
    • 6344228589 scopus 로고    scopus 로고
    • Mixed hematopoietic chimerism at day 90 following allogenic myeloablative stem cell transplantation is a predictor of relapse and survival
    • Lamba, R., Abella, E., Kukuruga, D., Klein, J., Savasan, S., Abidi, M.H., Mohamed, A. Peres, E. (2004) Mixed hematopoietic chimerism at day 90 following allogenic myeloablative stem cell transplantation is a predictor of relapse and survival. Leukemia, 18, 1681 1686.
    • (2004) Leukemia , vol.18 , pp. 1681-1686
    • Lamba, R.1    Abella, E.2    Kukuruga, D.3    Klein, J.4    Savasan, S.5    Abidi, M.H.6    Mohamed, A.7    Peres, E.8
  • 19
    • 0027092058 scopus 로고
    • Myeloid and lymphoid chimerism after T-cell-depleted bone marrow transplantation: Evaluation of conditioning regimens using the polymerase chain reaction to amplify human minisatellite regions of genomic DNA
    • Mackinnon, S., Barnett, L., Bourhis, J.H., Black, P., Heller, G. O'Reilly, R.J. (1992) Myeloid and lymphoid chimerism after T-cell-depleted bone marrow transplantation: evaluation of conditioning regimens using the polymerase chain reaction to amplify human minisatellite regions of genomic DNA. Blood, 80, 3235 3241.
    • (1992) Blood , vol.80 , pp. 3235-3241
    • MacKinnon, S.1    Barnett, L.2    Bourhis, J.H.3    Black, P.4    Heller, G.5    O'Reilly, R.J.6
  • 20
    • 0036720416 scopus 로고    scopus 로고
    • Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: A critical role for host antigen-presenting cells
    • Mapara, M.Y., Kim, Y.M., Wang, S.P., Bronson, R., Sachs, D.H. Sykes, M. (2002) Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells. Blood, 100, 1903 1909.
    • (2002) Blood , vol.100 , pp. 1903-1909
    • Mapara, M.Y.1    Kim, Y.M.2    Wang, S.P.3    Bronson, R.4    Sachs, D.H.5    Sykes, M.6
  • 24
    • 0842307308 scopus 로고    scopus 로고
    • Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: Toxicity, chimerism, and disease responses
    • Peggs, K.S., Thomson, K., Hart, D.P., Geary, J., Morris, E.C., Yong, K., Goldstone, A.H., Linch, D.C. Mackinnon, S. (2004) Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses. Blood, 103, 1548 1556.
    • (2004) Blood , vol.103 , pp. 1548-1556
    • Peggs, K.S.1    Thomson, K.2    Hart, D.P.3    Geary, J.4    Morris, E.C.5    Yong, K.6    Goldstone, A.H.7    Linch, D.C.8    MacKinnon, S.9
  • 28
    • 0032006125 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases
    • Slavin, S., Nagler, A., Naparstek, E., Kapelushnik, Y., Aker, M., Cividalli, G., Varadi, G., Kirschbaum, M., Ackerstein, A., Samuel, S., Amar, A., Brautbar, C., Ben-Tal, O., Eldor, A. Or, R. (1998) Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood, 91, 756 763.
    • (1998) Blood , vol.91 , pp. 756-763
    • Slavin, S.1    Nagler, A.2    Naparstek, E.3    Kapelushnik, Y.4    Aker, M.5    Cividalli, G.6    Varadi, G.7    Kirschbaum, M.8    Ackerstein, A.9    Samuel, S.10    Amar, A.11    Brautbar, C.12    Ben-Tal, O.13    Eldor, A.14    Or, R.15
  • 30
    • 14344264156 scopus 로고    scopus 로고
    • Mixed hematopoietic chimerism for the simultaneous induction of T and B cell tolerance
    • Sykes, M., Shimizu, I. Kawahara, T. (2005) Mixed hematopoietic chimerism for the simultaneous induction of T and B cell tolerance. Transplantation, 79, S28 S29.
    • (2005) Transplantation , vol.79
    • Sykes, M.1    Shimizu, I.2    Kawahara, T.3


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