New insights on the protein-ligand interaction differences between the two primary cellular retinol carriers

Journal of Lipid Research

Volumn 51, Issue 6, 2010, Pages 1332-1343

  Franzoni, Lorella ^a   Cavazzini, Davide ^a   Rossi, Gian Luigi ^a   Lücke, Christian ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

Author keywords

barrel fold; Cellular retinol binding proteins; Hydrogen deuterium exchange; Intracellular lipid binding proteins; Ligand affinity; Nuclear magnetic resonance; Spectroscopy structural stability

Indexed keywords

ALANINE; ARGININE; CELLULAR RETINOL BINDING PROTEIN; CELLULAR RETINOL BINDING PROTEIN 1; CELLULAR RETINOL BINDING PROTEIN 2; DEUTERIUM; HYDROGEN; ISOLEUCINE; LYSINE; PHENYLALANINE; RETINOL; THREONINE; UNCLASSIFIED DRUG; VALINE;

ALPHA HELIX; AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOSOL; GENETIC CONSERVATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; RAT; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; APOPROTEINS; DEUTERIUM EXCHANGE MEASUREMENT; EVOLUTION, MOLECULAR; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; RATS; RETINOL-BINDING PROTEINS, CELLULAR; SEQUENCE ALIGNMENT; VITAMIN A;

EID: 77952688100     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M002006     Document Type: Article

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